类固醇激素在变应性鼻炎治疗中的应用

目的：对类固醇激素在变应性鼻炎治疗中的应用作一综述,方法：对类固醇激素在变应性鼻炎治疗中的应用加以分析,整理。结果：展现类固醇激素在变应性鼻炎治疗领域的最新成果,结论：选择合适的应用方法,有地临床医师运用类固醇激素在主为应性鼻炎的治疗中提高疗效,避免或尽量减少副作用的发生。     

NMDA受体与NOS在大鼠脊髓中间外侧柱的定位和生后发育

目的 探讨N-甲基-天冬氨酸受体（NMDAR1和NMDAR2A/B亚基）、一氧化氮合酶（NOS）及还原型辅酶Ⅱ硫辛酰胺脱氢酶（NADPH-d）活性在大鼠脊髓中间外侧柱（IML）的定位与生后发育特征。方法 在甲醛固定的脊髓切片上,进行ABC法免疫染色和NADPH-d组织化学反应与半定量分析。结果 MMDAR1,NMDAR2A/B,NOS I和NADPH-d反应产物丰富地分布于IML,主要定位于神经元胞体、树突和轴突样纤维终末。在生后早期发育中它们具有明显的动态变化,生后7d(P7）有微弱或中等的表达,随后逐渐上调,P21或P28达到高峰,然后保持于此水平于成体动物。结论 NMDA受体-NO通路可能是脊髓交感节前神经元一条重要的细胞内信号途径,并参与神经元生后发育成熟的调控过程。     

瞬间反应式二次谐波显像评价正常犬肝脏超声学造影的实验研究

目的：评价瞬间反应二次谐波显像（Ｔｒａｎｓｉｅｎｔ ｒｅｓｐｏｎｓｅ ｓｅｃｏｎｄ ｈａｒｍｏｎｅｃ ｉｍａｇｉｎｇ,ＴＲＳＨＩ）对正常肝脏声学造影的增强效果及动态变化规律,并与常规连续二次谐波显像进行对比分析。方法：６只健康杂种犬 经外周静脉注射氟碳声学造影剂,分别用常规二次谐波显像和瞬间反应式二次谐波显像扫描肝脏。造影效果评价使用视觉评分和视频密度分析。结果：常规二次谐波显像有４次Ｉ级增强、４     

The characteristics of the use and the levels of diffusion of nonconventional medicine

The national trends of the utilisation of non conventional therapies suggest that an increasing number of patients employ remedies that are outside the mainstream of what has been defined as conventional western medicine. The extent to which these practices have clinical efficacy according to biomedical criteria is a matter of ongoing debate. It may be that independent of any such efficacy, the attraction of alternative medicine is related to the power of its underline shared beliefs and cultural assumptions. The fundamental premises are an advocacy of nature, vitalism, "science" and spirituality. For patients, who choose alternative medicine, the most important reason to abandon conventional therapies could be to move from the sterile "high-tech" realm of official medicine to a more intimate "high-touch" intervention offered by non-physicians.     

高压下滴流床反应器动持液量的测定

在常压－２．０ＭＰａ的系统压力下测定了滴流床中气－液两相并流下流动的动持液量,了气－液流率,液相粘度,填料大小,压力以及床层高度对动持液量的影响。实验结果表明增中液体流率动持流量增加,气体流率增加时,结果相反粘度的增加对动持液量的影响不大,动持液量随填料空隙率的增大而变小。     

