全文获取类型
收费全文 | 5145篇 |
免费 | 299篇 |
国内免费 | 33篇 |
专业分类
耳鼻咽喉 | 24篇 |
儿科学 | 155篇 |
妇产科学 | 55篇 |
基础医学 | 708篇 |
口腔科学 | 125篇 |
临床医学 | 313篇 |
内科学 | 1260篇 |
皮肤病学 | 214篇 |
神经病学 | 389篇 |
特种医学 | 163篇 |
外科学 | 1121篇 |
综合类 | 11篇 |
预防医学 | 82篇 |
眼科学 | 79篇 |
药学 | 273篇 |
中国医学 | 6篇 |
肿瘤学 | 499篇 |
出版年
2023年 | 36篇 |
2022年 | 50篇 |
2021年 | 90篇 |
2020年 | 54篇 |
2019年 | 84篇 |
2018年 | 115篇 |
2017年 | 82篇 |
2016年 | 114篇 |
2015年 | 112篇 |
2014年 | 134篇 |
2013年 | 179篇 |
2012年 | 272篇 |
2011年 | 266篇 |
2010年 | 145篇 |
2009年 | 142篇 |
2008年 | 266篇 |
2007年 | 299篇 |
2006年 | 267篇 |
2005年 | 312篇 |
2004年 | 268篇 |
2003年 | 274篇 |
2002年 | 270篇 |
2001年 | 153篇 |
2000年 | 134篇 |
1999年 | 137篇 |
1998年 | 86篇 |
1997年 | 77篇 |
1996年 | 59篇 |
1995年 | 40篇 |
1994年 | 35篇 |
1993年 | 41篇 |
1992年 | 69篇 |
1991年 | 77篇 |
1990年 | 72篇 |
1989年 | 77篇 |
1988年 | 70篇 |
1987年 | 59篇 |
1986年 | 59篇 |
1985年 | 38篇 |
1984年 | 45篇 |
1983年 | 34篇 |
1982年 | 22篇 |
1981年 | 25篇 |
1979年 | 22篇 |
1978年 | 20篇 |
1977年 | 18篇 |
1973年 | 16篇 |
1971年 | 18篇 |
1970年 | 15篇 |
1968年 | 14篇 |
排序方式: 共有5477条查询结果,搜索用时 15 毫秒
21.
Steven G. E. Marsh Ekkehard D. Albert Walter F. Bodmer Ronald E. Bontrop Bo Dupont Henry A. Erlich Daniel E. Geraghty John A. Hansen Bernard Mach Wolfgang R. Mayr Peter Parham Effie W. Petersdorf Takehiko Sasazuki Geziena M. Th. Schreuder Jack L. Strominger Arne Svejgaard Paul I. Terasaki 《International journal of immunogenetics》2002,29(6):463-515
22.
23.
24.
25.
26.
27.
Antiinflammatory properties of the new antirheumatic agent 4-acetylaminophenylacetic acid 总被引:5,自引:0,他引:5
H Fujisawa T Nishimura Y Inoue S Ogaya Y Shibata Y Nakagawa S Sato K Kimura 《Arzneimittel-Forschung》1990,40(6):693-697
The antiinflammatory activity of 4-acetylaminophenylacetic acid (MS-932) was investigated. MS-932 did not suppress the acute inflammation of carrageenin-induced paw edema in rats or of primary swelling in adjuvant arthritic rats. However, prophylactic treatment with MS-932 inhibited secondary inflammation in adjuvant arthritic rats. MS-932 also restored to normal the weight of the spleen and the serum albumin/globulin ratio of adjuvant arthritic rats. In addition to its prophylactic effect, MS-932 had a therapeutic effect on adjuvant arthritis. In in vitro tests, MS-932 did not inhibit prostaglandin E2 biosynthesis from arachidonic acid by sheep seminal vesicle microsomal enzyme or superoxide generation by guinea pig neutrophils stimulated with opsonized zymosan. MS-932 had no analgesic effect in mice and no antipyretic effect in rats. These results indicate that MS-932 suppresses adjuvant arthritis through modulation of the immune system. 相似文献
28.
