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排序方式: 共有3825条查询结果,搜索用时 15 毫秒
81.
82.
Kishimoto M Takaya T Ohshima T Sakamoto D Ikezawa N Shioya Y Oshima T Kumekawa Y Sasajima K Koshima Y Sakimura K Adachi A Kaneko K 《Nihon Shokakibyo Gakkai zasshi》2012,109(6):961-968
A 31-year-old man was admitted to our hospital because of upper abdominal pain. He had been diagnosed with ulcerative colitis (UC) at age 28, but the disease has been in remission since then. On admission, he had slight fever, abdominal pain, and bloody stools six times a day, and the serum levels of pancreatic enzyme and IgG4 were elevated. Diffuse enlargement of the pancreas was detected by abdominal computed tomography; furthermore, narrowing of the main pancreatic duct was revealed using endoscopic retrograde cholangiopancreatography. Based on these findings, he was given a diagnosis of autoimmune pancreatitis (AIP) associated with UC. Both diseases improved without using steroids. After discharge, he has not had any recurrence of AIP or UC despite not being on steroid treatment, although the serum IgG4 level has shown a slight tendency to elevate. 相似文献
83.
Yohei Hamaue Jiro Nakano Yuki Sekino Sayaka Chuganji Jyunya Sakamoto Toshiro Yoshimura Tomoki Origuchi Minoru Okita 《The journal of physiological sciences : JPS》2013,63(6):401-408
This study examined mechanical and thermal hypersensitivity in the rat hind paw during cast immobilization of the hind limbs for 4 or 8 weeks and following cast removal. Blood flow, skin temperature, and volume of the rat hind paw were assessed in order to determine peripheral circulation of the hind limbs. Sensitization was analyzed by measuring the expression of the calcitonin gene-related peptide (CGRP) in the spinal dorsal horn following cast immobilization. Two weeks post immobilization, mechanical and thermal sensitivities increased significantly in all rats; however, peripheral circulation was not affected by immobilization. Cast immobilization for 8 weeks induced more serious hypersensitivity compared to cast immobilization for 4 weeks. Moreover, CGRP expression in the deeper lamina layer of the spinal dorsal horn increased in the rats immobilized for 8 weeks but not in those immobilized for 4 weeks. These findings suggest that immobilization-induced hypersensitivity develops during the immobilization period without affecting peripheral circulation. Our results also highlight the possibility that prolonged immobilization induces central sensitization in the spinal cord. 相似文献
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86.
Momohara S Inoue E Ikari K Yano K Tokita A Honjo Y Sakuma Y Hiroshima R Iwamoto T Seto Y Tanaka E Taniguchi A Yamanaka H 《Modern rheumatology / the Japan Rheumatism Association》2012,22(2):209-215
The treatment of rheumatoid arthritis (RA) has improved dramatically with the advent of the latest generation of disease-modifying antirheumatic drugs. Despite these advances, in some patients inflammation is not diminished sufficiently to prevent irreversible musculoskeletal damage, thereby necessitating surgical intervention to reduce pain and improve function. For RA treatment, Japanese orthopedic surgeons also prescribe medication. In this study, we examined whether this Japanese system is effective for RA treatment. We analyzed the clinical condition of RA patients treated by rheumatologists and those treated by orthopedists in a linked registry study using information from a large observational cohort of RA patients followed every half year from 2000 to 2010 (the IORRA cohort). Two groups of patients were compared: patients treated by rheumatologists (rheumatologic group) and patients treated by orthopedists (orthopedic group). The results revealed that patients in the orthopedic group were older, more likely to be female, and had a longer disease duration than patients in the rheumatologic group. The proportion of patients with a history of joint surgery was also much higher in the orthopedic group than in the rheumatologic group. The average scores on the Japanese version of the Health Assessment Questionnaire, and the remission ratio determined using a Boolean-based definition gradually increased from 2000 until 2010, and these findings were consistently better in the rheumatologic group than in the orthopedic group. These data suggest that patients treated primarily by orthopedists are more likely to have long-standing RA compared to patients treated by rheumatologists. Therefore, it is critical for rheumatologists and orthopedists to complement each other medically in the treatment of RA patients. 相似文献
87.
Takahashi T Asano Y Amiya E Hatano M Tamaki Z Ozeki A Watanabe A Kawarasaki S Nakao T Taniguchi T Ichimura Y Toyama T Watanabe M Hirata Y Nagai R Sato S 《Modern rheumatology / the Japan Rheumatism Association》2012,22(4):598-601
Intravenous cyclophosphamide pulse therapy (IVCY) exerts its efficacy against interstitial lung disease (ILD) associated with systemic sclerosis (SSc) by restoring vascular injuries as well as aberrant immune activation. We recently experienced two patients with SSc-ILD in whom the values of brachial flow-mediated dilation (FMD) reflected the efficacy of IVCY. We herein report the details of these cases and discuss the potential of FMD to predict and evaluate the effect of IVCY on SSc-ILD. 相似文献
88.
Chikaraishi Yohei Arakaki Yoshikuni Koizumi Hideki 《International ophthalmology》2021,41(7):2485-2494
International Ophthalmology - To evaluate the temporary changes in visual outcomes and anterior segment parameters after cataract surgery plus low-add bifocal intraocular lens (IOL) implantation... 相似文献
89.
Rin Asao Katsuhiko Asanuma Fumiko Kodama Miyuki Akiba-Takagi Yoshiko Nagai-Hosoe Takuto Seki Yukihiko Takeda Isao Ohsawa Satoshi Mano Kiyoshi Matsuoka Hiroyuki Kurosawa Shinya Ogasawara Yoshiaki Hirayama Sakari Sekine Satoshi Horikoshi Masanori Hara Yasuhiko Tomino 《Clinical journal of the American Society of Nephrology》2012,7(9):1385-1393
90.
Jun Takahashi Hirokazu Kobayashi Shinji Wakabayashi Masao Deguchi Hidehiro Ito Yuji Mogami Hirotaka Tanikawa Hiroyuki Nakagawa Hideki Moriya Ryohei Ashizawa Kenji Takahara Hisatoshi Kinoshita Yutaka Tateiwa Hiromichi Misawa Takahiro Tsutsumimoto Taku Nakakohji Yohei Yuzawa Akihito Sawaumi Yohei Hidai Satoshi Matsuda Isao Nakamura Shigeyuki Toba Mikio Kamimura Takeshi Nakane Hiroki Hirabayashi Hiroyuki Hashidate Nobuhide Ogihara Keijiro Mukaiyama Hiroyuki Kato Kuniyoshi Ohtsuka 《Journal of orthopaedic science》2013,18(2):208-215