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71.
颅脑转移瘤的CT和MRI研究 总被引:1,自引:0,他引:1
134例颅脑转移瘤,CT增强薄层扫描88例,其中延迟扫描58例;薄层MRI 44例。114例(85%)有幕上转移,38例(28%)有幕下转移。73例(54%)多发,64例(46%)单发。增强MRI显示清晰和尚清晰者为42例(95%),增强后1~3min CT延迟扫描显示清晰和尚清晰者为55例(95%),延迟3min以上显示清晰和尚清晰为95%。可见,增强CT延迟扫描和大剂量增强CT对颅脑转移瘤的检出效果与增强MRI是相仿的。 相似文献
72.
目的探讨肿胀技术在体表外科手术中的应用价值。方法随机选择体表肿物与先天性畸形、体表瘢痕、乳房整形、脂肪抽吸、腹壁整形、除皱、隆胸、褥疮、面瘫及颅骨电烧伤等230例体表外科手术应用肿胀技术,成人164例,完全采用肿胀法局麻技术,儿童66例,在全麻下应用肿胀技术。并与相应手术非肿胀法下施行进行了比较。结果脂肪抽吸术中利多卡因用量可达30~60mg/kg体重。肿胀技术具有易于进行解剖间隙的分离、减少术中失血、增强麻醉效果、增加手术安全性和术后恢复快等优点。结论肿胀技术可推广到体表外科手术中广泛应用,对儿童更为适宜,对减少输血造成的疾病具有重要意义。 相似文献
73.
目的:评价世行贷款结核病项目实施效果,掌握疫情现状,为制度2001-2010年防治规划提供理论依据。方法:按照《第四次全国结核病流行病学抽样调查工作手册》对2个随机抽样点人群进行流调。结果:活动性肺结核13例,患病率和涂阳患病率434.8/10万,33.4/10万,较1990年流设疫情分别下降了43.4%和27.3%,BCG接种率34.9%,较1996年流调提高了一倍。结论:以控制传染源为目的:以DOTS为核心的结核病控制策略是成功的,可行的,政府的行政干预及保持必要的经费投入,对结核病控制可持续发展具有重要意义。农村儿童及新生儿BCG接种工作亟待改善。 相似文献
74.
海藻、甘草及其相伍用对小鼠肝药酶的影响 总被引:5,自引:0,他引:5
目的:研究海藻、甘草单煎液及其不同比例合煎,单煎后混合液以及单体A、B;C、D、E对小鼠肝药酶的影响。方法:取小鼠随机分组,分别ig给药,qd,连续4d后禁食20h,处死取肝脏,称重后制成匀浆,紫外分光光度计于450nm,490nm波长下测其光密度值,计算肝匀浆中细胞色素P-450的含量。结果:甘草、甘草与海藻合煎液及单体A,B,C,D,E均能显著提高小鼠肝匀浆中细胞色素P-450的含量,而海藻,甘草与海藻单煎后混合液未能提高小鼠肝心浆中的细胞色素P-450的含量。结论:甘草,甘草与海藻合煎液及单体,A,B,C,D,E均能显著提高小鼠肝匀浆中细胞色素P-450的含量,对肝药酶有诱导作用。 相似文献
75.
足组织缺损的显微修复 总被引:15,自引:11,他引:4
1984年~1994年共收治各种足部组织创伤缺损236例,均采用显微外科技术进行组织移植修复,其中单纯皮瓣移植修复187例,复合皮瓣移植修复49例。吻合血管游离移植修复97例,带血管蒂移位修复139例。4例前足缺损者用带肩胛骨的复合皮瓣移植修复,6例足跟严重缺损者用带血管的腓骨复合皮瓣移植修复。经1~10年随访,皮瓣、复合皮瓣、移植或再植的骨骨各全部成活,愈合良好,足功能基本得到恢复,可行走、负重,186例恢复了原工作。认为,恢复足部结构完整与重建足跟、足底的感觉是获得良好功能的关键 相似文献
76.
乙基叔丁醚对动物局部和全身的毒性研究 总被引:3,自引:0,他引:3
为了主人乙基叔丁醚(ETBE)的毒性作用,探讨它的灌注溶解治疗胆固醇结石的可能性。我们做了该药物的动物毒性实验,对比ETBE和MTBE(甲基叔丁醚)对动物的局部组织和全身毒性作用。局部毒性实验是对大白兔胆囊进行灌注后,病理观察组织变化。全身毒性实验是通过对小鼠腹腔注射药物的半致死量作对比。结果发现,ETBE对兔的胆囊、胆部属这和十二指肠的损害较MTBE组动物轻。ETBE摇篮腔注射半致死量LD50) 相似文献
77.
