全文获取类型
收费全文 | 207篇 |
免费 | 2篇 |
国内免费 | 6篇 |
专业分类
儿科学 | 2篇 |
基础医学 | 23篇 |
口腔科学 | 7篇 |
临床医学 | 19篇 |
内科学 | 54篇 |
皮肤病学 | 2篇 |
特种医学 | 6篇 |
外科学 | 79篇 |
综合类 | 1篇 |
预防医学 | 3篇 |
眼科学 | 1篇 |
药学 | 15篇 |
肿瘤学 | 3篇 |
出版年
2023年 | 3篇 |
2022年 | 2篇 |
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 5篇 |
2017年 | 2篇 |
2016年 | 3篇 |
2015年 | 5篇 |
2014年 | 6篇 |
2013年 | 10篇 |
2012年 | 9篇 |
2011年 | 21篇 |
2010年 | 18篇 |
2009年 | 15篇 |
2008年 | 13篇 |
2007年 | 25篇 |
2006年 | 14篇 |
2005年 | 13篇 |
2004年 | 4篇 |
2003年 | 9篇 |
2002年 | 1篇 |
2001年 | 3篇 |
2000年 | 4篇 |
1999年 | 2篇 |
1998年 | 2篇 |
1997年 | 3篇 |
1996年 | 2篇 |
1995年 | 1篇 |
1991年 | 1篇 |
1989年 | 2篇 |
1988年 | 1篇 |
1982年 | 2篇 |
1978年 | 1篇 |
1975年 | 1篇 |
1974年 | 1篇 |
排序方式: 共有215条查询结果,搜索用时 15 毫秒
51.
Michael Safioleas Evangelos P. Misiakos Theodosios Dosios Christine Manti Panagiota Lambrou Gregory Skalkeas 《World journal of surgery》1999,23(11):1181-1185
Lung is the second most common site for hydatid disease after the liver. The aim of this study is to present the clinical
symptomatology, diagnostic evaluation, and surgical techniques for the treatment of lung hydatid disease. During the last
25 years, 42 patients with lung hydatid cysts were treated surgically in our department. In four patients there were cysts
in the liver and in one case in the spleen. The cysts were located in the right lung in 16 patients (38%), in the left lung
in 23 patients (54.8%), and in both lungs in 3 patients (7.14%). Eighteen patients (42.9%) presented with complications: suppuration
in one patient (2.4%), rupture to the bronchial tree in 16 patients (38%), and pneumothorax in one patient (2.4%). Diagnosis
was established preoperatively in all cases; chest radiography and computed tomography were most helpful for diagnosis. Forty-six
operations were performed in 42 patients; three patients with bilateral cysts underwent staged thoracotomies, and one patient
was reoperated for recurrent disease. All cases were managed surgically, with several types of radical (34 cases) or conservative
(12 cases) procedures. Radical procedures were lobectomy and rarely pneumonectomy, which were used more often during the first
half of the study period. Cystectomy with capitonnage, the most commonly performed conservative procedure, was mainly used
during the second half of the study period. Postoperative morbidity was 15.2% and the 30-day mortality rate was 0%. In one
case there was postoperative hemorrhage that required reexploration. The median hospital stay for uncomplicated cases was
12 days and for complicated cases 21 days. In conclusion, pulmonary hydatidosis often presents with complications requiring
emergency surgery. A lung-conserving operation is the treatment of choice for lung hydatid disease and offers a good surgical
outcome with a minimal recurrence rate. 相似文献
52.
Ioannis Vassiliou Nikolaos Arkadopoulos Vaia Stafyla Kassiani Theodoraki Anneza Yiallourou Theodosios Theodosopoulos George Kotis George Fragoulidis Thomas Kotsis Vassilios Smyrniotis 《Journal of Hepato-Biliary-Pancreatic Surgery》2009,16(4):552-556
Background/Purpose In major hepatectomies, postoperative increases in central venous pressure (CVP) may cause suture failure and massive bleeding.
