沸石分子筛材料中次级孔的研究——Ⅱ.Y型沸石晶内次级孔对扩散的影响

以含有次级孔的沸石的晶内扩散为研究对象,对来源于同一NaY母体的一组改性Y型沸石,进行了孔结构分析和正戊烷的扩散系数的测定。得到了具不同次级孔量的Y型沸石晶内扩散性能变化的规律。并采用随机游动方法对实际的Y型沸石晶内扩散进行模拟,得到了与实验测定一致的结果,从而可以对有次级孔的Y型沸石的晶内扩散做定量的估计。     

催化分光光度法测定人发中微量铁

拟定了一简单实用的测定人发中铁的催化分光光度法。在实验条件下,人发中常见的数10种微量元素均不干扰铁的测定,回收率达86～106%。     

碳—钛组合式人工股骨头临床应用15年随访

自1980年4月至1995年4月,应用碳—钛组合式人工股骨头治疗髋关节疾患319例。随访最短1年,最长15年。随访结果:股骨颈骨折组优良率93％,股骨头无菌性坏死组优良率89.8％。余者2例失败,4例髋关节周围钙化,2例碳质头略大,3例假体下沉,1例类风湿性髋关节强直,术后关节再强直。1例髋臼硬化,4例6髋关节明显疼痛。4例死于心血管疾病。我们体会到碳质材料具有良好的物理、化学性能和生物相容性,是一种优良的人工关节材料。碳—钛组合式人工股骨头是目前优良的人工假体之一。     

Effect of Central Muscarine Receptor Blockade with DKJ-21 on the Blood Pressure and Heart Rate in Stress-Induced Hypertensive Rats

Da-Nian Zhu, Long-Mei Xue, Peng Li. Effect of central muscarine receptor blockade. with DKJ-21 on the blood pressure and heart rote in stress-induced hypertensive rats.

The experiments were performed on Wistar or Sprague-Dawley rats of both sexes divided at random into stress and control groups. The rats in the stress groups were put into cages and subjected to electric foot-shocks and noises for 9-15 days, which caused an increase in blood pressure (BP) and heart rate (HR). In hypertensive rats DKJ-21 (4mg/lml) was injected intravenously (i.v.), and 0.5-1.0h after administration the BP and HR dropped from the high level to normotensive level. In normotensive rats, however, administration of DKJ-21 had no effect on BP or HR. In separate groups of normotensive rats, pretreatment of DKJ-21 (4 mg/l ml, i.v.) blocked the pressor and tachycardiac effect induced by microinjection of physostigmine (0.4μg/0.1 /μl/site), corticosterone (40μg/0.1μl/site) or aldosterone (40 μg/0.1 μl/site) into the rostral ventrolateral medulla (rVLM). Furthermore, DKJ-21 also attenuated the enhancement of the pressor response to stimulation of the defense area in the midbrain, which was induced by microinjection of drugs (mentioned above) into the rVLM. These results indicate that i.v. DKJ-21 can selectively block the muscarinic receptors in the rVLM in stress-induced hypertensive rats, which suggests that abnormal enhancement of cholinergic mechanism in the rVLM may be related to hypertensive effects of corticoids in this area.     

玻璃纤维表面的乙烯基单体接枝聚合

用玻璃纤维表面处理剂ＭＡＣ处理玻璃纤维后，再进行臭氧处理，使玻璃纤维的表面产生活性中心，引发苯乙烯、甲基丙烯酸甲酯、及丙烯酸等乙烯基单体在玻璃纤维表面上接枝聚合。接枝纤维的密度减小，对水的浸润性下降，红外光谱及扫描电镜观察证明玻璃纤维表面上接枝聚合物的存在。     

