全文获取类型
收费全文 | 16640篇 |
免费 | 1164篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 185篇 |
儿科学 | 689篇 |
妇产科学 | 414篇 |
基础医学 | 2067篇 |
口腔科学 | 215篇 |
临床医学 | 2303篇 |
内科学 | 3197篇 |
皮肤病学 | 238篇 |
神经病学 | 1508篇 |
特种医学 | 385篇 |
外科学 | 1482篇 |
综合类 | 266篇 |
一般理论 | 16篇 |
预防医学 | 2233篇 |
眼科学 | 186篇 |
药学 | 1094篇 |
中国医学 | 15篇 |
肿瘤学 | 1332篇 |
出版年
2023年 | 102篇 |
2022年 | 155篇 |
2021年 | 360篇 |
2020年 | 230篇 |
2019年 | 404篇 |
2018年 | 440篇 |
2017年 | 331篇 |
2016年 | 360篇 |
2015年 | 413篇 |
2014年 | 547篇 |
2013年 | 839篇 |
2012年 | 1257篇 |
2011年 | 1257篇 |
2010年 | 654篇 |
2009年 | 641篇 |
2008年 | 1029篇 |
2007年 | 1187篇 |
2006年 | 1123篇 |
2005年 | 1125篇 |
2004年 | 983篇 |
2003年 | 950篇 |
2002年 | 831篇 |
2001年 | 185篇 |
2000年 | 140篇 |
1999年 | 180篇 |
1998年 | 183篇 |
1997年 | 148篇 |
1996年 | 112篇 |
1995年 | 127篇 |
1994年 | 98篇 |
1993年 | 97篇 |
1992年 | 103篇 |
1991年 | 108篇 |
1990年 | 96篇 |
1989年 | 101篇 |
1988年 | 89篇 |
1987年 | 96篇 |
1986年 | 82篇 |
1985年 | 74篇 |
1984年 | 78篇 |
1983年 | 50篇 |
1982年 | 56篇 |
1981年 | 61篇 |
1980年 | 44篇 |
1979年 | 44篇 |
1978年 | 36篇 |
1977年 | 28篇 |
1976年 | 27篇 |
1975年 | 21篇 |
1974年 | 24篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
41.
Suzanne C. Tough David W. Johnston Jodi E. Siever Gayleen Jorgenson Linda Slocombe Carolyn Lane Margaret Clarke 《分娩》2006,33(3):183-194
ABSTRACT: Background: The addition of supplementary prenatal support may improve the health and well‐being of high‐risk women and families. The objective of this randomized controlled trial was to examine the impact of supplementary prenatal care on resource use among a community‐based population of pregnant women. Methods: Pregnant women from three urban maternity clinics were randomized (a) to current standard of physician care, (b) to current standard of care plus consultation with a nurse, or (c) to (b) plus consultation with a home visitor. Participants were 1,352 women who received 3 telephone interviews. The primary outcome was resource use (e.g., attended prenatal classes, used nutritional counseling). Results: Overall, those in the nurse intervention group were more likely to attend an “Early Bird” prenatal class and parenting classes, and to use nutrition counseling and agencies that assist with child care. Women provided with extra nursing and home visitation supports were more likely to use a written resource guide, nutrition counseling, and agencies that assist with child care. Among women at higher risk (e.g., language barriers, young maternal age, low income), the nurse intervention significantly increased use of early prenatal classes, whereas the nurse and home visitor intervention significantly increased use of the written resource guide and nutrition counseling. The intervention substantially increased the amount of information received on numerous pregnancy‐related topics but had little impact on resource use for mental health and poverty‐related needs. Among those with added support, resource use among low‐risk women was generally greater than among high‐risk women. Conclusions: Additional support provided by nurses, or nurses and home visitors, can successfully address informational needs and increase the likelihood that women will use existing community‐based resources. This finding was true even for high‐risk women, although this intervention did not reduce the difference in resource use between high‐ and low‐risk women. (BIRTH 33:3 September 2006) 相似文献
42.
Huntington's disease (HD) is a neurodegenerative disorder associated with expansion of CAG trinucleotide repeats in the huntingtin gene. A minimum of 36 CAG repeats is usually reported in patients with clinical features of HD; 30 to 35 repeats represent an intermediate range. Here we report a 65-year-old male with autopsy-proven HD and 29 CAG repeats. 相似文献
43.
