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991.
Suzuki HI Hangaishi A Hosoya N Watanabe T Kanda Y Motokura T Chiba S Kurokawa M 《International journal of hematology》2008,87(5):538-541
Neurological complications during the treatment of hematological malignancies have a wide range of causes. Treatment-related leukoencephalopathy has been recognized as a major complication of combined chemotherapy and radiotherapy for central nervous system (CNS) lymphoma, and can complicate the diagnosis of CNS infection. Herein, we present a patient with diffuse large B-cell lymphoma who developed herpes simplex encephalitis (HSE) and subsequent cytomegalovirus encephalitis after chemoradiotherapy for CNS relapse. Although cerebrospinal fluid examination (CSF) showed no significant pleocytosis, brain magnetic resonance imaging and polymerase chain reaction analysis of the CSF were useful in the diagnosis. With a review of the literature on the association between HSE and radiotherapy for CNS malignancies, our case suggests that an awareness of viral encephalitis is important in the differential diagnosis of acute neurologic disturbance during chemoradiotherapy for CNS lymphoma. 相似文献
992.
993.
Ozaki K Oda H Suzuki T Ohno Y Tsuchida K Takahashi K Miida T 《Journal of cardiology》2008,51(1):70-73
A 69-year-old woman underwent percutaneous coronary intervention for a severe stenotic lesion in the bifurcation of the mid-left anterior descending artery and first diagonal branch. A single stent was implanted into the left anterior descending artery. After the stent strut was dilated by balloon inflation in the diagonal branch, dissection occurred at the ostium of the diagonal branch and resulted in side branch occlusion due to hematoma. Bailout stenting was performed in the diagonal branch, but thrombus projection occurred in the left anterior descending artery. Aspiration, balloon inflation and thrombolytic therapy were performed, but distal embolism developed. This case illustrates that thrombus projection caused by stenting in a side branch may occur as a rare complication in percutaneous coronary intervention. 相似文献
994.
Kuriyama M Kato J Kuwaki K Morimoto N Nawa T Fujimoto T Kono H Okano N Miyaike J Morita T Okada H Suzuki S Yoshioka T Shiode J Suwaki K Sakaguchi K Shiratori Y;Japan West Ulcerative Colitis Study Group 《European journal of gastroenterology & hepatology》2008,20(7):634-641
BACKGROUND AND AIM: The health-related quality of life (HRQOL) of patients with ulcerative colitis (UC) can be impaired because of the chronic symptoms. Although UC patients suffer from such symptoms over the long term, there have been few reports on the changes of HRQOL with disease duration. The aim of this study was to clarify these changes. METHODS: The HRQOL of 331 Japanese UC patients was examined using the validated Japanese version of the Inflammatory Bowel Disease Questionnaire (J-IBDQ). HRQOL and factors affecting HRQOL identified using multiple linear regression analysis were stratified by disease duration. RESULTS: Of the 15 clinical factors examined, the clinical activity index score was the strongest determinant (P<0.0001) of all the scores of IBDQ regardless of disease duration. HRQOL did not differ significantly among patients with different disease durations. The factors, however, that affected HRQOL varied according to disease duration. In patients with disease duration of less than 5 years, the clinical activity index score was the predominant factor affecting HRQOL. Being 'on sick leave or hospitalized' was a significant factor impairing HRQOL in patients with disease duration of 5-9 years. Moreover, complications due to corticosteroids significantly impaired all of the IBDQ scores in patients with disease duration of 10 years or more. CONCLUSION: Factors that affected the HRQOL of UC patients varied according to the patients' disease duration. Our findings should assist in the development of a long-term strategy for the treatment of UC patients. 相似文献
995.
Okuzawa A Kobayashi S Sakamoto K Uchida Y Suzuki Y Ono K Seki E Tomiki Y Iwanuma Y Hayashida Y Kamano T Tsurumaru M 《Journal of gastroenterology》2000,35(9):717-720
Gastrinoma is a rare endocrine tumor that is frequently associated with liver metastasis. The liver metastasis is usually
seen simultaneously or soon after a primary operation. A 47-year-old woman who had had a total gastrectomy 20 years earlier
developed liver metastasis. An interval of this length between surgery and metastasis is extremely rare. The total gastrectomy
prevented the patient from developing the usual symptoms of hypergastrinemia that would have enabled early diagnosis of the
metastasis. Laboratory examinations on admission revealed a high serum gastrin concentration (1500 pg/ml). Computed tomography
showed an irregularly enhanced mass lesion with an uneven, low-density central area in the right anterior inferior segment
of the liver. An extended right hepatectomy was performed. Intraoperative ultrasonography showed no abnormalities in the remnant
pancreas. Examination of the cut surface of the specimen revealed a yellow, firm, elastic tumor, 55 mm in diameter. The interior
of the tumor appeared necrotic. Histopathologically, the tumor was composed of cells with hyperchromatic, dysplastic nuclei
arranged in a trabecular pattern with nest formation. Gastrin staining was positive. A histologic diagnosis of metastatic
gastrinoma was made. The patient's gastrin concentration returned to normal and she was well at 2-year follow-up.
