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101.
Yoshitaka Maeda Sayaka Yoshida Toshiyuki Hirai Tomoki Kawasaki Tamaki Kuyama 《Journal of Rural Medicine》2013,8(1):171-175
Objective: The usefulness of estimated glomerular filtration rate may not be
restricted to pre-dialysis patients, since we reported that estimated glomerular
filtration rate was well correlated with measured total creatinine clearance in peritoneal
dialysis patients. To clarify the clinical usefulness of estimated glomerular filtration
rate as a parameter for peritoneal dialysis adequacy, we retrospectively surveyed
estimated glomerular filtration rate and total creatinine clearance in peritoneal dialysis
patients treated at JA Toride Medical Center.Patients and Methods: A total of 114 data sets of estimated glomerular
filtration rate and total creatinine clearance from 21 PD patients treated at JA Toride
Medical Center were collected from November 2010 to October 2011. The patients consisted
of 15 men and six women with an average age of 66.6 ± 12.6 years (46–95 years old). The
average number of samples was 5.4 ± 1.5 (2 to 7) per patient.Results: The collected data showed less correlation of estimated glomerular
filtration rate and total creatinine clearance (r. = 0.435) than that of a previous
cross-sectional study (r. = 0.836). As reported in pre-dialysis patients, the differences
between estimated glomerular filtration rate and total creatinine clearance were
correlated with total creatinine excretion in urine and PD effluent (r. = 0.821). The
differences were also correlated with normalized protein catabolic rate, which was one of
the main determinant factors for total creatinine excretion (r. = 0.636). A similar
tendency was apparently observed in one patient with poor compliance to diet therapy and
fluctuating dietary intake. From the analysis of these data, serum creatinine seemed to
fluctuate less possibly due to compensatory capacity of the residual renal function in
small solute clearance.Conclusions: Consequently, estimated glomerular filtration rate was turned
out to be a more stable parameter than total creatinine clearance, which might be a
desirable feature in long-term follow-up of peritoneal dialysis patients. 相似文献
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Takuya HASEGAWA Chiyoe MURATA Takashi NINOMIYA Tomoko TAKABAYASHI Tatsuya NODA Shinya HAYASAKA Mieko NAKAMURA Toshiyuki OJIMA 《Industrial health》2013,51(5):490-500
Problem drinking is a serious public health problem in the workplace. However, few
Japanese epidemiological studies have investigated the occupational characteristics of
problem drinking. The purpose of this study is to clarify the occupational risk factors
for problem drinking among a Japanese working population. We used data from a
random-sampling survey about mental health and suicide, conducted among Hamamatsu City
residents aged 15 to 79 yr old during May and June in 2008. The relation between
occupational factors and problem drinking was analyzed with multiple logistic regression
models stratified by gender. CAGE questionnaire was used to assess problem drinking. With
regard to employment types, problem drinkers were more prevalent among self-employed
women. With regard to occupational types, clerical and service professions had more
problem drinkers of either sex, while administrative/managerial and sales professions had
more women with such problem. With regard to company size, male problem drinkers were more
prevalent in smaller companies than in larger ones. These results indicate that the
prevalence of problem drinkers in the workplace depends on where one works. It is
necessary to consider these characteristics to provide effective measures to address
problem drinking in the workplace. 相似文献
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108.
Neonatal lupus erythematosus (LE) is a rare immune-mediated disease caused by placental transport of maternal anti-SSA/Ro, anti-SSB/La and/or anti-U1RNP antibodies. Here, we demonstrate two cases of neonatal LE, in both of which cutaneous LE was exacerbated by inoculation. To our knowledge, cases worsening neonatal LE after administration of vaccines have not been reported. In case 1, not only exacerbation of pre-existing annular erythema but also spreading of new erythematous lesions to the trunk and extremities were induced following vaccination. Of interest, all of the lesions simultaneously improved. By contrast, in case 2, pre-existing facial erythema became prominent without spreading to other sites. The mother of case 1 had Sjögren’s syndrome, whereas in case 2, the mother was diagnosed with Sjögren’s syndrome on this occasion for the first time. Immunohistochemistry in case 1 revealed interleukin (IL)-17-positive cells infiltrating into the papillary dermis, and CD123-positive plasmacytoid dendritic cells in the papillary dermis and the deep reticular dermis. Both innate immune response and IL-17 mediated inflammation following vaccination are speculated as a possible mechanism of the deterioration of LE lesions in our juvenile cases. Caution is necessary since neonatal LE can be worsened following vaccination. 相似文献
109.
Junya Sakamoto Yoshitaka Manabe Joichi Oyamada Hideki Kataoka Jiro Nakano Kazunobu Saiki Keishi Okamoto Toshiyuki Tsurumoto Minoru Okita 《Clinical anatomy (New York, N.Y.)》2018,31(5):705-709
Introduction : Referred pain in the anterior knee joint is the most common symptom in hip disease patients. The development of referred pain is considered to be related to dichotomizing peripheral sensory fibers. However, no gross anatomical findings identify any dichotomizing fibers innervating both the hip and knee joints. We dissected the femoral and obturator nerves in human cadavers to investigate the distribution of the articular branches in the hip and knee joints. Fourteen embalmed left lower limbs from 14 Japanese adult cadavers (five from females, nine from males, average age 73.8 ± 14.1 years) were observed macroscopically. The articular branches of the femoral and obturator nerves were dissected at the anterior margin of the groin toward the thigh region. After dissections of the articular nerves of the hip joints, the femoral and obturator nerves were exposed from proximally to distally to identify the articular nerves of the knee joints. The branching pattern of the articular branches in the hip and knee joints was recorded. In six of 14 limbs (42.9%), the femoral nerve supplied articular branches to the anteromedial aspect of both the hip and knee joints. These articular branches were derived from the same bundle of femoral nerve. These gross anatomical findings suggested that dichotomizing peripheral sensory fibers innervate the hip and knee joints and these could relate to the referred pain confirmed in the anterior knee joints of patients with hip disease. Clin. Anat. 31:705–709, 2018. © 2018 Wiley Periodicals, Inc. 相似文献