全文获取类型
收费全文 | 12048篇 |
免费 | 662篇 |
国内免费 | 61篇 |
专业分类
耳鼻咽喉 | 94篇 |
儿科学 | 196篇 |
妇产科学 | 268篇 |
基础医学 | 1537篇 |
口腔科学 | 175篇 |
临床医学 | 808篇 |
内科学 | 3085篇 |
皮肤病学 | 439篇 |
神经病学 | 815篇 |
特种医学 | 439篇 |
外科学 | 1983篇 |
综合类 | 49篇 |
一般理论 | 3篇 |
预防医学 | 289篇 |
眼科学 | 250篇 |
药学 | 809篇 |
中国医学 | 35篇 |
肿瘤学 | 1497篇 |
出版年
2023年 | 87篇 |
2022年 | 125篇 |
2021年 | 341篇 |
2020年 | 211篇 |
2019年 | 278篇 |
2018年 | 391篇 |
2017年 | 216篇 |
2016年 | 278篇 |
2015年 | 276篇 |
2014年 | 362篇 |
2013年 | 405篇 |
2012年 | 673篇 |
2011年 | 730篇 |
2010年 | 422篇 |
2009年 | 351篇 |
2008年 | 615篇 |
2007年 | 645篇 |
2006年 | 622篇 |
2005年 | 594篇 |
2004年 | 576篇 |
2003年 | 497篇 |
2002年 | 517篇 |
2001年 | 318篇 |
2000年 | 261篇 |
1999年 | 305篇 |
1998年 | 142篇 |
1997年 | 92篇 |
1996年 | 89篇 |
1995年 | 88篇 |
1994年 | 81篇 |
1993年 | 71篇 |
1992年 | 177篇 |
1991年 | 189篇 |
1990年 | 176篇 |
1989年 | 201篇 |
1988年 | 175篇 |
1987年 | 177篇 |
1986年 | 137篇 |
1985年 | 128篇 |
1984年 | 87篇 |
1983年 | 83篇 |
1982年 | 36篇 |
1980年 | 35篇 |
1979年 | 53篇 |
1978年 | 34篇 |
1977年 | 37篇 |
1974年 | 42篇 |
1972年 | 37篇 |
1971年 | 37篇 |
1969年 | 40篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
21.
We report a case of extraadrenal pheochromocytoma of Zuckerkandl imaged by dynamic magnetic resonance imaging (dynamic MRI) with a 0.5 tesla (T) machine. The dynamic MRI proved useful in disclosing the tumor clearly because of strong enhancement in its early phase. This case has the advantages of dynamic computed tomography (dynamic CT) as well as of T2-weighted spin-echo (SE) MR images. 相似文献
22.
Cytokines in bronchoalveolar lavage fluid in patients with high altitude pulmonary oedema at moderate altitude in Japan. 总被引:5,自引:0,他引:5
K. Kubo M. Hanaoka S. Yamaguchi T. Hayano M. Hayasaka T. Koizumi K. Fujimoto T. Kobayashi T. Honda 《Thorax》1996,51(7):739-742
BACKGROUND: The precise mechanism of high altitude pulmonary oedema (HAPE) remains unclear. The purpose of this study was to evaluate the role of cytokines and P-selectin in the development of HAPE which occurred at moderate altitude in Japan. METHODS: The following cellular and biochemical markers and chemotactic cytokines were measured in the bronchoalveolar (BAL) fluid from four patients with HAPE at 2857-3180 m in the Japanese Alps: total proteins, albumin, lactate dehydrogenase (LDH), and interleukin (IL)-1 alpha, IL-1 beta, IL-1 receptor antagonist (ra), IL-6, IL-8, IL-10, tumour necrosis factor (TNF)-alpha, and the soluble form of P-selectin. RESULTS: At admission there were significant increases in the levels of total cells, especially macrophages and neutrophils, total protein, albumin and LDH when compared with 13 healthy individuals. Furthermore, the levels of IL-1 beta, IL-6, IL-8, and TNF-alpha were also considerably increased but returned quickly to the normal ranges or were not detected after recovery. The levels of IL-1 alpha, IL-10, and P-selectin did not change. CONCLUSIONS: These results suggest that an inflammatory process almost identical with acute respiratory distress syndrome (ARDS) may occur in HAPE, but that these changes are transient and are not associated with any increase in P-selectin levels in the BAL fluid. 相似文献
23.
Nobuyuki Takemura Yasuhiko Sugawara Takuya Hashimoto Nobuhisa Akamatsu Yoji Kishi Sumihito Tamura Masatoshi Makuuchi 《Liver transplantation》2005,11(3):356-360
The incidence of hepatic venous stenosis is higher in partial liver transplantation. New methods for hepatic venous reconstruction in left liver transplantation, which secure wide anastomosis, were devised and are reported here. In the graft, the right side of the middle hepatic vein or the left side of the left hepatic vein was cut longitudinally and a rectangular-shaped vein patch was attached for venoplasty. In the recipient, after the left and middle hepatic veins were joined, the right side of the middle hepatic vein was cut toward the closed right hepatic vein, making a horizontal cavotomy for anastomosis. Of 92 patients who underwent conventional hepatic vein reconstruction, 3 were complicated by hepatic venous stenosis (median follow-up 43 months). By contrast, there were no hepatic vein complications in the 20 patients who underwent the new technique (7 months). The current method appears to be technically feasible for outflow reconstruction in left liver graft transplantation. 相似文献
24.
