Human respiratory syncytial virus genomic and antigenic variants isolated in two hospitals during one epidemic, in Santiago, Chile.

BACKGROUND: Human respiratory syncytial virus (HRSV) is a major cause of severe lower respiratory tract infection (LRI) in children. Distinct variants of the viruses have been described. OBJECTIVE: The objective was to compare the antigenic and genetic variability of HRSV strains recovered from infants admitted to two hospitals during one epidemic in a big city. STUDY DESIGN: We analyzed nasopharyngeal aspirates from 201 infants admitted for LRI to two hospitals during 2002 in Santiago, Chile. The analyses were carried out using a panel of monoclonal antibodies against G glycoprotein epitopes (EIA) and RFLP for N and G genes. RESULTS: No differences in HRSV groups A/B and in N patterns distribution were observed among both hospitals. On the contrary, antigenic and genetic G patterns displayed a wide diversity of strains circulating during one epidemic, in one big city. CONCLUSIONS: RSV variability assessment depended rather on the tool used for analysis than on the geographical location.     

Navigating between cultures: the role of culture in youth violence.

The purpose of this paper is to review three cultural concepts (acculturation, ethnic identity, bicultural self-efficacy) and their relationship to the known risk and protective factors associated with youth violence. We conducted a review of the relevant literature that addresses these three cultural concepts and the relationship among culture, violent behavior, and associated cognition. The available literature suggests that ethnic identity and bicultural self-efficacy can be best thought of as protective factors, whereas acculturation can be a potential risk factor for youth violence. We examine the connection between these cultural concepts and the risk and protective factors described in the 2001 Surgeon General's Report on Youth Violence, and present a summary table with cultural risk and protective factors for violence prevention. These concepts can assist physicians in identifying risk and protective factors for youth violence when working with multicultural adolescents and their families. Physicians are more effective at providing appropriate referrals if they are aware that navigating among different cultures influences adolescent behavior.     

The impact of providing help: Emergency workers and cardiopulmonary resuscitation attempts

Although anecdotes suggest that emergency medical technicians often themselves have to cope with severe trauma as a result of their work, almost all empirical work has been concerned with the aftermath of disaster. Fourteen volunteer ambulance attendants were asked about resuscitation attempts in which they had been involved. It was found that many of these evidenced a persistent psychological aftermath. Some of these individuals experienced vivid, involuntary, and uncontrollable thoughts, feelings, and/or mental images concerning their attempt. Perceived control and coping responses were examined, and found to be related to the impact of the resuscitation attempt upon the ambulance personnel. Data from this preliminary investigation indicate the need for further work in the area, and with related populations, such as nonprofessionals who attempt cardiopulmonary resuscitation.