全文获取类型
收费全文 | 955篇 |
免费 | 94篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 106篇 |
儿科学 | 38篇 |
妇产科学 | 8篇 |
基础医学 | 80篇 |
口腔科学 | 11篇 |
临床医学 | 44篇 |
内科学 | 124篇 |
皮肤病学 | 17篇 |
神经病学 | 9篇 |
特种医学 | 101篇 |
外科学 | 232篇 |
综合类 | 63篇 |
预防医学 | 105篇 |
眼科学 | 11篇 |
药学 | 20篇 |
肿瘤学 | 88篇 |
出版年
2022年 | 7篇 |
2021年 | 9篇 |
2020年 | 11篇 |
2019年 | 21篇 |
2018年 | 25篇 |
2017年 | 16篇 |
2016年 | 16篇 |
2015年 | 25篇 |
2014年 | 20篇 |
2013年 | 24篇 |
2012年 | 35篇 |
2011年 | 39篇 |
2010年 | 36篇 |
2009年 | 34篇 |
2008年 | 46篇 |
2007年 | 46篇 |
2006年 | 42篇 |
2005年 | 38篇 |
2004年 | 30篇 |
2003年 | 32篇 |
2002年 | 49篇 |
2001年 | 39篇 |
2000年 | 43篇 |
1999年 | 32篇 |
1998年 | 42篇 |
1997年 | 30篇 |
1996年 | 24篇 |
1995年 | 17篇 |
1994年 | 14篇 |
1993年 | 10篇 |
1992年 | 12篇 |
1991年 | 9篇 |
1990年 | 5篇 |
1989年 | 17篇 |
1988年 | 15篇 |
1987年 | 18篇 |
1986年 | 16篇 |
1985年 | 8篇 |
1984年 | 6篇 |
1983年 | 7篇 |
1982年 | 5篇 |
1981年 | 6篇 |
1980年 | 6篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1976年 | 6篇 |
1975年 | 11篇 |
1969年 | 8篇 |
1967年 | 5篇 |
1962年 | 3篇 |
排序方式: 共有1057条查询结果,搜索用时 0 毫秒
81.
SK Bhattacharya MK Bhattacharya B Manna D Dutta A Deb P Dutta AG Goswami A Dutta S Sarkar A Mukhopadhaya T Krishnan TN Naik GB Nair 《Acta paediatrica (Oslo, Norway : 1992)》1995,84(2):160-164
In a case-control study to understand the risk factors for development of life-threatening dehydration, a total of 379 children comprising 243 cases (moderate or severe dehydration) and 136 controls (non or mild dehydration) up to 2 years of age suffering from acute watery diarrhoea were studied. By univariate analysis, the presence of vibrios in stool, withdrawal of breast feeding during diarrhoea, not giving fluids, including oral rehydration solution (ORS), during diarrhoea, frequent purging (> 8/ day), vomiting (> 2/day) and undernutrition were identified as risk factors. However, by multivariate analysis after controlling for confounders, withdrawal of breast feeding during diarrhoea (odds ratio (OR) = 6.8, p < 0.00001) and not giving ORS during diarrhoea (OR = 2.1, p < 0.006) were identified as significant risk factors. The confounding variables which also contributed significantly to increasing the risk were age (≤ 12 months; OR = 2.7, p = 0.001), frequent purging (> 8/day; OR = 4.1, p < 0.00001), vomiting (> 2/day; OR = 2.4, p = 0.001) and severe undernutrition (%median <60 weight-for-age of Indian Academy of Paediatrics classification; OR = 3.1, p = 0.001). We feel that these findings will be useful for Global and National Diarrhoeal Diseases Control Programmes for formulating intervention strategies for preventing death due to diarrhoeal dehydration. 相似文献
82.
Intracranial abnormalities in infants treated with extracorporeal membrane oxygenation: imaging with US and CT 总被引:1,自引:0,他引:1
Findings at neuroimaging in 100 consecutive infants treated with extracorporeal membrane oxygenation (ECMO) are presented. Imaging in these infants consisted of pretreatment cranial ultrasonography (US), daily US studies while on ECMO, and follow-up cranial computed tomography (CT) after treatment. There were findings of abnormalities in 43 patients. Thirty had intracranial bleeding, often of unusual extent and distribution. Thirteen additional infants had nonhemorrhagic abnormalities alone. Bleeding considered to be major was seen in 12% of infants. Large parenchymal hemorrhages and infarcts, cerebellar hemorrhages, and diffuse edema were the most significant abnormalities, with a 50% mortality (eight of 16 patients). No lateralization was noted with respect to distribution of bleeding sites or areas of nonhemorrhagic abnormalities. US was a sensitive but imperfect screening tool for intracranial abnormalities. Abnormalities missed with US included peripheral and small parenchymal lesions, subarachnoid hemorrhage, cerebral atrophy, and sagittal sinus thrombosis. 相似文献
83.
84.
85.
86.
