全文获取类型
收费全文 | 106695篇 |
免费 | 9078篇 |
国内免费 | 6192篇 |
专业分类
耳鼻咽喉 | 1133篇 |
儿科学 | 1570篇 |
妇产科学 | 2327篇 |
基础医学 | 12635篇 |
口腔科学 | 1993篇 |
临床医学 | 14260篇 |
内科学 | 16814篇 |
皮肤病学 | 905篇 |
神经病学 | 5740篇 |
特种医学 | 3606篇 |
外国民族医学 | 47篇 |
外科学 | 11456篇 |
综合类 | 15265篇 |
现状与发展 | 23篇 |
一般理论 | 21篇 |
预防医学 | 6261篇 |
眼科学 | 2884篇 |
药学 | 10967篇 |
64篇 | |
中国医学 | 5016篇 |
肿瘤学 | 8978篇 |
出版年
2024年 | 306篇 |
2023年 | 1563篇 |
2022年 | 4003篇 |
2021年 | 5126篇 |
2020年 | 3671篇 |
2019年 | 3327篇 |
2018年 | 3642篇 |
2017年 | 3024篇 |
2016年 | 2944篇 |
2015年 | 4550篇 |
2014年 | 5787篇 |
2013年 | 5125篇 |
2012年 | 7676篇 |
2011年 | 8414篇 |
2010年 | 5074篇 |
2009年 | 3893篇 |
2008年 | 5344篇 |
2007年 | 5599篇 |
2006年 | 5463篇 |
2005年 | 5746篇 |
2004年 | 3865篇 |
2003年 | 3425篇 |
2002年 | 3044篇 |
2001年 | 2466篇 |
2000年 | 2686篇 |
1999年 | 2740篇 |
1998年 | 1604篇 |
1997年 | 1508篇 |
1996年 | 1322篇 |
1995年 | 1173篇 |
1994年 | 992篇 |
1993年 | 644篇 |
1992年 | 1006篇 |
1991年 | 813篇 |
1990年 | 687篇 |
1989年 | 602篇 |
1988年 | 594篇 |
1987年 | 533篇 |
1986年 | 422篇 |
1985年 | 330篇 |
1984年 | 208篇 |
1983年 | 159篇 |
1982年 | 85篇 |
1981年 | 98篇 |
1980年 | 83篇 |
1979年 | 115篇 |
1978年 | 54篇 |
1977年 | 56篇 |
1975年 | 44篇 |
1974年 | 45篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
A Well-Balanced Positivity-Preserving Quasi-Lagrange Moving Mesh DG Method for the Shallow Water Equations
下载免费PDF全文
![点击此处可从《Communications In Computational Physics》网站下载免费的PDF全文](/ch/ext_images/free.gif)
A high-order, well-balanced, positivity-preserving quasi-Lagrange moving
mesh DG method is presented for the shallow water equations with non-flat bottom
topography. The well-balance property is crucial to the ability of a scheme to simulate perturbation waves over the lake-at-rest steady state such as waves on a lake or
tsunami waves in the deep ocean. The method combines a quasi-Lagrange moving
mesh DG method, a hydrostatic reconstruction technique, and a change of unknown
variables. The strategies in the use of slope limiting, positivity-preservation limiting,
and change of variables to ensure the well-balance and positivity-preserving properties are discussed. Compared to rezoning-type methods, the current method treats
mesh movement continuously in time and has the advantages that it does not need to
interpolate flow variables from the old mesh to the new one and places no constraint
for the choice of a update scheme for the bottom topography on the new mesh. A selection of one- and two-dimensional examples are presented to demonstrate the well-balance property, positivity preservation, and high-order accuracy of the method and
its ability to adapt the mesh according to features in the flow and bottom topography. 相似文献
22.