The aim of our study is to test the application of an intraoperative maneuver to reduce the risk of postoperative bleeding.
Methods Our study included 172 consecutive patients who had major liver resection with selective hepatic vascular exclusion and sharp
transection of the liver parenchyma. An intraoperative maneuver (5 s occlusion of the hepatic vein) was applied in an alternating
way, and the patients were assigned to two groups: Cohort A (n = 86), that was granted the maneuver, and Cohort B (n = 86), that was used as a control group.
Results In Cohort A, application of the maneuver was successful in demonstrating bleeders under low CVP levels. Cohort A had lower
rate of massive bleeding requiring emergency reoperation (2.3 vs 5.8%, P = 0.049), less postoperative blood transfusions (13 vs 24%, P = 0.042), lower morbidity (20 vs 35%, P < 0.045) and shorter hospital stay compared to Cohort B.
Conclusions Hepatectomies conducted under low CVP are prone to postoperative hemorrhage which can be prevented if the final bleeding control
is performed under high pressure in the hepatic veins. Application of our testing maneuver effectively unmasked previously
undetectable bleeding veins. 相似文献
53.
Diaphragm Myoplasty in the Prevention of Complications after Surgery of Hydatid Disease of the Liver
Abstract
A variety of techniques have been used for surgical treatment of hepatic hydatid cysts. The objective of this study is to
describe the technique of diaphragm myoplasty, and to present our experience in the treatment of selected patients with hydatid
disease of the liver by means of this alternative surgical technique. The technique combines a diaphragm myoplasty with a
wide partial cystectomy performed through a right thoracophrenotomy incision. The medical records of the patients with hydatid
disease of the liver who were submitted to surgical treatment with this technique were reviewed. The clinical manifestations,
laboratory examinations, operative notes, and postoperative results were analyzed. Eight consecutive patients with hepatic
hydatid cyst were operated on. The cyst was located in the posterior-superior aspect of the right hepatic lobe in all patients.
Five patients suffered from recurrence of a previously operated hepatic hydatid cyst, and two patients suffered from complications
of their disease. There was no in-hospital mortality or morbidity. The early and late postoperative results compare favorably
with the results of other investigators. The alternative surgical technique for treatment of selected patients with hepatic
hydatid disease is indicated for patients with a cyst located in the posterior-superior aspect of the right hepatic lobe,
especially if there is a recurrence of the disease after a previous surgery or involvement of the diaphragm and/or the intrathoracic
organs. The technique provides easy and safe access to the cyst and carries most of the advantages of omentoplasty. 相似文献
54.
Nikolaos Arkadopoulos Vaia Stafyla Athanasios Marinis Vassilios Koutoulidis Kassiani Theodoraki Theodosios Theodosopoulos Ioannis Vassiliou Nikolaos Dafnios Georgios Fragulidis Vassilios Smyrniotis 《World journal of gastroenterology : WJG》2009,15(3):339-343
AIM: To test whether clamping during liver surgery predisposes to hepatic vein thrombosis. METHODS: We performed a retrospective analysis of 210 patients who underwent liver resection with simultaneous inflow and outflow occlusion. Intraoperatively, flow in the hepatic veins was assessed by Doppler ultrasonography during the reperfusion phase. Postoperatively, patency of the hepatic veins was assessed by contrast-enhanced CT angiography, when necessary after 3-6 mo follow up. RESULTS: Twelve patients (5.7%) developed intraoperative liver remnant swelling. However, intraoperative ultrasonography did not reveal evidence of hepatic vein thrombosis. In three of these patients a kinking of the common trunk of the middle and left hepatic veins hindering outflow was recognized and was managed successfully by suturing the liver remnant to the diaphragm. Twenty three patients (10.9%) who developed signs of mild outflow obstruction postoperatively, had no evidence of thrombi in the hepatic veins or flow disturbances on ultrasonography and contrast-enhanced CT angiography, while hospitalized. Long term assessment of the patency of the hepatic veins over a 3-6 mo follow-up period did not reveal thrombi formation or clinical manifestations of outflow obstruction. CONCLUSION: Extrahepatic dissection and clamping of the hepatic veins does not predispose to clinically important thrombosis. 相似文献
55.