Determination of prostate volume by transrectal ultrasound 总被引:25,自引:0,他引:25
Estimation of prostate gland volume with transrectal ultrasound may provide important information in the evaluation of benign and malignant prostatic diseases. To determine the most accurate means of volume estimation 150 patients underwent transrectal ultrasound with 15 separate methods of volume estimation. All patients underwent subsequent radical prostatectomy or cystoprostatectomy. Prostate specimen weights were compared with the results of each volume estimation method. Step-section planimetry, previously assumed to be the most accurate means of volume measurement, exhibited a Pearson correlation coefficient of 0.93. The elliptical volume, widely used as an alternative to planimetry, demonstrated a correlation coefficient of 0.90. The most accurate method to estimate prostate weight (r = 0.94) was a variation of the prolate spheroid formula, expressed as pi/6 (transverse dimension)2 (anteroposterior dimension). When different volume ranges were considered, this prolate spheroid formula provided the closest estimate of weight in glands of less than 40 gm. and those in the 40 to 80 gm. range. The most accurate method to estimate prostates weighing greater than 80 gm. was the formula pi/6 (transverse dimension)3. 相似文献
87.
The health status of Cuba: recommendations for epidemiologic investigation and public health policy 总被引:2,自引:0,他引:2
M Terris 《Journal of public health policy》1989,10(1):78-87
The health status of Cuba is described in comparison with Costa Rica and, in some instances, the United States. Recommendations are made for epidemiologic studies and for specific health policies to lower death rates from diarrhea and enteritis, cardiovascular disease, cancer, and injuries. Rapid expansion of training and research in epidemiology and biostatistics is emphasized, and specific goals for health outcomes for the year 2000 are suggested. 相似文献
88.
The incidence of thromboembolitic events in patients undergoing transfemoral angiography was examined using indium-111 labeled platelets. Twenty-seven patients received approximately 300 muCi of autologous labeled platelets at least 3 hours before angiography and were scanned with a gamma camera immediately before and after angiography. All patients were free of clinically obvious complications in the 1-2 day period after angiography. Our results showed evidence of platelet deposition at 21 sites other than the puncture site in 12 (44%) patients. Most platelet deposition (54%) occurred along the region between the puncture site and the aortic bifurcation; 24% occurred at sites not traversed by the catheter. At the puncture site itself, there was substantial platelet uptake in 44% of patients. This study indicates the need for further work in determining the most suitable catheter material and in assessing the efficacy of other measures such as anticoagulant or antiplatelet therapy. 相似文献
89.
True or sham plasma exchange was done weekly for 20 weeks in patients in two of the randomization groups in a prospective, blind clinical trial of experimental treatments for multiple sclerosis. Because patients could be randomized to receive sham plasma exchange and placebo medications, it was decided when the trial was designed that the use of fistulae, arteriovenous shunts, venous cutdowns, or other aggressive forms of venous access would not be permitted for any patient. Accordingly, patients judged to have inadequate superficial antecubital veins were ineligible for the trial. To date, only 13 (4.4%) of 294 patients considered for entry into the trial have been rejected on these grounds. In only 4 of the 93 patients undergoing exchange was it necessary to discontinue plasma exchange because of inadequate venous access. In 79.3 percent of the 1207 exchanges done in these patients, there were no problems of any kind with venous access. In 5.4 percent of these 1207 exchanges, it was necessary to terminate the procedure prematurely because of difficulties with patients' veins. Thus, the great majority of patients free of serious systemic illness (other than chronic progressive multiple sclerosis) can undergo weekly plasma exchange for up to 20 weeks using superficial antecubital veins without the need to resort to more invasive methods of venous access. 相似文献
90.
Arnault TauziedeEspariat Batrice Parfait Aurore Besnard Joëlle Lacombe Johan Pallud Sanaa Tazi Stphanie Puget Guillaume Lot Benoît Terris Joëlle Cohen Michel Vidaud Dominique FigarellaBranger Franck Monnien Marc Polivka Homa AdleBiassette Pascale Varlet 《Brain pathology (Zurich, Switzerland)》2018,28(4):466-474
Clear cell meningioma (CCM) is a rare grade II histopathological subtype that usually occurs in young patients and displays high recurrence rate. Germline SMARCE1 mutations have been described in hereditary forms of this disease and more recently in small syndromic and sporadic CCM series. The diagnostic value of SMARCE1 in distinguishing between CCM and other meningioma variants has not been yet established. The aim of our study was to investigate the status of SMARCE1 in a series of CCMs and its morphological mimickers. We compared the performance of an anti‐SMARCE1 antibody and the molecular analysis of the SMARCE1 gene in a retrospective multicenter series of CCMs. All CCMs lossed SMARCE1 immunoexpression. Bi‐allelic inactivating events were found by NGS‐based sequencing in all of these cases, except for one, which was incompletely explored, but had a wild‐type sequence. We then validated the anti‐SMARCE1 antibody specificity by analyzing additional 305 pediatric and adult meningiomas of various subtypes and 15 non‐meningioma clear cell tumors by SMARCE1 immunohistochemistry. A nuclear immunostaining was preserved in all other meningioma variants, as well as non‐meningioma clear cell tumors. In conclusion, our series showed, for the first time, that SMARCE1 immunostaining is a highly sensitive biomarker for CCM, useful as a routine diagnostic biomarker. 相似文献