Gerbils are much more sensitive to the hepatotoxic and lethal effects of CCl4 than rats as indicated by 48-hr LD50 values (0.08 vs 2.8 ml/kg). On the other hand, gerbils are refractory to chlordecone (CD) potentiation of CCl4 toxicity. To investigate the possible mechanism underlying the high sensitivity of gerbils to CCl4 lethality, the metabolism of CCl4 was studied in gerbils pretreated with dietary CD, phenobarbital (PB), or mirex (M) at 10, 225, and 10 ppm, respectively. The hepatic content of 14CCl4, the expiration of 14CCl4 and 14CCl4-derived 14CO2, and lipid peroxidation were measured and the results were compared with the previous data for rats. After the 15-day dietary pretreatment, male gerbils (60-80 g) received 14CCl4 (0.08 ml/kg; sp act 0.04 mCi/mmol) ip in corn oil and the radioactivity present in the expired air was collected for 6 hr. More than 80% of the parent compound as represented by the 14C-label in the toluene trap was expired in 6 hr regardless of the pretreatments. Expiration of 14CO2 measured during the 6 hr after 14CCl4 administration in control gerbils was 3.5-fold more than that in rats and was significantly increased in pretreated groups (M greater than PB greater than CD). PB and M pretreatments resulted in a significant increase of 14C-label bound to the nonlipid fraction of the liver as compared with CD-treated or control gerbils. The radiolabel present in the livers of control gerbils was 5-fold higher than that of rats. In vivo lipid peroxidation measured as diene conjugation in lipid extracts from the livers was lower in gerbils than in rats, and none of the pretreatments significantly affected lipid peroxidation. The serum alanine aminotransferase and aspartate aminotransferase were significantly elevated at 6 hr after CCl4 injection in all groups of gerbils. These data indicate that the more extensive metabolism of CCl4, as represented by 14CO2 formation and 14C-label bound to hepatic tissue, in gerbils as compared with rats, may partially explain the high sensitivity of gerbils to CCl4 toxicity. However, the enhanced metabolism of CCl4 found in CD-, PB-, or M-pretreated gerbils did not lead to amplified hepatotoxic and lethal effects of CCl4. The reason gerbils may be refractory to CD amplification of CCl4 injury might be associated with other factors yet to be investigated. 相似文献
78.
J. Pepke-Zaba T. W. Higenbottam A. T. Dinh Xuan J. P. Scott T. A. H. English J. Wallwork 《Transplant international》1990,3(1):108-112
Abstract. Twenty-one patients were studied at rest and during exercise after heart transplantation to compare cardiac output measured by thermodilution and impedance cardiography. Exercise was performed on a bicycle ergometer over a limited range of work load (25 and 50 watt) whilst metabolic gas exchange was recorded. One patient was studied at rest whilst his circulation was maintained by a Jarvik-7 artificial heart. The values of cardiac output measured by impedance cardiography corresponded closely with the flow rate from the artificial heart. There was also close agreement between the impedance and thermodilution measurements of cardiac output at rest and during exercise. Both measurements followed the changes in heart rate and oxygen consumption. Both thermodilution and impedance cardiography methods elicited good reproducibility of cardiac output measurements at rest and during exercise. These observations suggest that the noninvasive and continuous record of cardiac output obtained by impedance cardiography can be used for the postoperative monitoring of heart transplant recipients. 相似文献
79.
本研究采用先进的三维超声成像技术及多普勒技术对正常育龄妇女月经周期中心血管功能进行研究。结果:月经周期中HR、BP无变化;血清E2是周期性变化,排卵前达高峰。SV、CO、EF在排卵前期升高达峰值,显著高于月经期和黄体期;SVR排卵前期最低,而Ved、Ves无变化。Vmax、A、E在内源性E2高峰时明显加快,而E/A比值无明显变化。结果提示:月经周期中随内源性E2的周期性变化,心脏功能也发生周期性变化。E2高峰时,心输出量、心搏量和射血分数达最高。外周阻力最低,心脏内血流速度加快。 相似文献
80.