Aortic distensibility and coronary artery bypass graft patency

Background  

Aortic distensibility is an elasticity index of the aorta, and reflects aortic stiffness. Coronary artery disease has been found to be substantially associated with increased aortic stiffness. In this study we aimed to retrospectively analyze the association of angiographically determined aortic distensibility with the patency rates of coronary bypass grafts     

Is femoral trochlear dysplasia related to global joint hypermobility?

BackgroundHypermobility is a known risk factor for patellar instability. In this study, we hypothesized that a significant relationship exists between global joint hypermobility and trochlear dysplasia.MethodsFollow-up patients from the shoulder department of our institution with global joint hypermobility (Group 1, n = 42) and healthy volunteers (Group 2, n = 42) without known knee complaints were included in our study. All participants underwent knee magnetic resonance imaging (MRI) for the evaluation of possible trochlear dysplasia, and the measurements included lateral trochlear inclination; trochlear facet asymmetry; the depth of the trochlear groove; condylar asymmetry; lateralization of the patella; sulcus angle; and the lateral, medial and central trochlear height. The Dejour classification was also assessed.ResultsThe age and gender distributions of the groups were similar (p > 0.05). The radiological evaluations revealed that the lateral trochlear inclination (p < 0.001), trochlear facet asymmetry (p < 0.001), depth of the trochlear groove (p < 0.001), lateralization of the patella (p < 0.001), sulcus angle (p < 0.001), and central trochlear height (p < 0.001) were significantly different between the two groups. The condylar asymmetry and lateral and femoral condylar height parameters were similar between the groups (p = 0.297, p = 0.890 and p = 0.521, respectively). According to the Dejour classification, 39 patients had dysplasia in Group 1, whereas dysplasia was detected in only 4 of the participants in Group 2.ConclusionsOur study revealed that most of the trochlear dysplasia criteria were met in patients with global joint hypermobility. In addition to a clinical patellofemoral examination, the precise radiological evaluation of the joint is beneficial in patellofemoral instability patients with concomitant hypermobility. Patient cohort of this study was consist of patients underwent shoulder surgery.     

Recurrent mucinous cystadenoma: a laparoscopic approach

The second most common epithelial tumor of the ovary is mucinous-type, and it constitutes 8–10% of all ovarian tumors. The recurrence of mucinous cystadenoma is very rare after complete excision. Only four such cases have been reported till date. The case presented in this report is the fifth, who had her initial surgery performed by gynecologic oncology team by laparotomy and was followed up by the same group. After recurrence at the same ovary, the patient underwent laparoscopic evaluation and unilateral salpingoophorectomy was performed. The final histopathological diagnosis was mucinous cystadenoma, just the same as the initial cyst.     

Apparent diffusion coefficient in differentiation of pediatric posterior fossa tumors

Purpose

To investigate the contribution of preoperative apparent diffusion coefficient (ADC) values in the differential diagnosis of pediatric posterior fossa tumors.

Methods

Forty-two pediatric patients (mean age 7.76 ± 4.58 years) with intra-axial tumors in the infra-tentorial region underwent magnetic resonance imaging. ADC measurement was performed using regions of interest, obtained from the solid component of the mass lesions. ADC ratios were calculated by dividing the ADC values from the mass lesions by the ADC values from normal cerebellar parenchyma. Lesions were categorized as juvenile pilocytic astrocytoma (JPA), ependymoma and medulloblastoma based on histopathological diagnosis. ADC values of the lesions and histopathological diagnoses were statistically correlated.

Results

Histopathological diagnosis showed that 14 lesions were JPA, 10 were ependymoma; 18 were medulloblastoma. Both ADC values and ADC ratios were significantly correlated with tumor types (p <0.05). Astrocytoma was distinguished from ependymoma with sensitivity 85.7% and specificity 90% using an ADC ratio ≥1.7 and medulloblastoma was distinguished from ependymoma with sensitivity 100% and specificity 88.89% using an ADC ratio ≤1.18.

Conclusion

Preoperative ADC values could differentiate the main histological subtypes of pediatric posterior fossa tumors with high sensitivity and specificity.

