首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   35037篇
  免费   3345篇
  国内免费   2415篇
耳鼻咽喉   281篇
儿科学   524篇
妇产科学   387篇
基础医学   3738篇
口腔科学   727篇
临床医学   4560篇
内科学   5311篇
皮肤病学   329篇
神经病学   1363篇
特种医学   1310篇
外国民族医学   15篇
外科学   3672篇
综合类   6089篇
现状与发展   7篇
一般理论   2篇
预防医学   2501篇
眼科学   1012篇
药学   3964篇
  26篇
中国医学   2117篇
肿瘤学   2862篇
  2024年   162篇
  2023年   608篇
  2022年   1521篇
  2021年   1917篇
  2020年   1488篇
  2019年   1203篇
  2018年   1257篇
  2017年   1222篇
  2016年   1106篇
  2015年   1691篇
  2014年   2108篇
  2013年   1967篇
  2012年   2751篇
  2011年   2887篇
  2010年   1999篇
  2009年   1616篇
  2008年   1958篇
  2007年   1847篇
  2006年   1764篇
  2005年   1413篇
  2004年   1112篇
  2003年   946篇
  2002年   828篇
  2001年   671篇
  2000年   656篇
  1999年   650篇
  1998年   450篇
  1997年   429篇
  1996年   379篇
  1995年   355篇
  1994年   323篇
  1993年   197篇
  1992年   215篇
  1991年   166篇
  1990年   130篇
  1989年   139篇
  1988年   133篇
  1987年   139篇
  1986年   111篇
  1985年   98篇
  1984年   41篇
  1983年   36篇
  1982年   18篇
  1981年   24篇
  1980年   18篇
  1979年   15篇
  1978年   5篇
  1977年   12篇
  1976年   8篇
  1961年   1篇
排序方式: 共有10000条查询结果,搜索用时 12 毫秒
31.
Syndiotactic polystyrene was efficiently prepared in the presence of a homogeneous catalyst composed of (η5-cyclopentadienyl)tribenzyloxytitanium and methylaluminoxane (MAO) as a cocatalyst. Influences of various polymerization conditions, e.g., [Ti]. [MAO], [St], temperature and the content of retained trimethylaluminium (TMA) in MAO on the catalytic activity, syndiotacticity and molecular weight of the polymer were studied. It was found that the retained TMA plays an important role in the polymerization. Lowering the retained TMA content in MAO decreases the activity of the catalyst remarkably. Addition of external alkylaluminium (TMA or triisobutylaluminium) into the catalyst system with MAO containing low amounts of retained TMA promotes styrene polymerization.  相似文献   
32.
肢端黏液样炎性纤维母细胞肉瘤2例及文献复习   总被引:1,自引:2,他引:1  
目的探讨肢端黏液样炎性纤维母细胞肉瘤的临床病理学特征及鉴别诊断。方法对2例发生在下肢末端的黏液样炎性纤维母细胞肉瘤进行光镜观察和免疫组化标记,并复习文献。结果2例发生在下肢末端的病程较长的渐进性肿块,术后局部复发。镜检:病变呈多结节状,边界不清;黏液样基质中见数量不等的各类炎细胞浸润,散在或灶性分布梭形、奇异形和多空泡状脂肪母细胞样3种形态的瘤细胞。免疫表型:肿瘤细胞Vim弥漫阳性,CD68和CD34灶性阳性,CK、SMA、HHF-35、S-100蛋白、CD45、CD45R0、CD15、CD30均阴性。结论此病病程较长,术后易局部复发,是一种低度恶性的肿瘤。鉴于病变黏液样基质及各类炎细胞浸润的背景较为突出,而特征性的瘤细胞稀疏,应注意与炎症性病变或具有相似组织形态的良性或恶性肿瘤鉴别。  相似文献   
33.