Shigetoshi Yoshida Yasuo Sekine Yukio Saitoh Kazuhiro Yasufuku Takekazu Iwata Takehiko Fujisawa 《Annals of thoracic and cardiovascular surgery》2005,11(1):7-11
BACKGROUND: Although rabbits have often been used as an experimental model for the analysis of lung preservation, there are no reports of long-term survival after rabbit lung allotransplantation. The purpose of this study was to establish a lung allotransplantation model for the evaluation of acute lung rejection in the rabbit and to investigate the transplantation techniques in the rabbit. METHODS: Left unilateral lung allotransplantations were performed in 10 pairs of Japanese white male rabbits, weighing from 2.8 to 3.7 kg. Rabbits were divided into two groups. Group A rabbits (n=5) received Cyclosporine A (CsA) (20 mg/kg/day) orally for 5 days postoperatively, while Group B rabbits (n=5) received no CsA. All rabbits were sacrificed at the fifth postoperative day for histological examinations. RESULTS: Anastomoses of the pulmonary vein were achieved by using the atrial cuff technique. Satisfied blood flow was obtained in all arterial and venous anastomosis sites. Bronchial anastomosis was also well healed and all rabbits could maintain adequate spontaneous ventilation. In Group A, histopathology revealed that three cases were grade A0, one was grade A1 and the other was A2. In Group B, three cases lived for five days, and histopathology showed two cases were grade A2 and one case was grade A3. CONCLUSION: We established a left unilateral lung allotransplantation model in the rabbit and observed suppression of acute rejection of the transplanted lung by CsA. This study suggests that the rabbit is also an experimental model suited for the analysis of lung preservation as well as lung allotransplant rejection. 相似文献
29.
Nobuyoshi Kawaharada Kiyofumi Morishita Johji Fukada Yoshikazu Hachiro Yasuaki Fujisawa Tatsuya Saito Yoshihiko Kurimoto Tomio Abe 《European journal of cardio-thoracic surgery》2005,27(4):622-625
OBJECTIVE: The risk of stroke caused by dislodgment of loose atheromatous plaque or mural emboli is increased by cross-clamping of the aorta. Some patients undergo descending thoracic aortic aneurysm repair with proximal aortic cross-clamping between the left common carotid artery and the left subclavian artery. The objective of this study was to determine the influence of proximal aortic cross-clamping in arteriosclerotic aneurysm or dissecting aneurysm repair. METHODS: Between May 1984 and May 2003, 81 patients underwent elective surgery for distal arch or descending aortic aneurysm repair with proximal aortic cross-clamping between the left common carotid artery and the left subclavian artery. To evaluate the influence of the proximal aortic cross-clamping, patients were divided into two groups: patients who had undergone arteriosclerotic aneurysm repair (group I, n=25) and patients who had undergone dissecting aneurysm repair (group II, n=56). RESULTS: Eight (9.9%) of the 81 patients had a stroke. Six strokes occurred in operations for arteriosclerotic aneurysm repair group I and two strokes occurred in operations for dissecting aneurysm repair group II (24 vs 3.6%; p=0.009). In-hospital mortality rates were 12% in group I and 8.9% in group II (p=0.70). Major postoperative complications included renal failure requiring hemodialysis (in 4.2% of the patients in group I and in 8.3% of the patients in group II, p=0.99) and pulmonary complication (in 20% of the patients in group I and in 16% of the patients in group II, p=0.67). CONCLUSION: Cross-clamping between head vessels should be avoided if at all possible when operating on patients who have arteriosclerotic descending thoracic aneurysms. 相似文献
30.
Takehiko Shimoyama Katsuo Yoshiya Yasushi Yamato Teruaki Koike Keiichi Honma 《General thoracic and cardiovascular surgery》2009,57(6):310-314
Malignant peripheral nerve sheath tumors (MPNSTs; malignant schwannomas) rarely occur in the anterior mediastinum, and their
prognosis is poor. A 75-year-old man was referred to our hospital for examination of an anterior mediastinal tumor. A computed
tomography-guided percutaneous needle biopsy revealed only fibrosis. The tumor was completely excised via a median sternotomy
with partial resection of the pericardium and right upper lobe of the lung. Thereafter, the tumor was diagnosed as a storiform-pleomorphic
type of malignant fibrous histiocytoma. At 1 year after the surgery, a distant metastasis was found in the interlobular space
between the right middle and lower lobes. The tumor was completely excised via a right posterolateral thoracotomy. Reexamination
of the primary and secondary tumors revealed an MPNST. No recurrence was found up to 5 years after the second surgery without
adjuvant chemotherapy or radiation therapy. However, he died from multiple lung metastases after 6 years. 相似文献