放置不锈钢宫内节育器20年的子宫内膜亚显微结构的变化

为了了解放置不锈钢宫内节育器的安全性,我们收集了8例放置不锈钢宫内节育器20年、月经正常妇女之子宫内膜,在亚显微水平观察其变化。结果指出:压迫区子宫内膜有不同程度之萎缩或变性;移行区子宫内膜有轻度变性、轻度增生、个别细胞肥大及鳞状化生,未见明显癌变;远离区则无明显病变,对内源性性激素反应比较正常,即使核内管道系统与巨大线粒体亦仍在第17、19天两侧内膜中出现。因此,认为放置不锈钢宫内节育器20年后之子宫内膜不一定会发生严重的破坏或癌变。结合临床分析,将不锈钢宫内节育器存放时间延长至20年是可以的。     

Forty-years (1961-2001) of all-cause and coronary heart disease mortality and its determinants: the Corfu cohort from the Seven Countries Study

AIMS: This study examined risk factors in relation to 40-year all-cause and coronary heart disease mortality in the Corfu cohort of the Seven Countries Study. METHODS: The population studied in this analysis consisted of 529 rural middle-aged men enrolled in 1961. Multivariate analysis was performed using the proportional hazards Cox model with all-cause as well as coronary heart disease death as end points and age, blood pressure, serum total cholesterol, smoking, physical activity, body mass index, skinfold thickness, vital capacity and forced expiratory volume as predictors. RESULTS: The 40-year all-cause mortality rate was 87.1% (461 deaths/529 individuals at entry), while the CHD mortality rate was 22.7% (120 deaths/529 individuals at entry). The proportion of CHD deaths varied from 16 to 28.5% of all deaths during the period investigated. Age (hazard ratio (HR)=1.08, P<0.001), smoking (HR=1.40, P<0.01), diastolic blood pressure (HR=1.01, P<0.05), and forced expiratory volume (HR=0.97, P<0.05) were independently associated with 40-year all-cause mortality. Moreover, age (HR=1.093, P<0.001), smoking (HR=1.596, P<0.05), and body mass index (HR=1.05, P<0.05) were independently associated with 40-year CHD mortality. CONCLUSION: Among the investigated cardiovascular risk factors, age, smoking, physical activity, skinfold thickness, diastolic blood pressure, and forced expiratory volume seem to be associated with all-cause mortality, while age, smoking, and body mass index were consistently associated with 40-year CHD mortality.     

家庭教育在社区精神分裂症患者社会功能康复中作用的探讨

为探讨家庭教育对精神分裂症患者社会功能康复的有效性和可行性，对济南市区125例精神分裂症患者亲属（主要照料者）进行了为期一年的家庭教育前瞻性对照研究，结果显示：教育组社会功能的康复较教育前有非常显著的提高，与对照组相比差异有统计学意义，提示家庭教育能够改善患者的社会功能，有利于患者的社会康复．     

异常Ptfv_1对肺心病合并冠心病的诊断价值

为探讨异常Ptfv1对肺心病合并冠心病诊断价值，检查100例非心脏病者，98例肺心病患者，62例肺心病合并冠心病患者12个心电图常规导联，测定其Ptfv1值，并于治疗前后复查．结果：正常人组Ptfv1均＞-003mm·s．Ptfv1阳性率肺心组为58．3％，肺冠组为61．2％（P＞0．05）．两组病人治疗前后阳性率均显著下降．左房扩大和（或）左室扩大者Ptfv1阳性率高．结论：肺心病患者Ptfv1阳性率不低，且受较多因素影响，对肺心病合并冠心病诊断价值不大，与心脏功能密切相关，值得注意．     

抽动──秽语综合征139例临床资料分析

报告139例抽动──秽语综合征的临床资料，认为本病的诊断主要依靠典型的抽动发作，即使不伴有异常发声或秽语，在排除类似疾病后也可确诊．氟哌啶醇与等量安坦合用并从小剂量开始给药的治疗方法安全而有效，有效率达94％，但应注意减停药物过早易致症状复发。提出本病可能与遗传、精神刺激及脑器质性损害有关。