全文获取类型
收费全文 | 94篇 |
免费 | 3篇 |
专业分类
儿科学 | 1篇 |
基础医学 | 5篇 |
临床医学 | 28篇 |
内科学 | 21篇 |
皮肤病学 | 11篇 |
外科学 | 16篇 |
综合类 | 1篇 |
预防医学 | 3篇 |
药学 | 11篇 |
出版年
2022年 | 1篇 |
2021年 | 1篇 |
2016年 | 4篇 |
2015年 | 2篇 |
2014年 | 6篇 |
2013年 | 3篇 |
2012年 | 4篇 |
2010年 | 1篇 |
2009年 | 4篇 |
2008年 | 2篇 |
2007年 | 7篇 |
2006年 | 4篇 |
2005年 | 3篇 |
2004年 | 1篇 |
1998年 | 6篇 |
1997年 | 5篇 |
1996年 | 6篇 |
1995年 | 3篇 |
1994年 | 3篇 |
1993年 | 1篇 |
1992年 | 5篇 |
1990年 | 6篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1976年 | 1篇 |
1957年 | 1篇 |
1955年 | 1篇 |
排序方式: 共有97条查询结果,搜索用时 10 毫秒
21.
22.
ISOTOPIC RESPONSE 总被引:3,自引:0,他引:3
RONNI WOLF M.D. SARAH BRENNER M.D. VINCENZO RUOCCO M.D. FABRIZIO GRIMALDI FILIOLI M.D. 《International journal of dermatology》1995,34(5):341-348
Background. The occurrence of a new skin disorder exactly at the site of another one, already healed and unrelated, was first described in 1955. In 1985, Wolf et al. recognized that we are dealing with a dermatologic phenomenon and established a precise definition for this phenomenon. Fifty-eight cases corresponding to the definition of this phenomenon have been reported until now. Methods. The new phenomenon, for which the term “isotopic response” has been suggested, has been defined. Cases corresponding to the definition have been analyzed with special emphasis on the diseases involved, the time intervals, and the locations of the diseases. Eight new cases are described. Results. A total of 58 cases of isotopic response have been described. The first disease in most of the patients was herpes zoster; in three cases it was herpes simplex, in two varicella, and in one, thrombophlebitis. The second disease, which appeared exactly at the site of the first, already healed disease, was in most reported cases a carcinoma (26 cases, in particular 15 cases of breast carcinoma, 5 basal cell carcinomas (BCC), 4 squamous cell carcinomas (sec), 2 basosquamous carcinomas), or granuloma annulare (16 cases). Additional diseases were Kaposi's sarcoma (2 cases), pseudolymphoma (2 cases), sarcoid (2 cases), tinea (2 cases), tuberculoid and vasculitis granuloma (1 case), angiosarcoma, metastasis, Bowen's disease, lymphoma, leukemia cutis, and acne (1 case each). The diseases did not show any predilection for a particular location. The interval between the first and second disease was extremely variable (ranging from days to years) and showed no particular features. In the eight additional cases described in the present report, the first disease was herpes simplex (6 cases) or herpes zoster (2 cases). The second disease was viral warts (3 cases) or squamous cell carcinoma (2 cases). Additional diseases were furunculosis, contact dermatitis, and molluscum contagiosum (1 case each). Conclusions. The new term, “isotopic response,” describes the occurrence of a new skin disorder at the site of another, unrelated, and already healed skin disease. It is suggested that the term “isotopic response” be included in the lexicon (glossary) of dermatology. Introducing the new term and classifying all the cases under a single key word, will make it possible to locate and collect them easily and to search for the mechanism underlying this phenomenon. 相似文献
23.
CLAUDIO COSTANTINO NICOLE BONACCORSO MARTINA SCIORTINO LUCIANO DAZZO ALESSANDRO CARUBIA DANIELA CHIFARI DANIELA SEGRETO DONATELLA MARCHESE FABRIZIO RUSSO MARIO MINORE ALESSIA PIERI GIORGIO GRAZIANO CARMELO MASSIMO MAIDA VINCENZO RESTIVO FABIO TRAMUTO FRANCESCO VITALE WALTER MAZZUCCO 《Journal of preventive medicine and hygiene》2022,63(3):E399
24.