Received: August 19, 1999 / Accepted: January 28, 2000 相似文献
996.
997.
998.
Erito Mochiki Hideki Suzuki Seiichi Takenoshita Yukio Nagamachi Hiroyuki Kuwano Akiyoshi Mizumoto Zen Itoh 《Journal of gastroenterology》1998,33(6):835-841
Glucagon is commonly used during gastrointestinal examinations for the temporary inhibition of gastroduodenal movements.
Three preparations of glucagon are now clinically available: those prepared by extraction from the pancreas (GL-P), by chemical
synthesis (GL-S), and by genetic recombination (GL-G). The aim of this study was examine the mechanism of the inhibitory effect
of glucagon on gastrointestinal motility and the cause of its side effects by comparing three glucagon preparations. In four
conscious dogs, gastrointestinal contractions were monitored by means of chronically implanted force transducers. Each glucagon
preparation (GL-P [15 μg/kg], GL-S [5, 15, 45 μg/kg], GL-G [15 μg/kg]), scopolamine butylbromide (0.4 mg/kg), or saline was
administered intravenously 20 min after the termination of spontaneous phase III contractions, and blood samples were taken
at 5- to 10-min intervals. Barium was administered into the stomach 10 min after the infusion of each drug. The arrival of
a barium meal in the stomach immediately stimulated gastrointestinal contractions, and the barium meal was expelled into the
duodenum and jejunum from the stomach. Intravenous injection of 15 μg GL-S first stimulated duodenal contractions that propagated
to the jejunum, followed by strong inhibition of the barium-induced gastrointestinal contractions. This inhibitory effect
of glucagon and the activity of the glucagon-induced duodenal contractions were dose-related. The inhibitory effects of GL-G
and GL-S were stronger than that of GL-P. Blood glucose and plasma insulin concentrations were raised after intravenous injection
of each glucagon preparation, but there was no difference among the three preparations and no dose relationship. The inhibitory
effects of glucagon depend on the material purity and dose, and the inhibitory mechanism was independent of any effect on
carbohydrate metabolism. Glucagon administration caused phase III-like contractions in the duodenum and jejunum, which may
be responsible for the side effects of glucagon.
(Received Jan. 8, 1998; accepted June 26, 1998) 相似文献
999.
A Yoshitomi H Kuwata T Suzuki M Masuda M Narushima S Imokawa K Tsukamoto T Suda K Chida H Nakamura 《Nihon Kokyūki Gakkai zasshi》2000,38(7):571-574
We report a rare case of tracheobronchomegaly with crescent-type tracheobronchomalacia. A 77-year-old man with a chronic cough was referred to our hospital because of fever and dyspnea. Radiographic examination showed enlargement of the trachea and main bronchi. On chest radiography, the transverse diameter of the trachea was 31 mm, and consolidation shadows were seen in both upper lung fields. Tracheobronchomegaly with pneumonia was diagnosed. The pneumonia was improved by administration of PAPM/BP. On bronchoscopic examination, the trachea and main bronchi were extremely dilated on inspiration, and were collapsed on expiration. The biopsy specimen from the bronchial mucosa showed non-specific chronic inflammation. 相似文献
1000.
Colorectal Stenting for Malignant and Benign Disease: Outcomes in Colorectal Stenting 总被引:15,自引:1,他引:15
Suzuki N Saunders BP Thomas-Gibson S Akle C Marshall M Halligan S 《Diseases of the colon and rectum》2004,47(7):1201-1207
INTRODUCTION: Self-expanding metal stents are now an established treatment for malignant colonic obstruction. Favorable outcomes have been reported both for cancer palliation and treatment of acute obstruction as a bridge to surgery. However, little data exists regarding the use of stents for benign colonic obstruction.METHODS: All cases of colonic stent insertion occurring between December 1996 to October 2002 were reviewed. During the study period, 36 patients with malignant obstruction and 6 patients with benign obstructive disease underwent placement of self-expandable stents using a combined endoscopic and fluoroscopic technique.RESULTS: Stent placement was successful in 36 of 42 patients (86 percent). Complications occurred in 16 of 36 patients (44 percent): migration (n = 7), reobstruction (n = 5), perforation (n = 2), fistula formation (n = 1), and stent fracture (n = 1). Stent placement was successful in 100 percent of patients with benign strictures but poststent migration was frequent (2/6).CONCLUSIONS: Stent insertion provided an effective outcome in patients with malignant colonic obstruction as a palliative and preoperative therapy. Although a relatively high migration rate was observed in patients with benign strictures, stenting was still effective in providing luminal patency (median follow-up, 7.5 months). Stenting should be considered as a first-line treatment for malignant strictures and as a potential therapy for selected benign strictures. 相似文献