Yuanqing Yao Jun Qian Shunkang Rong Yuwen Huang Bo Xiong Gang Yang Dengqing Zhang Shimin Deng Jie Tan Que Zhu Changming Deng Dichuan Liu Haitao Ran Zhigang Wang Jing Huang 《Ultrasound in medicine & biology》2019,45(2):490-499
Stellate ganglion (SG) modification has been investigated for arrhythmia treatment. In this study, transesophageal SG imaging and intervention were explored using a homemade 30F integrated focused ultrasonic catheter in healthy mongrel canines in vivo. Anatomic details of SGs were ultrasonically imaged and evaluated. SG had a heterogeneous echoic structure and characteristic profiles sketched by hyper-echoic outlines in an ultrasonogram. Left SGs in the experimental group were successfully ablated through the esophagus under ultrasonic guidance provided by the catheter itself. Two weeks after the ablation, the QT and QTc of the experimental group decreased compared with those of the sham group and at baseline (both p values < 0.001). Histologic examination revealed that left SGs were destroyed. No major complications were observed. This approach may be further explored as a method for ganglia remodeling evaluation and as a strategy of ganglia modification for arrhythmia and for other diseases. 相似文献
23.
Peng Cheng Linlin Yang Xiaodan Huang Xuejun Wang Maoqing Gong 《Archiv der Pharmazie》2020,353(4):1900350
Malaria, one of the most striking, re-emerging infectious diseases caused by the genus Plasmodium, places a huge burden on global healthcare systems. A major challenge in the control and eradication of malaria is the continuous emergence of increasingly widespread drug-resistant malaria, creating an urgent need to develop novel antimalarial agents. Chalcone derivatives are ubiquitous in nature and have become indispensable units in medicinal chemistry applications due to their diverse biological profiles. Many chalcone derivatives demonstrate potential in vitro and in vivo antimalarial activity, so chalcone could be a useful template for the development of novel antimalarial agents. This review covers the recent development of chalcone hybrids as antimalarial agents. The critical aspects of the design and structure–activity relationship of these compounds are also discussed. 相似文献
24.
25.
Tian-Yuan Xiong Fang-Yang Huang Qi Liu Yong Peng Yuan-Ning Xu Jia-Fu Wei 《Annals of medicine》2020,52(7):361-366
Abstract
Background
Comorbidities are commonly seen in patients with coronavirus disease 2019 (COVID-19), but the clinical implication is not yet well-delineated. We aim to characterize the prevalence and clinical implications of comorbidities in patients with COVID-19. 相似文献26.
27.
Chen Rong Zhang Yuan Huang Lei Cheng Bi-heng Xia Zhong-yuan Meng Qing-tao 《Journal canadien d'anesthésie》2020,67(6):655-663
Canadian Journal of Anesthesia/Journal canadien d'anesthésie - To assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus... 相似文献
28.
29.
30.
Fuying Chen Linting Huang Changcan Li Jia Zhang Weiqin Yang Beibei Zhang Huaguo Li Dan Deng Jianying Liang Jinwen Shen Zhirong Yao Ming Li 《Clinical genetics》2020,98(2):179-184
Epidermolysis bullosa (EB) is a heritable blistering disorder. We performed a next-generation sequencing-based multigene panel test and successfully predicted 100% of the EB types, including, 36 EB simplex (EBS), 13 junctional EB (JEB), 86 dystrophic EB (DEB), and 3 Kindler EB. Chinese JEB and recessive DEB (RDEB) patients have relatively mild phenotypes; for severe type separately accounts for 45.5% and 23.8%, respectively. We identified 96 novel and 49 recurrent pathogenic variants in 11 genes, although we failed to detect the second mutation in one JEB and five RDEB patients. We identified one novel p.E475K mosaic mutation in the clinically normal mother of one out of 13 EBS patients with KRT5 mutations, one recurrent p.G2034R mosaic mutation, and one novel p.G2043R mosaic mutation in the clinically normal relatives of two out of 19 dominant DEB patients. This study shows that next-generation technology could be an effective tool in diagnosing EB. 相似文献