白细胞介素—2胸腔灌注治疗恶性胸水24例临床分析

恶性胸腔积液能严重影响病人的呼吸循环功能,加速病人死亡。本文对24例恶性胸腔积液病人给予白细胞介素—2(IL-2)胸腔灌注治疗,取得了明显效果。其总有效率(完全缓解率 部分缓解率)较对照组有显著性差异(P<0.05),该作者认为该疗法治疗效果肯定,副作用轻,具有推广应用价值。     

pH指示剂吸收度比值法测定盐酸乙胺丁醇的含量

本文报道pH指示剂吸收度比值法测定盐酸乙胺丁醇的含量。该法采用指示剂为0.05%茜素黄R,测定波长374nm和500nm;标准液为0.1mol/L NaOH;仪器为WFZ-800D_2型分光光度计。测得三批盐酸乙胺丁醇的含量分别为99.5±0.04%,99.4±0.05%和99.6±0.03%.同时与药典法比较,结果一致。     

胚胎脊髓细胞悬液植入急性成年大鼠损伤脊髓

目的：建立胚胎脊髓细胞悬液移植于脊髓损伤模型，以评价其治疗脊髓损伤的可能性。方法：４２只Ｗｉｓｔａｒ大鼠以改良Ａｌｅｎ法（５０ｇｃｍ）打击脊髓，３天后将孕１４天（Ｅ１４）ＦＳＣＳ２０μｌ植入损伤空腔，移植后２、４、６、８、１０、１２周，以光、电镜、免疫组织化学观察移植物存活、分化及其与宿主之间关系。结果：移植细胞逐渐长大。充满不规则空腔，宿主ＮＦ、５－ＨＴ、ＣＧＲＰ纤维分别出现于移植物，ＧＦＡＰ纤维于宿主移植物交界处适量存在。移植成神经细胞、成少突胶质细胞、成星形细胞的细胞器日渐完善，细胞功能活跃。复杂及多样突触与细胞连接，将上述细胞与神经纤维、胶质纤维、毛细血管网在三维空间内连接成一体，并与宿主紧密嵌合。结论：（１）成年大鼠脊髓损伤３天后植入ＦＳＣＳ可以存活。（２）移植物进入宿主后，出现再分布，继而器官样分化。（３）长、短传导束进入移植物，显示了移植物的桥作用。（４）成少突胶质细胞的神经营救作用。（５）移植区内出现多种突触，提示移植物中继作用的可能性。     

Effect of temperature in focal ischemia of rat brain studied by 31P and 1H spectroscopic imaging

³¹P, ¹H and lactate spectroscopic imaging was used to evaluate the effects of hypothermia on focal cerebral ischemia produced by middle cerebral artery occlusion. The effects on high energy phosphate metabolism, pH, lactate and NAA were investigated in 24 spontaneously hypertensive rats subjected to either permanent or transient ischemia. Under either normothermic (37.5°C) or hypothermic (32°C) conditions, with permanent 6-h occlusion, there was little difference between groups in either the NMR measurements or the volume of infarction. In animals that underwent 3 h of ischemia followed by 12 h of reperfusion, the ischemic changes in lactate, pH, NAA, and high-energy phosphate returned toward control values, and there was a protective effect of hypothermia (infarct volume of 211 ± 26 and 40 ± 14 mm³ in normothermic and hypothermic groups, respectively). Thus, hypothermia did not ameliorate the changes in lactate, pH, NAA, or high energy phosphate levels occurring during ischemia, however, during reperfusion there was an improvement in both the recovery of these metabolites and pathological outcome in hypothermic compared with normothermic animals.     

不同膳食特点地区中老年人血红蛋白及其与膳食营养的关系

测定分析不同膳食特点地区975例年龄45～74岁中老年人的血红蛋白及其与膳食营养素的关系。结果牧民及城市居民贫血率低，北京及新疆托里分别为7.6％和4.6％。男性比女性血红蛋白高，血红蛋白随年龄增加而降低。相关分析结果血红蛋白与膳食热能、蛋白质、动物蛋白质与总蛋白质比值呈显著正相关。结果说明血红蛋白可用于中老年人营养状态监测。