全文获取类型
收费全文 | 1217篇 |
免费 | 37篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 11篇 |
妇产科学 | 53篇 |
基础医学 | 75篇 |
口腔科学 | 21篇 |
临床医学 | 93篇 |
内科学 | 356篇 |
皮肤病学 | 6篇 |
神经病学 | 93篇 |
特种医学 | 46篇 |
外科学 | 233篇 |
综合类 | 7篇 |
预防医学 | 40篇 |
眼科学 | 59篇 |
药学 | 90篇 |
肿瘤学 | 64篇 |
出版年
2023年 | 4篇 |
2022年 | 14篇 |
2021年 | 33篇 |
2020年 | 27篇 |
2019年 | 41篇 |
2018年 | 41篇 |
2017年 | 33篇 |
2016年 | 33篇 |
2015年 | 25篇 |
2014年 | 38篇 |
2013年 | 67篇 |
2012年 | 85篇 |
2011年 | 91篇 |
2010年 | 56篇 |
2009年 | 69篇 |
2008年 | 111篇 |
2007年 | 109篇 |
2006年 | 94篇 |
2005年 | 77篇 |
2004年 | 59篇 |
2003年 | 42篇 |
2002年 | 60篇 |
2001年 | 6篇 |
2000年 | 7篇 |
1999年 | 3篇 |
1998年 | 4篇 |
1997年 | 7篇 |
1996年 | 5篇 |
1995年 | 6篇 |
1994年 | 1篇 |
1992年 | 1篇 |
1991年 | 3篇 |
1990年 | 1篇 |
1983年 | 3篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1979年 | 3篇 |
1969年 | 1篇 |
排序方式: 共有1262条查询结果,搜索用时 62 毫秒
11.
Athanasios Roumeliotis Vasilios Vaios Fotios Girtovitis Apostolos Karligkiotis Konstantinos Leivaditis Pantelis Zebekakis Vassilios Liakopoulos 《Seminars in dialysis》2020,33(4):338-342
The majority of vascular access thrombosis episodes in hemodialysis patients are due to anatomic abnormalities. Thrombophilias are inherited, acquired or mixed disorders which also predispose to venous thromboembolism. They include protein C, protein S and antithrombin deficiencies, as well as gene mutations for prothrombin and factor V Leiden. The most important of the mixed cases is hyperhomocysteinemia, which includes both a genetic and an acquired substrate. We report two patients undergoing hemodialysis who suffered from multiple thrombotic events, the first due to factor V Leiden heterozygosity and the second because of hyperhomocysteinemia due to homozygosity for MTHFR C677T mutation. As no site for vascular access was left, transfer to peritoneal dialysis for both patients improved solute clearance and quality of life with no additional thrombotic events noted. 相似文献
12.
George M. Pamboris Marika Noorkoiv Vasilios Baltzopoulos Amir A. Mohagheghi 《Scandinavian journal of medicine & science in sports》2019,29(2):200-212
The acute effects of two dynamic stretching (DS) protocols on changes in the ankle range of motion (RoM), neuromechanical, and sensorimotor properties of the plantarflexor muscle group were examined. Eighteen participants received slow (SDS) or fast dynamic stretching (FDS) on two separate days. Outcome measures were assessed pre‐ and 2 minutes post‐interventions, and included maximum dorsiflexion angle, maximum isometric torque at neutral ankle position, maximum concentric and eccentric torques, force matching capacity, joint position sense and medial gastrocnemius muscle and tendon strain. Possibly and likely small increases in dorsiflexion RoM were observed after SDS (mean ± 90% confidence intervals; 1.8 ± 1.2°) and FDS (2.1 ± 1.2°), respectively. Very likely moderate decreases in muscle strain after SDS (?38.0 ± 20.6%) and possibly small decrease after FDS (?13.6 ± 21.2%) were observed. SDS resulted in a likely beneficial small increase in tendon strain (25.3 ± 29.7%) and a likely beneficial moderate increase after FDS (41.4 ± 44.9%). Effects on strength were inconsistent. Possibly small effect on positional error after SDS (?27.1 ± 37.5%), but no clear effect after FDS was observed. Both DS protocols increased RoM, and this was more due to an increase in tendon elongation rather than the muscle. However, SDS showed greater improvement than FDS in both neuromechanical and sensorimotor performance, and hence, SDS can be recommended as part of warm‐up in sporting contexts. 相似文献
13.
Ignatiadis Ioannis A. Mavrogenis Andreas F. Igoumenou Vasilios G. Polyzois Vasilios D. Tsiampa Vasiliki A. Arapoglou Dimitrios K. Spyridonos Sarantis 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2019,29(2):295-305
European Journal of Orthopaedic Surgery & Traumatology - Gunshot wounds and blast injuries constitute a major public health problem, as the increasing availability of firearms and explosives in... 相似文献
14.
