全文获取类型
收费全文 | 71749篇 |
免费 | 4846篇 |
国内免费 | 201篇 |
专业分类
耳鼻咽喉 | 529篇 |
儿科学 | 2091篇 |
妇产科学 | 1166篇 |
基础医学 | 9832篇 |
口腔科学 | 1505篇 |
临床医学 | 7523篇 |
内科学 | 15209篇 |
皮肤病学 | 981篇 |
神经病学 | 6823篇 |
特种医学 | 2227篇 |
外国民族医学 | 1篇 |
外科学 | 10043篇 |
综合类 | 878篇 |
一般理论 | 72篇 |
预防医学 | 6392篇 |
眼科学 | 1737篇 |
药学 | 4906篇 |
1篇 | |
中国医学 | 80篇 |
肿瘤学 | 4800篇 |
出版年
2023年 | 376篇 |
2022年 | 521篇 |
2021年 | 1397篇 |
2020年 | 839篇 |
2019年 | 1364篇 |
2018年 | 1659篇 |
2017年 | 1237篇 |
2016年 | 1356篇 |
2015年 | 1582篇 |
2014年 | 2366篇 |
2013年 | 3210篇 |
2012年 | 5236篇 |
2011年 | 5367篇 |
2010年 | 3001篇 |
2009年 | 2666篇 |
2008年 | 4873篇 |
2007年 | 5332篇 |
2006年 | 5237篇 |
2005年 | 4969篇 |
2004年 | 4765篇 |
2003年 | 4309篇 |
2002年 | 4204篇 |
2001年 | 573篇 |
2000年 | 403篇 |
1999年 | 634篇 |
1998年 | 899篇 |
1997年 | 754篇 |
1996年 | 634篇 |
1995年 | 605篇 |
1994年 | 490篇 |
1993年 | 464篇 |
1992年 | 347篇 |
1991年 | 304篇 |
1990年 | 256篇 |
1989年 | 246篇 |
1988年 | 261篇 |
1987年 | 213篇 |
1986年 | 231篇 |
1985年 | 240篇 |
1984年 | 308篇 |
1983年 | 324篇 |
1982年 | 384篇 |
1981年 | 369篇 |
1980年 | 343篇 |
1979年 | 197篇 |
1978年 | 239篇 |
1977年 | 191篇 |
1976年 | 133篇 |
1975年 | 102篇 |
1974年 | 105篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
992.
993.
ABSTRACT Background: Motor deficits after stroke are a primary cause of long-term disability. The extent of functional recovery may be influenced by genetic polymorphisms. Objectives: Determine the effect of genetic polymorphisms for brain-derived neurotrophic factor (BDNF), catechol-O-methyltransferase (COMT), and apolipoprotein E (APOE) on walking speed, walking symmetry, and ankle motor control in individuals with chronic stroke. Methods: 38 participants with chronic stroke were compared based upon genetic polymorphisms for BDNF (presence [MET group] or absence [VAL group] of a Met allele), COMT (presence [MET group] or absence [VAL group] of a Met allele), and APOE (presence [ε4+ group] of absence [ε4- group] of ε4 allele). Comfortable and maximal walking speed were measured with the 10-m walk test. Gait spatiotemporal symmetry was measured with the GAITRite electronic mat; symmetry ratios were calculated for step length, step time, swing time, and stance time. Ankle motor control was measured as the accuracy of performing an ankle tracking task. Results: No significant differences were detected (p ≥ 0.11) between the BDNF, COMT, or APOE groups for any variables. Conclusions: In these preliminary findings, genetic polymorphisms for BDNF, COMT, and APOE do not appear to affect walking speed, walking symmetry, or ankle motor performance in chronic stroke. 相似文献
994.
995.
Chromosomal instability (CIN) is a hallmark of cancer and has been implicated in cancer initiation, progression and the development of resistance to traditional cancer therapy. Here we identify a new property of CIN cells, showing that inducing CIN in proliferating Drosophila larval tissue leads to the activation of innate immune signalling in CIN cells. Manipulation of this immune pathway strongly affects the survival of CIN cells, primarily via JNK, which responds to both Toll and TNFα/Eiger. This pathway also activates Mmp1, which recruits hemocytes to the CIN tissue to provide local amplification of the immune response that is needed for effective elimination of CIN cells. 相似文献
996.
997.
998.
Peter Andrew Yasir Hamad Sandra Jerat Annibale Montenero Stephen O’Connor 《Journal of interventional cardiac electrophysiology》2011,32(1):17-27
Purpose
Despite increasingly widespread use of cryo catheter ablation (CCA) in clinical practice, current ACC/AHA/ESC guidelines for management of supraventricular arrhythmias cite only radiofrequency catheter ablation (RFCA) as first-line treatment for type 1 atrial flutter (AFL). We performed a meta-analysis of efficacy and procedure outcomes from randomized controlled clinical trials comparing CCA with RFCA for type 1 AFL. A systematic review of non-randomized, single-arm clinical studies of CCA for type 1 AFL was also done. 相似文献999.
Claire Dendle Michael Gilbertson Tony M. Korman Vera Golder Eric Morand Stephen Opat 《Emerging infectious diseases》2015,21(9):1661-1663
Two cases of disseminated enteroviral infection occurred in patients who received the CD20 monoclonal antibody obinutuzumab. Clinical features included hepatitis, edema, and a dermatomyositis-like syndrome. These manifestations may be unfamiliar to clinicians and are possibly responsive to intravenous immunoglobulin. Clinicians should remain vigilant for enteroviral infections in patients receiving obinutuzumab. 相似文献
1000.
Angela Sun Quynh Bui Janice Y. Tsoh Ginny Gildengorin Joanne Chan Joyce Cheng Ky Lai Stephen McPhee Tung Nguyen 《Journal of immigrant and minority health / Center for Minority Public Health》2017,19(2):381-391
Having an Advance Directive (AD) can help to guide medical decision-making. Asian Americans (AA) are less likely than White Americans to complete an AD. This pilot study investigated the feasibility and efficacy of a church-based intervention to increase knowledge and behavior change related to AD among Chinese and Vietnamese Americans. This study utilized a single group pre- and post-intervention design with 174 participants from 4 churches. Domain assessed: demographics; AD-related knowledge, beliefs, attitudes, and intentions; AD completion; and conversations with a healthcare proxy. Data were analyzed using Chi square and multiple logistic regression techniques. We observed significant increases in participants’ AD-related knowledge, intentions, and a gain in supportive beliefs and attitudes about AD, resulting in 71.8 % AD completion, and 25.0 % having had a proxy conversation. Providing culturally-tailored intervention and step-by-step guidance can help to achieve significant changes in AD related knowledge and behavior in AA church goers. 相似文献