1993年9月以来,用自血光量子治疗各型病毒性肝炎72例,结果所有患者症状均明显好转或消失,SB异常者恢复正常和有效分别占66.7%和90.2%,ALT异常者恢复正常和有效分别为77.4%和100%,血清白蛋白平均上升4.2g/L,球蛋白下降4.6g/L,三项凝血功能(PT、HPT、KPTT)测定结果表明量子血疗不会引起或加重肝炎患者的凝血障碍。61例乙型肝炎患者HBeAg和HBsAg的阴转率分别达59.3%和15%。  相似文献   
34.
Unlike the penetrating monoenergetic 662 keV gamma rays emitted by 137Cs LDR sources, the spectrum of 192Ir used in HDR brachytherapy contains low-energy components. Since these are selectively absorbed by the high-atomic number materials of which intracavitary applicators are made, the traditional neglect of applicator attenuation can lead to appreciable dose errors. We investigated the attenuation effects of a uterine applicator, and of a set of commonly used vaginal cylinders. The uterine applicator consists of a stainless steel source guide tube with a wall thickness of 0.5 mm and a density of 8.02 g/cm3, whereas the vaginal cylinders consist of the same stainless steel tube plus concentric polysulfone cylinders with a radius of 1 or 2 cm and a density of 1.40 g/cm3. Monte Carlo simulations were performed to compute dose distributions for a bare 192Ir-HDR source, and for the same source located within the applicators. Relative measurements of applicator attenuation using ion-chambers (0.125 cm3) confirmed the Monte Carlo results within 0.5%. We found that the neglect of the applicator attenuation overestimates the dose along the transverse plane by up to 3.5%. At oblique angles, the longer photon path within applicators worsens the error. We defined attenuation-corrected radial dose and anisotropy functions, and applied them to a treatment having multiple dwell positions inside a vaginal cylinder.  相似文献   
35.
应用模糊极小极大神经网络研究了化合物复杂结构和性能(QSAR)之间的关系,用该法进行几组化合物致癌的识别,结果优于线性回归的方法,对此作出一些分析。  相似文献   
36.
37.
Ye Z  Parry JM 《Mutagenesis》2002,17(5):361-364
The human expressed sequence tag (EST) database provides a wealth of resources, which can be used to rapidly screen for potential polymorphisms in proteins of physiological interest. The human p53R2 gene, a recently identified ribonucleotide reductase, plays an important role in DNA repair and is involved in the pathway of p53 activity in response to the presence of DNA damage. On the basis of the alignment of human EST sequences, we identified three candidate polymorphisms at nt 2752, 2759 and 4696 in the 3'-untranslated region of the p53R2 gene. The presence of these polymorphisms was confirmed in a Caucasian population (n = 82) by allele-specific PCR and PCR/restriction fragment length polymorphism analyses. The rare allele frequency at position 4696 (15.5%) is higher than either rare allele frequency at position 2752 or 2759 (6 and 6%). Our results suggest that the human EST data may serve as a valuable source for the rapid identification of genetic variation.  相似文献   
38.
Summary Two polymorphic dinucleotide (CA) repeat dones were isolated from a CEPH mega-YAC clone (844E2), and were localized to chromosome 8 using a panel of 13 mouse/human somatic cell hybrids.  相似文献   
39.
40.
The endothelial cell (EC) -specific secreted protein EGFL7 is important for tubulogenesis in newly forming blood vessels. We studied its role in vascular tube formation by a quantitative ultrastructural analysis of Egfl7-knockdown zebrafish embryos. At 24 hours postfertilization, the endothelia of dorsal aorta (DA) and posterior cardinal vein (PCV) were correctly anchored to the hypochord and endoderm, respectively, but failed to expand into the vascular area. This resulted in vessels with reduced or split lumen and open sheets of ECs. Concomitantly, the organization of hematopoietic cells-identified by the presence of previously undescribed membrane tubules-between DA and PCV, and within the vessels, was severely disturbed. Strikingly, ectopic cell junctions occurred across the obstructed vessel lumen, on the luminal EC surfaces, which in control conditions never display junctions of any kind. These data suggest that Egfl7 provides ECs with a cue for their extension into the vascular area and in establishing EC cell polarity.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号