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21.
Abstract: Background: Identification of risk drinking in expectant fathers may be helpful as an important part of efforts to minimize maternal alcohol use, and as an opportunity to inform them about a problematic practice during a critical developmental stage for the couple. The purpose of this study was to evaluate the T‐ACE screening questionnaire, which asks about t olerance to alcohol, being a nnoyed by other's comments about drinking, attempts to c ut down, and having a drink first thing in the morning (“ e ye‐opener”), in the male partners of pregnant women who themselves were T‐ACE positive. Methods: Two hundred fifty‐four male partners were asked to complete the T‐ACE embedded in a health survey, the Alcohol Use Disorders Identification Test (AUDIT), and other questions about their alcohol use in the past 30 days when their pregnant partners had a median gestation of 11.5 weeks (T1). After delivery, male partners again completed the T‐ACE and quantity‐frequency questions (T2). The predictive ability of the T‐ACE and AUDIT was compared, using risk drinking (>4 drinks/day or >14 drinks/week) as the criterion standard. Results: A substantial minority of male partners had risk drinking, 31 percent at T1 and 25 percent at T2. Although the AUDIT was better than the T‐ACE as an independent predictor of risk drinking, the latter was most accurate when the tolerance threshold exceeded 2 drinks, the same established for pregnant women. The sensitivity (T1 = 84.6%, T2 = 82.8%) and specificity (T1 = 43.8%, T2 = 51.1%) of the T‐ACE at this threshold compared favorably with those of the AUDIT at the standard cut point of 8. Conclusions: The T‐ACE may be a practical way for clinicians to identify risk drinking in both pregnant women and expectant fathers. (BIRTH 33:2 June 2006) 相似文献
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23.
外阴汗腺癌七例临床分析 总被引:2,自引:0,他引:2
目的:总结外阴汗腺癌的临床特点及治疗方法。方法:对7例外阴汗腺癌病例进行回顾性分析。结果:外阴汗腺癌的发病年龄为40~58岁。7例患者的治疗为局部扩大切除或根治性外阴广泛切除,2例辅以术后放疗。7例中5例存活5年以上,其中1例曾在首次治疗后第7年、11年2次复发并于第17年死于肿瘤。2例存活<5年,1例在术后2年半死于脑出血,1例因脊椎广泛转移在术后1年零9个月死亡。结论:外阴汗腺癌的预后较好,局部扩大切除或根治性外阴切除,是首选治疗方法。 相似文献
24.
Reversal of diabetes in BB rats by transplantation of encapsulated pancreatic islets 总被引:8,自引:0,他引:8
Prolonged survival of pancreatic islet allografts implanted in diabetic BB rats was achieved by encapsulation of individual islets in a protective biocompatible alginate-polylysine-alginate membrane without immunosuppression. Intraperitoneal transplantation of the encapsulated islets reversed the diabetic state of the recipients within 3 days and maintained normoglycemia for 190 days. Normal body weight and urine volume were maintained during this period, and no cataracts were detected in the transplant recipients. In contrast, control rats receiving transplants of unencapsulated islets experienced normoglycemia for less than 2 wk. These results demonstrated that microencapsulation can protect allografted islets from both graft rejection and autoimmune destruction without immunosuppression in an animal model that mimics human insulin-dependent diabetes. 相似文献
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目的:探讨EB病毒感染与人大肠癌发生的关系。方法:用原位分子杂交法对130例人大肠癌标本中EB病毒小分子RNA片段进行检测。结果:130例标本中有6例(4.48%)癌组织呈阳性反应,其中4例为男性,4例有明显淋巴细胞浸润。结论:EB病毒感染可能与我国部分大肠腺癌的发生有关,肿瘤细胞间质中大量淋巴细胞浸润可能是EB病毒感染的重要病理学特征。 相似文献
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Rifampin alone or with trimethoprim for contacts of children with Haemophilus influenzae type b infections. 总被引:1,自引:0,他引:1 下载免费PDF全文
T Jadavji R Cheung R M Bannatyne C G Prober 《Canadian Medical Association journal》1986,135(4):328-331
We carried out a nonrandomized, unblinded study to compare the efficacy of rifampin alone with that of rifampin in combination with trimethoprim in the eradication of the Haemophilus influenzae type b (HIB) carrier state among contacts of patients with invasive HIB infection. The study population comprised 17 index patients admitted to hospital with severe HIB infections and 233 contacts, 43 of whom had nasopharyngeal colonization with HIB of the same biotype as that of the index patient. Rifampin in a daily dose of 20 mg/kg (maximum 600 mg) for 4 days eradicated the carrier state in 86% of cases, as did the combination of rifampin at the same dosage and trimethoprim in a daily dose of 5 mg/kg (maximum 160 mg) for 4 days. 相似文献
29.
Kenneth K. H. Chao BS Eric Cheung BS William B. Armstrong MD Brian J. F. Wong MD 《Otolaryngology--head and neck surgery》2002,126(6):593
Objective: The study goal was to compare the laser spot size created using reflective and refractive micromanipulators with a CO2 laser and to determine the sensitivity of spot size to laser power. Study Design and Setting: A CO2 laser and operating microscope (400-mm focal length) was coupled to either a reflective (Cassegrain-like) or refractive micromanipulator. Laser spot size was determined by measuring the region of ablation created by laser irradiation of wood (dry tongue depressors), exposed photographic film, and agar gel using optical micrometry. Laser power varied from 0.5 to 20 W with pulse durations of 0.1 and 0.5 second. Results: The reflective micromanipulator demonstrated overall smaller spot sizes for a given laser power and lower incremental change in spot size with increasing power. The reflective design demonstrated less sensitivity to increases in laser power. Conclusions: Micromanipulator optical design can result in significant differences in laser spot size. The reflective device used in this study demonstrated less sensitivity to increasing laser power. (Otolaryngol Head Neck Surg 2002;126:593-597.) 相似文献
30.
报告12例疸性腔皮病患者的性别与年龄构成、并发症、实验室检查、治疗经过和结果,对该病的病因、治疗和预后进行了讨论。 相似文献