VINCENZO GEMIGNANI M.Sc. ELISABETTA BIANCHINI M.Sc. FRANCESCO FAITA M.Sc. VINCENZO LIONETTI M.D. Ph.D. MANUELA CAMPAN M.D. FABIO ANASTASIO RECCHIA M.D. Ph.D. EUGENIO PICANO M.D. Ph.D. TONINO BOMBARDINI M.D. Ph.D. 《Pacing and clinical electrophysiology : PACE》2010,33(7):795-803
Background: Invasively measured left ventricular (LV) dP/dt is the accepted standard for measuring acute and chronic directional changes in LV contractility. Recently, we developed a noninvasive force sensor based on an accelerometer positioned on the chest, which measures the vibrations generated by isovolumic myocardial contraction. The aim of this paper was to compare noninvasive (accelerometer) versus invasive (LV dP/dt) indices of myocardial contractility in a chronic minipig model of pacing‐induced heart failure (HF). Comparative assessment was performed both at rest and following dobutamine infusion. Methods: In adult male minipigs (n = 6), LV contractility was simultaneously assessed both invasively (LV dP/dt, Millar catheter) and noninvasively (accelerometer) at rest and following dobutamine (up to 7.5 mcg/kg/min), both before and after development of HF by pacing the LV at 180 beats/min for 3 weeks. Results: Invasive and noninvasive assessments were obtained in 24 conditions (12 at rest and 12 after dobutamine infusion). Sensor‐based cardiac force changes were significantly related to positive peak LV dP/dtmax changes following dobutamine infusion both in normal (r = 0.88, P < 0.001) and failing heart (r = 0.89, P < 0.001). The force‐frequency relation showed a tight correlation between invasive and noninvasive assessment (r = 0.68, P = 0.02). Conclusions: The force‐frequency relation can be assessed noninvasively by a transthoracic sensor based on an accelerometer. The method can efficiently detect the development of resting dysfunction and the contractile reserve at different HF steps, with potential for wearable HF monitoring. (PACE 2010; 795–803) 相似文献
25.
Multipoint Left Ventricular Pacing in a Single Coronary Sinus Branch Improves Mid‐Term Echocardiographic and Clinical Response to Cardiac Resynchronization Therapy
下载免费PDF全文
![点击此处可从《Journal of cardiovascular electrophysiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
CARLO PAPPONE M.D. Ph.D. ŽARKO ĆALOVIĆ M.D. GABRIELE VICEDOMINI M.D. AMARILD CUKO M.D. LUKE C. MCSPADDEN Ph.D. KYUNGMOO RYU Ph.D. ENRICO ROMANO B.Eng. MARIO BALDI M.D. MASSIMO SAVIANO M.D. ALESSIA PAPPONE M.D. CRISTIANO CIACCIO M.D. LUIGI GIANNELLI M.D. BOGDAN IONESCU M.D. ANDREA PETRETTA M.D. RAFFAELE VITALE M.D. ANGELICA FUNDALIOTIS M.D. LUIGI TAVAZZI M.D. VINCENZO SANTINELLI M.D. 《Journal of cardiovascular electrophysiology》2015,26(1):58-63
26.
27.
