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991.
H Yerli E Aydin N Haberal A Harman T Kaskati S Alibek 《Dento maxillo facial radiology》2010,39(6):349-355
Objectives
The purpose of this study was to evaluate the accuracy of MRI combined with diffusion-weighted imaging (DWI) vs fine-needle aspiration cytology (FNAC) in diagnosing common parotid masses.Methods
25 consecutive patients (mean age 61 years) with parotid masses were included in this study. Informed consent and ethical approval was obtained. 22 patients underwent both MRI combined with DWI and FNAC. From DWI data, apparent diffusion coefficient maps were generated. The MRI study protocol consisted of T1 weighted spin echo; T2 weighted and T2 weighted fat-suppressed turbo spin echo; DWI; and T1 weighted fat-suppressed post-contrast images. MRI and FNAC diagnoses were compared with histopathology. Youden''s index was used to compare the two methods.Results
Masses comprised eight Warthin tumours, eight adenomas (six pleomorphic adenomas, two basal cell adenomas), five carcinomas, two lipomas, one haemagioma and one benign lymphadenopathy. Technically, MRI was successful in 24 of the 25 patients (96%), FNAC was successful in 20 of the 23 patients (87.0%). The accuracy, sensitivity and specificity of MRI without DWI were 96%, 80% and 100%, respectively. Diagnostic accuracy did not increase by adding DWI to conventional MRI; however, DWI was helpful for diagnosing benign tumour histology. MRI combined with DWI was successful for determining accurate tumour typing in all benign masses except one lymphadenopathy. When FNAC had adequate material the accuracy, sensitivity and specificity were 95%, 75% and 100%, respectively. Youden''s index was 0.80 for MRI and 0.75 for FNAC.Conclusions
MRI combined with DWI seems to have similar diagnostic potential as FNAC in differentiation of benign vs malignant parotid masses. 相似文献992.
Mutlu Dogan Lutfi Dogan Feyyaz Ozdemir Nuriye Yildirim Ozdemir Hasan Senol Coskun Ulku Yalcintas Arslan Guze Ozal Gungor Utkan Ahmet Demirkazik Fazil Aydin Nurullah Zengin Fikri Icli 《Clinical & translational oncology》2010,12(9):629-633
Introduction
Kaposi sarcoma (KS) is a mesenchymal tumor originating from lymphatic endothelial cells. Immunsupressive patients have higher risk for KS. HHV-8 has a role in immunpathogenesis of KS.Aim
Evaluation of demographical properties with tumor characteristics and treatment modalities of KS.Material and method
Histopathologically documented KS patients were evaluated retrospectively. Anti-HIV seroprevalence was also evaluated with patient and tumor characteristics besides treatment regimens.Results
Fifty-one patients were included between September 1998 and February 2009. Male/female ratio was 3.25 (39/12). Median age was 68 (31–94). Lower extremity was the most common site whereas excisional biopsy was the most common diagnostic procedure. Smoking rate was 42.8%. Twenty percent had family history for cancer. Anti-HIV seropositivity rate was 1.9%. Thirty eight percent had local monotherapy, and radiotherapy was most common (26%). Multidisciplinary approach rate was 44%. Most of them had surgery and radiotherapy combination. Two-third of the patients had radiotherapy alone or with other modalities. Rates were as 12% for chemotherapy and 6% for interferon. Vincristine-bleomycin-doxorubicin combination was the most preferred regimen (60%).Conclusion
Male patients in the sixth decade seem to have higher risk for KS. Smoking rate was almost as high. Local therapy might be sufficient in most of the patients. However, we may also consider systemic chemotherapy for selected patients, including vincristine, bleomycin and doxorubicin. 相似文献993.
Ozer Makay Mircelal Kazimi Unal Aydin Deniz Nart Funda Yilmaz Murat Zeytunlu Erdem Goker Ahmet Coker 《International journal of clinical oncology / Japan Society of Clinical Oncology》2010,15(1):88-92
Pancreatic lipomatosis is characterized as massive lipid infiltration of the pancreatic tissue. Although its etiology is ill
defined; obesity, diabetes mellitus, chronic pancreatitis, hereditary pancreatitis, and conditions that cause pancreatic ductal
obstruction, for example tumors and stones, are related to its pathogenesis. Recently, with the increased use of computerized
tomography and magnetic resonance imaging, it has
become possible to observe the fat replacement of the pancreas. Herein, we report a 60-year-old man complaining of abdominal
pain and weight loss. Preoperative work-up revealed a locally advanced (Stage III) pancreatic adenocarcinoma. Multimodal treatment
was carried out and a 100% complete response was detected after neoadjuvant therapy. The patient underwent a standard pancreaticoduodenectomy,
without complications. The tissue pathology revealed lipomatosis of the pancreas. He was disease-free and symptom-free at
1 year follow-up. To our knowledge, this is the first report in the literature of pancreatic head carcinoma with total fat
replacement of the pancreas after neoadjuvant chemoradiotherapy. 相似文献
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A meningoencephalocele is a herniation of meninges and brain out of the cranial fossa through a bony defect. Cerebrospinal fluid leakage may occur due to a defect in the wall of the meningoencephalocele. The defect may be traumatic, iatrogenic, or may appear spontaneously. In this report, the authors present an unrecognized transethmoidal meningoencephalocele that resulted in a cerebrospinal fluid leak during dacryocystorhinostomy. 相似文献
1000.
Aydin B Cagil N Erdoğan S Erdurmus M Hasiripi H 《Journal of cataract and refractive surgery》2008,34(8):1280-1287
PURPOSE: To evaluate the effectiveness and therapeutic range of laser-assisted subepithelial keratectomy (LASEK) without mitomycin-C (MMC) to treat high myopia. SETTING: Isik Eye Clinic, Ankara, Turkey. METHODS: This study comprised 31 highly myopic eyes (19 patients) that had LASEK. Before primary LASEK treatment and 1, 3, 6, 12, and 24 months after, all patients had a complete ophthalmic examination including visual acuity, refractive outcomes, and biomicroscopy. RESULTS: The mean spherical equivalent (SE) was -9.01 diopters (D) +/- 2.66 (SD) preoperatively and -1.00 +/- 1.15 D at the end of follow-up. At 24 months, the mean SE was within +/-1.00 D of the intended correction in 23 eyes (74.19%). The median uncorrected visual acuity (UCVA) increased from 20/606 preoperatively to 20/28.6 at 24 months and the median best corrected visual acuity, from 20/25 to 20/22, respectively. Total higher-order and spherical aberrations increased significantly at the end of follow-up. All 14 eyes that had ablations greater than -8.62 D developed varying degrees of haze. Significant myopic regression (>1.00 D) leading to UCVA loss occurred in all eyes with a preoperative SE of -12.00 D or greater. CONCLUSIONS: The results of LASEK without MMC were excellent in eyes with up to -8.6 D of SE. All eyes with a preoperative SE between -8.6 and -12.0 D developed haze but had acceptable refractive and visual outcomes. Haze and myopic regression limited the success of LASEK in eyes with a preoperative SE of -12.0 D and greater. 相似文献