J T Chen Y Kurokawa K Nakayama K Saito K Sakamoto K Fukuda Y Hirai T Hamada I Fujimoto K Yamauchi 《Nippon Sanka Fujinka Gakkai zasshi》1987,39(5):815-822
Bismuth subnitrate (BSN), a bismuth compound medically used for antidiarrheics, was orally administered to see whether it can reduce CDDP nephrotoxicity or not. Thirteen patients aged 19 approximately 60 with ovarian cancer entered this BSN-CDDP trial. A total of thirty three courses of BSN-CDDP treatment was undergone. BSN was administered orally at a dose of 50 mg/kg for five days before CDDP therapy. CDDP was infused for two hours. No vigorous hydration or diuresis was performed. Only 2,000 ml of saline with 20 mEq per liter of KCl was given for post-hydration. The median dose of CDDP was 100 mg/m2. The renal toxicity of BSN-CDDP treatment was minimum. 82% of the courses at the sixth day after the treatment had creatinine clearance levels which were more than 80% of those before the treatment. But twenty-four hour NAG and beta 2-microglobulin excretion were significantly increased. Bone marrow suppression and gastrointestinal disturbance were commonly observed. The results of our study indicate that BSN pretreatment reduces the renal toxicity of CDDP to some extent. 相似文献
25.
Serum lipid and apolipoprotein concentrations were measured in 37 male survivors of cerebral infarction (CI) and in 30 healthy controls. Both groups had similar total cholesterol levels, but the HDL-cholesterol level was significantly lower and the serum triglyceride level was significantly higher in the CI patients than in the controls. The ApoB level was significantly higher in the CI patients but there was no significant difference between the 2 groups in the levels of the other apolipoproteins (ApoA-I, A-II, C-II, C-III, and E). The HDL-cholesterol/ApoA-I ratio was significantly lower in the CI patients. Both the VLDL-triglyceride and VLDL-cholesterol levels were higher in the CI patients but the VLDL-cholesterol especially its cholesterol ester level was conspicuously high. A population of VLDL particles that bound to heparin on heparin-Sepharose columns was increased in the CI patients. We suggest that cholesterol ester is excessively transferred from HDL to VLDL during the disturbed catabolism of VLDL in CI patients. 相似文献
26.
H Watanabe Y Kamasaka T Higashihara T Inoue T Kuroda T Kozuka N Fujimoto Y Tada 《Clinical radiography》1989,34(12):1501-1504
We report two cases of unilateral renal angiomyolipoma. In both cases, our preoperative diagnosis was renal cell carcinoma because no low density area compatible with a fatty tissue was noted in the tumors. Histological examination revealed both tumors to be angiomyolipoma mainly composed of myomatous cells and immature fat cells. 相似文献
27.
28.
29.
Takuya Toyama Norihiko Ohura Masakazu Kurita Akira Momosawa Kiyonori Harii 《Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi》2006,40(6):329-334
We have investigated the effects of short-contact topical application of tretinoin using 16 male db/db mice by creating two full-thickness wounds on the skin of the back. A 0.1% tretinoin aqueous gel was applied to one wound for five minutes daily for five successive days while only aqueous gel was applied to the other (control). The mean (SD) percentage surface area unhealed before and after treatment were 0.88 (0.3) and 0.64 (0.15). In tretinoin-treated mice and non-treated mice (controls), the mean (SD) thicknesses of granulation were 1.383 (697) micro m and 683 (413) micro m, the density of capillary vessels in granulation was 12.2 (5.5)% and 5.7 (3.9)%, respectively. Differences between the two groups were significant for each variable. Wound healing was accelerated with short-contact topical application of tretinoin in db/db mice. 相似文献
30.
Resolution of homonymous visual field loss documented with functional magnetic resonance and diffusion tensor imaging. 总被引:5,自引:0,他引:5
Masaki Yoshida Masahiro Ida Thien Huong Nguyen Marie-Therese Iba-Zizen Luc Bellinger Jean Louis Stievenart Takehiko Nagao Shinsuke Kikuchi Takaaki Hara Takuya Shiba Kenji Kitahara Emmanuel Alain Cabanis 《Journal of neuro-ophthalmology》2006,26(1):11-17
A 68-year-old man developed right homonymous hemianopic paracentral scotomas from acute infarction of the left extrastriate area. He was studied over the ensuing 12 months with visual fields, conventional MRI, functional MRI (fMRI), and diffusion tensor imaging (DTI). As the visual field defect became smaller, fMRI demonstrated progressively larger areas of cortical activation. DTI initially showed that the lesioned posterior optic radiations were completely interrupted. This interruption lessened in time and had disappeared by one year after onset. fMRI and DTI are innovative measures to follow functional and structural recovery in the central nervous system. This is the first reported application of these imaging techniques to acute cerebral visual field disorders. 相似文献