Lorraine N Clark Eneli Haamer Helen Mejia-Santana Juliette Harris Suzanne Lesage Alexandra Durr Sabine Janin Bs Katja Hedrich Elan D Louis Lucien J Cote Howard Andrews Stanley Fahn Cheryl Waters Blair Ford Steven Frucht William Scott Christine Klein Alexis Brice Hanno Roomere Ruth Ottman Karen Marder 《Movement disorders》2007,22(7):932-937
Parkin mutations account for the majority of familial and sporadic early onset Parkinson's disease (EOPD) cases with a known genetic association. More than 100 mutations have been described in the Parkin gene that includes homozygous, compound heterozygous, and single heterozygous mutations. We have designed a Parkin mutation genotyping array (gene chip) that includes published Parkin sequence variants and allows their simultaneous detection. The chip was validated by screening 85 PD cases and 47 controls previously tested for Parkin mutations. Similar genotyping microarrays have been developed for other genetically heterogeneous diseases including age-related macular degeneration. Here, we show the utility of a genotyping array for Parkinson's disease by analysis of 60 subjects from the Genetic Epidemiology of Parkinson Disease (GEPD) study that includes 15 early-onset PD case probands and 45 relatives. 相似文献
44.
Suzanne Christopher Tim Dunnagan George Haynes Lili Stiff 《Behavioral and brain functions : BBF》2007,3(1):10-9
Background
A multi-state consortium was developed in the US to conduct baseline data collection and intervention research on fetal alcohol syndrome. Each state employed support specialists whose job it was to reduce or eliminate alcohol consumption in women who were at high risk for drinking alcohol during their pregnancy. The purpose of this paper is to report how support specialists in three primarily rural/frontier states were trained to assess client need and how client need was actually assessed in the field. 相似文献45.
46.
Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort. 总被引:8,自引:0,他引:8
Dora Il'yasova Lisa H Colbert Tamara B Harris Anne B Newman Douglas C Bauer Suzanne Satterfield Stephen B Kritchevsky 《Cancer epidemiology, biomarkers & prevention》2005,14(10):2413-2418
BACKGROUND: Chronic inflammation is associated with processes that contribute to the onset or progression of cancer. This study examined the relationships between circulating levels of the inflammatory markers interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-alpha) and total as well as site-specific cancer incidence. METHODS: Study subjects (n = 2,438) were older adults (ages 70-79 years) participating in the Health Aging and Body Composition study, who did not report a previous cancer diagnosis (except for nonmelanoma skin cancer) at baseline. Incident cancer events (n = 296) were ascertained during an average follow-up of 5.5 years. Inflammatory markers were measured in stored baseline fasting blood samples. RESULTS: The adjusted hazard ratios (95% confidence intervals) for incident cancer associated with a 1-unit increase on the natural log-scale were 1.13 (0.94-1.37), 1.25 (1.09-1.43), and 1.28 (0.96-1.70) for IL-6, CRP, and TNF-alpha, respectively. Markers were more strongly associated with cancer death: hazard ratios were 1.63 (1.19-2.23) for IL-6, 1.64 (1.20-2.24) for CRP, and 1.82 (1.14-2.92) for TNF-alpha. Although precision was low for site-specific analyses, our results suggest that all three markers were associated with lung cancer, that IL-6 and CRP were associated with colorectal cancer, and that CRP was associated with breast cancer. Prostate cancer was not associated with any of these markers. CONCLUSIONS: These findings suggest that (a) the associations between IL-6, CRP, and TNF-alpha and the risk of cancer may be site specific and (b) increased levels of inflammatory markers are more strongly associated with the risk of cancer death than cancer incidence. 相似文献
47.
48.
Thompson Debra A.; Janecke Andreas R.; Lange Jessica; Feathers Kecia L.; Hubner Christian A.; McHenry Christina L.; Stockton David W.; Rammesmayer Gabriele; Lupski James R.; Antinolo Guillermo; Ayuso Carmen; Baiget Montserrat; Gouras Peter; Heckenlively John R.; den Hollander Anneke; Jacobson Samuel G.; Lewis Richard A.; Sieving Paul A.; Wissinger Bernd; Yzer Suzanne; Zrenner Eberhart; Utermann Gerd; Gal Andreas 《Human molecular genetics》2006,15(9):1559
Human Molecular Genetics 相似文献
49.
Lynn McIntyre Edwin G. Belzer Lise Manchester Wade Blanchard Suzanne Officer A. Catherine Simpson 《The Journal of school health》1996,66(3):132-137
ABSTRACT: The Dartmouth Health Promotion Study was a longitudinal, quasi-experimental field study with a qualitative research arm, designed to learn whether coordinating school health instruction, health services, and a healthful environment enhanced the program's effect on the heart health and mental health of children. The research strategy — the Coordinated Approach — was applied to approximately 300 children in each of two cohorts in grades four to six attending nine trial schools; a further 600 children attended 10 comparison schools in Dartmouth and nine distal comparison schools. Although the qualitative analysis demonstrated that positive feelings were engendered in most areas of the study, when either the classroom or the individual was used as the unit of analysis, the Coordinated Approach did not have a more favorable effect on the heart or mental health of children than did the standard school health program. Thus, the effect of an existing school health program was not directly enhanced through coordinating its components. 相似文献
50.