聚丙烯酰胺凝胶电泳分析615纯系小鼠血清蛋白

目的：根据各种蛋白质在一定的泳动条件下,都有一定的相对迁移率不同的特点,分析６１５ 纯系小鼠血清中的蛋白质在聚丙烯酰胺凝胶上的分布,进行了定位分析。方法：采用高ｐＨ 不连续性聚丙烯酰胺凝胶电泳及蛋白质特殊染色法。结果：６１５ 鼠血清蛋白质在聚丙烯酰胺凝胶上可分离出１３ ～１５ 条区带,脂蛋白３ 条、白蛋白２ 条、糖蛋白５ 条、铜蓝蛋白１ 条、血红蛋白１ 条、结合珠蛋白３ 条。根据每种蛋白质的Ｒｍ 值定位顺序从阳极到阴极依次为１ ．糖蛋白、２．脂蛋白、３ ．白蛋白、４．脂蛋白、５ ．糖蛋白、６ ．巨球蛋白（ 根据其它资料） 、７ ．铜蓝蛋白、８ ．结合珠蛋白、９ ．Ｈｂ、１０ ．运铁蛋白（ 根据其它资料）、１１ ．脂蛋白、１２ ～１４ ．均为糖蛋白。光密度扫描６１５ 鼠血清蛋白质相对面积比分别为白蛋白为４８－４、α１ 球蛋白为６－９、α２ 球蛋白２３－８ 、β球蛋白为５－０ 、γ球蛋白为１３－８ 。结论：６１５ 鼠血清蛋白质的定位分析对于６１５ 鼠可移植性淋巴细胞型白血病鼠的蛋白质研究具有一定的实际意义,利用Ｒｍ 值来作蛋白质定位分析简单易行,关键在于掌握实验条件的恒定。     

Endothelin antagonist treatment for successful liver transplantation from non-heart-beating donors

BACKGROUND: With the shortage of cadaveric donors, non-heart-beating donors (NHBDs) are a potential source of liver allografts. However, warm ischemic injury in NHBDs seriously affects the viability of graft liver. Endothelin (ET)-1 has been reported to be involved in the hepatic microcirculatory disturbances after ischemia-reperfusion. METHODS: In a porcine orthotopic liver transplantation model, changes in the serum and liver tissue ET-1 concentration were measured and the effects of an ET receptor antagonist, TAK-044, were evaluated. After cardiac arrest of the donors, liver allografts were subjected to 90 min of warm ischemia, flushed, and preserved for 4 hr at 4 degrees C. The pigs were divided into two groups: a control group (no drug treatment) and a drug-treated group, in which donors and recipients were treated with TAK-044 (10 mg/kg body, drip intravenous injection). Both groups had six donor/recipient pairs. RESULTS: -The ET-1 concentration in the hepatic venous blood increased after reperfusion of the graft in the control group recipients. ET-1 in the graft liver significantly increased during the cold preservation period. TAK-044 treatment significantly increased recipient 7-day survival rate. After reperfusion of the graft, the concentrations of serum liver enzymes and arterial lactate in the drug-treated group were significantly lower than in the control group. The postoperative increase in portal venous pressure was significantly reduced in the drug-treated group. Measurements of liver enzymes in the washed-out preservation fluid at the time of graft rinsing indicated that TAK-044 treatment of the donors significantly suppressed liver enzyme release during ischemia. CONCLUSIONS: These findings indicate TAK-044 treatment has protective effects on postoperative function of hepatic allografts procured from NHBDs.     

基于Windows的S12数字程控交换机人机命令查询系统的设计与实现

介绍了基于Windows3.x环境下,用Delphi开发软件,结合面象对象技术、数据库技术、Windows帮助文件系统技术,开发S12数字程控交换机人机命令信息查询系统的过程和方法.并对超文本技术、面向对象技术、数据库技术进行了阐述.通过试运行,验证了本系统的高速、方便、安全、兼容性好等特点.     

视力客观检测方法的研究

目的研究用视觉诱发电位（ｖｉｓｕａｌｅｖｏｋｅｄｐｏｔｅｎｔｉａｌ,ＶＥＰ）作为视力客观检测的可行性。方法对４０只视力不等的患眼和５０只正常眼,分别记录用不同大小方格（８°、４°、２°、１°、３０、１５和６）刺激时的ＶＥＰ波形。结果患眼组和正常组Ｐ１００振幅及潜时在统计学上有显著性差异。视力与能诱发出波形的最小方格间有明显关系：最小方格为６、１５、３０和１°,平均视力分别为１．１３,０．６２,０．１８和０．０７。视力与Ｐ１００振幅呈正相关,与潜时呈负相关。结论用诱发出ＶＥＰ波形的最小方格大小可估计患者的视力范围