15.
Andriana C. Kaliora Aggeliki M. Kountouri Vaios T. Karathanos Lemonica Koumbi Nikolaos G. Papadopoulos Nikolaos K. Andrikopoulos 《Nutrition and cancer》2013,65(6):792-799
Currants and Sultanas (Vitis vinifera L.) are dried vine products produced in Greece and used broadly in the Mediterranean diet. We aimed to investigate the gastric cancer preventive activity of methanol extracts obtained from currants from three different origins in Greece (Vostizza, Nemea, and Messinia) as well as methanol extracts obtained from Sultanas cultivated in the island of Crete as to inhibition of cell proliferation, induction of apoptosis, and inhibition of inflammation. All extracts from 500 μg dried raisins studied suppressed cell proliferation, significantly those obtained from Sultanas from Crete and currants from Nemea. Flow cytometric analysis of Annexin-V labeled cells indicated that Cretan Sultana, Nemea, and Messinia currants at 500 μg dried product/ml medium significantly induced cell death. All extracts from 500 μg dried raisins statistically decreased protein and mRNA levels of ICAM-1 in TNF-alpha stimulated cells. Measurement of IL-8 protein levels and quantification for IL-8 mRNA showed no significant decrease. These results indicate that the methanol extracts from currants, rich in phenolic compounds, exhibit cancer preventive efficacy by limiting cell proliferation, inducing cell death, and suppressing ICAM-1 levels in AGS cells. 相似文献
16.
17.
Athyros VG Papageorgiou AA Symeonidis AN Didangelos TP Pehlivanidis AN Bouloukos VI Mikhailidis DP;GREACE Study Collaborative Group 《Angiology》2003,54(6):679-690
This is a prospective evaluation of the effect of structured care of dyslipidemia with atorvastatin (strict implementation of guidelines) versus usual care (physician's standard of care) on morbidity and mortality of patients with coronary heart disease (CHD) and diabetes mellitus (DM). From 1600 consecutive CHD patients randomized to either form of care in the GREek Atorvastatin and CHD Evaluation Study (GREACE), 313 had DM: 161 in the structured care arm and 152 in the usual care arm. All patients were followed up for a mean of 3 years. In the structured care group, patients were treated with atorvastatin to achieve the National Cholesterol Education Program (NCEP) low-density lipoprotein cholesterol (LDL-C) treatment goal of <2.6 mmol/L (100 mg/dL). Primary endpoints were all-cause and coronary mortality, coronary morbidity, and stroke. In the structured care group, 156 patients (97%) were taking atorvastatin (10-80 mg/day; mean, 23.7 mg/day) throughout the study; the NCEP LDL-C treatment goal was reached by 150 patients (93%). Only 17% (n=26) of the usual care patients were on long-term hypolipidemic drug treatment and 4% (n=6) reached the NCEP LDL-C treatment goal. During the study, 46 of 152 (30.3%) CHD patients with DM on usual care experienced a major vascular event or died versus 20 of 161 (12.5%) patients on structured care; relative risk reduction (RRR) 58%, p<0.0001. RRR for all-cause mortality was 52%, p=0.049; coronary mortality 62%, p=0.042; coronary morbidity 59%, p<0.002; and stroke 68%, p=0.046. Event rate curves started deviating from the sixth treatment month and the RRR was almost 60% by the 12th month. RRRs remained at that level until the end of the study, when they became statistically significant. The cost/life-year gained with structured care was estimated at 6200 US dollars. In CHD patients with DM, structured care of dyslipidemia with atorvastatin to achieve the NCEP LDL-C treatment goal, reduces all-cause and coronary mortality, coronary morbidity, and stroke by more than one half within a 3-year period, in comparison to usual care. Clinical benefit is manifested as early as the sixth month of treatment. 相似文献
18.
19.
20.
Doundoulakis Ioannis Gavriilaki Maria Tsiachris Dimitris Arsenos Petros Antoniou Christos-Konstantinos Dimou Smaro Soulaidopoulos Stergios Farmakis Ioannis Akrivos Evangelos Stoiloudis Panagiotis Notas Konstantinos Kimiskidis Vasilios K. Giannakoulas George Paraskevaidis Stylianos Gatzoulis Konstantinos A. Tsioufis Konstantinos 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》2022,36(5):951-958
Cardiovascular Drugs and Therapy - Atrial high-rate episodes (AHREs) recorded with cardiac implantable electronic devices (CIEDs) have been associated with the development of clinical atrial... 相似文献