     

Meningeal solitary fibrous tumor: report of a case and literature review

Solitary fibrous tumor is a rare neoplasm that most often involves the pleura. The increasing numbers of this neoplasm have also been reported to date in extrapleural sites. We report a case of a twenty-four-year-old female with right frontal mass. Histologically, the tumor composed of spindle cell proliferation. Tumor cells were found to be positive for CD34 and CD117 with immunohistochemical studies. Ten months follow-up was uneventful. Seventy seven cases of meningeal solitary fibrous tumor from the literature are analysed and pathological, immunohistochemical and clinical features are discussed. Solitary fibrous tumor has a slight female predominance, with a male to female ratio of 1:1.5. Age distribution is similar to meningioma ranging from 7-81 years. Approximately 23% of cases originate in the spine which is the most common meningeal location. Histopathologic examination shows uniform spindle cell proliferation with various amount of collagen. CD34-positivity usually allows discrimination from schwannomas, meningiomas and hemangiopericytomas. A differential diagnosis is important because most of the solitary fibrous tumors usually behave in a benign fashion. In this study, we also showed CD117 (Kit) expression in a case of meningeal SFT. CD117-positivity can be a good strategy for treatment in malignant and recurrent cases. Further investigations are necessary for therapeutic implication of CD117-positivity in SFT.     

The Turkish version of the Bath Ankylosing Spondylitis Functional Index: reliability and validity

The purpose of this study was to investigate the reliability and validity of the Turkish version of the Bath Ankylosing Spondylitis (AS) Functional Index (BASFI). The Turkish version of the BASFI was obtained after a process of translation and back-translation. Eighty-one consecutive patients meeting the 1984 New York criteria for AS were enrolled. Patients were evaluated and requested to complete the questionnaire at days 1 and 2 and on a third occasion between days 15–90. Reliability, reproducibility, validity and sensitivity to change of the Turkish version of the index were assessed. Each score correlated closely with the index score, with coefficients between 0.727 and 0.844. Reliability analysis showed a Cronbachs alpha score of 0.926. Correlations were found between all items of the BASFI and Schobers test (r=–0.258 to –0.531, p<0.001–0.05), occiput-to-wall distance (r=0.284 and 0.589, p<0.001–0.05), and finger-to-floor distance (r=0.334 to 0.613, p<0.001–0.01). The total index score was correlated with the number of nocturnal awakenings (r=0.515, p<0.001), Schobers test (r=–0.444, p<0.001), finger-to-floor distance (r=0.567, p<0.001), occiput-to-wall distance (r=0.535, p<0.001), chest expansion (r=–0.403, p<0.001), and the Dougados articular index (r=0.371, p<0.01). A good correlation was found between day 0 and 1 BASFI indices (r=0.765–0.917, p<0.001), showing good reproducibility of the index. The Turkish version of the BASFI showed reliability, reproducibility, and validity, confirming its utility in the research of AS in Turkey. However, sensitivity to changes due to drug therapy and/or rehabilitation remains to be determined.     

Evaluation of the Turkish version of the Dougados functional index in ankylosing spondylitis

To investigate the reliability and validity of the Turkish version of the Dougados functional index (DFI) in patients with ankylosing spondylitis (AS). The Turkish version of DFI was obtained after a translation and back-translation process. Seventy consecutive patients with AS were enrolled. Patients were requested to complete the questionnaire on the day of admission (first visit), a second time within 24 h after admission (second visit), and on a third occasion. Reliability, validity and reproducibility of the Turkish version of the index were assessed. All the items showed significant correlations with the total index score with r-values ranging from 0.516 to 0.817. Cronbach score was calculated as 0.908. Significant correlations were found between the total DFI score and Schober test (r=–0.293, P<0.05), occiput-wall distance (r=0.384; P<0.01) finger-to-floor distance (r=0.450, P<0.001), chest expansion (r=–0.331, P<0.01) and Dougados articular index (r=0.352, P<0.05). Good correlations were found between individual DFI items and the total score (r=between 0.533 and 0.882, p< 0.001) for the first and second visits, showing good reproducibility of the index. Conclusion: the Turkish version of DFI has good reliability, validity and reproducibility, confirming its utility for trials in Turkish AS patients.     

Primary cardiac angiosarcoma with right coronary-to-right atrium fistula

Primary tumours of the heart are rare. About 25% of all cardiac tumours are malignant and the most common of these is the angiosarcoma. We present a 61-year-old male with a right atrial angiosarcoma that was detected on coronary angiography. The tumour showed marked vascularity and a right coronary-to-right atrium fistula, and the patient underwent surgical resection. Pathological examination of the tumour was consistent with a cardiac angiosacoma and the diagnosis was also confirmed by immuno-histochemistry. He consequently underwent chemotherapy, however the patient died 60 days after the surgery.