VINCENZO SERRETTA GIOVANNI LO GRECO CARLO PAVONE MICHELE PAVONE-MACALUSO 《The Journal of urology》1998,159(4):1187-1191
Purpose
We asses the results of bladder preservation for infiltrating cancer. The potential for neoadjuvant chemotherapy followed by extensive transurethral resection and radiotherapy was evaluated in 40 patients with T2-T4a G2-G3 bladder carcinoma.Materials and Methods
From 1983 to 1995, 40 patients with bladder cancer underwent bladder sparing treatment, consisting of neoadjuvant chemotherapy, extensive transurethral resection and radiotherapy. Most patients had T3G3 cancer. A deep transurethral resection biopsy was performed before and after chemotherapy, and an extensive transurethral resection was repeated at the end of radiotherapy. Of the patients 30 received cisplatin and methotrexate and 10 also received vinblastine. Total dose of radiotherapy was 60 to 65 Gy. Recurrent superficial tumors were treated transurethrally. Radical cystectomy was considered for persistent or recurrent invasive disease.Results
Complete response occurred in 19 patients (47.5%) after chemotherapy, and in 8 patients after transurethral resection and radiotherapy (67.5%). Within 10 years 8 responding patients (30%) had local recurrences and 3 underwent cystectomy. Of the patients 14 (35%) are alive, including 13 with no evidence of disease (mean survival 65 months), 5 died of unrelated disease and 21 (52.5%) died of distant metastases (mean survival 28 months). Of the 21 patients 14 had residual tumor after radiotherapy, 3 presented with distant metastases after vesical infiltrating recurrence and 4 had distant metastases in the absence of locoregional recurrence. In 22 patients (55%) the bladder was salvaged. Patients with complete response to chemotherapy had a low risk for recurrent infiltrating tumors and metastases.Conclusions
Complete tumor control was maintained at 5 years in more than 50% of the patients treated conservatively. Bladder salvage is feasible in select patients. 相似文献28.
VINCENZO DONADIO GIUSEPPE PLAZZI STEFANO VANDI CHRISTIAN FRANCESCHINI TOMAS KARLSSON PASQUALE MONTAGNA ROBERTO VETRUGNO ENRICO BUGIARDINI EMMANUEL MIGNOT ROCCO LIGUORI 《Journal of sleep research》2008,17(4):458-463
Autonomic nervous system activity changes have been described during cataplexy as playing a role in triggering it. To confirm these previous findings, we investigated the time course of sympathetic and cardiovascular activities during cataplexy. We made for the first time microneurographic recordings of 10 cataplectic episodes in three patients with hypocretin‐deficient narcolepsy. During microneurography, muscle sympathetic nerve activity (MSNA) was recorded simultaneously with heart rate (HR), respiratory movements, arterial finger blood pressure (BP), electroencephalography, electro‐oculogram and superficial electromyogram. Results showed no significant autonomic changes before the onset of the cataplectic episodes. Cataplexy was associated with a significant increase in MSNA and BP compared with baseline, whereas HR was markedly decreased. An irregular breathing pattern mainly characterized by apnea typically occurred during the attacks. In conclusion, our findings did not show significant changes in autonomic activity prior to cataplexy onset, ruling out a triggering role of the autonomic system. However, cataplexy was associated with co‐activation of sympathetic and parasympathetic autonomic systems, a pattern reminiscent of that reported during the vigilance reaction in animals. 相似文献
29.
Substrate Ablation in Treatment of Atrial Fibrillation 总被引:2,自引:0,他引:2
CARLO PAPPONE M.D. PH.D. F.A.C.C. VINCENZO SANTINELLI M.D. 《Journal of cardiovascular electrophysiology》2006,17(S3):S23-S27
From the time catheter ablation of atrial fibrillation (AF) was first reported, of the two dominant approaches for AF ablation, only pulmonary vein (PV) isolation has been modified, while circumferential pulmonary vein ablation (CPVA) as performed by our group in Milan has remained substantially unmodified. In fact, PV isolation as initially performed by Haissaguerre et al. has undergone rapid evolution toward substrate modification with significantly higher success rates without major complications. Modification of such technique was due to modification of the substrate. It is now evident that substrate modification is indeed crucial for curing AF particularly in patients with long-lasting or permanent AF. Indeed, to achieve good outcomes, any ablation technique should simultaneously include elimination of all triggers associated with modification of both anatomic and autonomic substrate, as we started to do many years ago by performing CPVA. 相似文献
30.