56.
57.
Chamogeorgakis T Anagnostopoulos C Kostopanagiotou G Bhora F Toumpoulis I Georgiannakis E Nabong A Dosios T Harrison L Connery C 《The Thoracic and cardiovascular surgeon》2008,56(3):148-153
BACKGROUND: Preoperative anemia has been shown to be an ominous prognostic factor for survival in patients with early stage non small cell lung cancer. METHODS: Two hundred and fourteen patients underwent resection for early stage non small cell lung cancer between 2001 and 2006 without neo-adjuvant treatment. Patients were divided into four groups based on their admission hemoglobin (Hgb): group I: Hgb < or = 12 g/dl, group II: Hgb = 12.1 - 12.9 g/dl, group III: Hgb = 13.0 - 14.0 g/dl, and group IV: Hgb > 14 g/dl. Cox regression analysis was used to evaluate each variable's impact on midterm survival taking all causes and lung cancer-specific mortality into account. Kaplan-Meier survival plots were estimated. RESULTS: Preoperative hemoglobin (HR = 1.44, 95 % confidence intervals 1.08 - 1.94, P = 0.014) and pneumonectomy (HR = 3.58, 95 % confidence intervals 1.26 - 10.16, P = 0.017) were the only predictors of all-cause midterm mortality. Similarly, when only lung cancer-related mortality was considered, preoperative hemoglobin (HR = 1.81, 95 % confidence intervals 1.17 - 2.78, P = 0.007) and pneumonectomy (HR = 6.89, 95 % confidence intervals 2.29 - 20.73, P = 0.001,) were independent predictors. Age, gender, pulmonary function test results, tumor stage, and histology did not influence survival. CONCLUSIONS: Preoperative anemia and the type of resection in early stage non small cell lung cancer have an impact on midterm survival and lung cancer-specific mortality. 相似文献
58.
Vasilis Tsimihodimos Irene Gazi Theodosios Filippatos Michael Kostapanos Kostantinos Lagos Christina Kostara Constantinos C. Tellis Moses Elisaf Alexandros D. Tselepis 《Atherosclerosis》2010,208(2):506-511
ObjectiveExperimental studies have shown that the preβ-1 subclass of high-density lipoprotein particles (preβ-1 HDL) may play an important role in the reverse cholesterol transport pathway as the initial acceptors of cellular cholesterol. The aim of the present study was the direct comparison of preβ-1 HDL values in individuals with various types of primary dyslipidemias.MethodsFour hundred and eighty-six unrelated individuals were included in the study. According to their lipid values study participants were subdivided into four groups: control group (n = 206), type IIA dyslipidemia group (n = 148), type IIB dyslipidemia group (n = 49) and type IV dyslipidemia group (n = 83).ResultsAll dyslipidemic patients displayed higher concentrations of preβ-1 HDL compared to control individuals. However, patients with dyslipidemias characterized by an abnormal catabolism of triglyceride-rich lipoproteins (such as dyslipidemias of type IIB and IV) tend to have higher preβ-1 HDL values compared to patients with hypercholesterolemia, and this increase is proportional to the degree of hypertriglyceridemia. In addition, patients with metabolic syndrome exhibited significantly higher levels of preβ-1 HDL compared to individuals that do not fulfill the criteria for the diagnosis of this syndrome. Multiple regression analysis revealed that serum triglyceride concentrations and body mass index (BMI) values were the most important determinants of preβ-1 HDL levels in our population.ConclusionAll dyslipidemic patients exhibit increased preβ-1 HDL concentrations as compared to normolipidemic individuals. Whether this increase represents a defensive mechanism against atherosclerosis or it is indicative of impaired maturation of HDL particles and thus of a defective reverse cholesterol transport mechanism remains to be established. 相似文献
59.
60.