全文获取类型
收费全文 | 82997篇 |
免费 | 8310篇 |
国内免费 | 164篇 |
专业分类
耳鼻咽喉 | 1181篇 |
儿科学 | 2522篇 |
妇产科学 | 1795篇 |
基础医学 | 11871篇 |
口腔科学 | 2006篇 |
临床医学 | 10182篇 |
内科学 | 14703篇 |
皮肤病学 | 1304篇 |
神经病学 | 6731篇 |
特种医学 | 2883篇 |
外国民族医学 | 10篇 |
外科学 | 11416篇 |
综合类 | 1669篇 |
一般理论 | 67篇 |
预防医学 | 9480篇 |
眼科学 | 1852篇 |
药学 | 6764篇 |
2篇 | |
中国医学 | 83篇 |
肿瘤学 | 4950篇 |
出版年
2021年 | 1115篇 |
2020年 | 738篇 |
2019年 | 1119篇 |
2018年 | 1395篇 |
2017年 | 1005篇 |
2016年 | 1093篇 |
2015年 | 1242篇 |
2014年 | 1639篇 |
2013年 | 2573篇 |
2012年 | 3472篇 |
2011年 | 3745篇 |
2010年 | 2003篇 |
2009年 | 1924篇 |
2008年 | 3235篇 |
2007年 | 3551篇 |
2006年 | 3420篇 |
2005年 | 3476篇 |
2004年 | 3249篇 |
2003年 | 3026篇 |
2002年 | 2956篇 |
2001年 | 2724篇 |
2000年 | 2830篇 |
1999年 | 2507篇 |
1998年 | 1089篇 |
1997年 | 897篇 |
1996年 | 898篇 |
1995年 | 810篇 |
1994年 | 836篇 |
1993年 | 750篇 |
1992年 | 2094篇 |
1991年 | 2028篇 |
1990年 | 1897篇 |
1989年 | 1873篇 |
1988年 | 1785篇 |
1987年 | 1789篇 |
1986年 | 1691篇 |
1985年 | 1674篇 |
1984年 | 1393篇 |
1983年 | 1261篇 |
1982年 | 842篇 |
1981年 | 720篇 |
1980年 | 642篇 |
1979年 | 1214篇 |
1978年 | 874篇 |
1977年 | 766篇 |
1976年 | 719篇 |
1975年 | 717篇 |
1974年 | 859篇 |
1973年 | 754篇 |
1972年 | 733篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
12.
Yasmine Yousef Etienne St-Louis Robert Baird Emily R. Smith Elena Guadagno Dickens St-Vil Dan Poenaru 《Journal of pediatric surgery》2019,54(4):831-837
Background
The Lancet Commission on Global Surgery highlighted global surgical need but offered little insight into the specific surgical challenges of children in low-resource settings. Efforts to strengthen the quality of global pediatric surgical care have resulted in a proliferation of partnerships between low-and middle-income countries (LMICs) and high-income countries (HICs). Standardized tools able to reliably measure gaps in delivery and quality of care are important aids for these partnerships. We undertook a systematic review (SR) of capacity assessment tools (CATs) focused on needs assessment in pediatric surgery.Methods
A comprehensive search strategy of multiple electronic databases was conducted per PRISMA guidelines without linguistic or temporal restrictions. CATs were selected according to pre-defined inclusion criteria. Articles were assessed by two independent reviewers. Methodological quality of studies was appraised using the COSMIN checklist with 4-point scale.Results
The search strategy generated 16,641 original publications, of which three CATs were deemed eligible. Eligible tools were either excessively detailed or oversimplified. None used weighted scores to identify finer granularity between institutions. No CATs comprehensively included measures of resources, outcomes, accessibility/impact and training.Discussion
The results of this study identify the need for a CAT capable of objectively measuring key aspects of surgical capacity and performance in a weighted tool designed for pediatric surgical centers in LMICs.Type of Study
Systematic Review.Level of Evidence
II. 相似文献13.
Joseph Wheatley Zhengyang Liu Joel Loth Mark P. Plummer Jahan C. Penny-Dimri Reny Segal Julian Smith Luke A. Perry 《Acta anaesthesiologica Scandinavica》2023,67(2):131-141
Background
Patients undergoing cardiac surgery are at significant risk of developing postoperative acute kidney injury (AKI). Neutrophil–lymphocyte ratio (NLR) is a widely available inflammatory biomarker which may be of prognostic value in this setting.Methods
We conducted a systematic review and meta-analysis of studies reporting associations between perioperative NLR with postoperative AKI. We searched Medline, Embase and the Cochrane Library, without language restriction, from inception to May 2022 for relevant studies. We meta-analysed the reported odds ratios (ORs) with 95% confidence intervals (CIs) for both elevated preoperative and postoperative NLR with risk of postoperative AKI and need for renal replacement therapy (RRT). We conducted a meta-regression to explore inter-study statistical heterogeneity.Results
Twelve studies involving 10,724 participants undergoing cardiac surgery were included, with eight studies being deemed at high risk of bias using PROBAST modelling. We found statistically significant associations between elevated preoperative NLR and postoperative AKI (OR 1.45, 95% CI 1.18–1.77), as well as postoperative need for RRT (OR 2.37, 95% CI 1.50–3.72). Postoperative NLR measurements were not of prognostic significance.Conclusions
Elevated preoperative NLR is a reliable inflammatory biomarker for predicting AKI following cardiac surgery. 相似文献14.
Nicola Flaum Emma J. Crosbie Richard J. Edmondson Miriam J. Smith Dafydd G. Evans 《Clinical genetics》2020,97(1):54-63
Ovarian cancer is the fourth most common cause of cancer-related death in women in the developed world, and one of the most heritable cancers. One of the most significant risk factors for epithelial ovarian cancer (EOC) is a family history of breast and/or ovarian cancer. Combined risk factors can be used in models to stratify risk of EOC, and aid in decisions regarding risk-reduction strategies. Germline pathogenic variants in EOC susceptibility genes including those involved in homologous recombination and mismatch repair pathways are present in approximately 22% to 25% of EOC. These genes are associated with an estimated lifetime risk of EOC of 13% to 60% for BRCA1 variants and 10% to 25% for BRCA2 variants, with lower risks associated with remaining genes. Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) thought to explain an additional 6.4% of the familial risk of ovarian cancer, with 34 susceptibility loci identified to date. However, an unknown proportion of the genetic component of EOC risk remains unexplained. This review comprises an overview of individual genes and SNPs suspected to contribute to risk of EOC, and discusses use of a polygenic risk score to predict individual cancer risk more accurately. 相似文献
15.
Evaluation of training nurses to perform semi‐automated three‐dimensional left ventricular ejection fraction using a customised workstation‐based training protocol 下载免费PDF全文
16.
17.
18.
James I. Geller MD Joseph G. Pressey MD Malcolm A. Smith MD Rachel A. Kudgus PhD Mariana Cajaiba MD Joel M. Reid PhD David Hall PhD Donald A. Barkauskas PhD Stephen D. Voss MD Steve Y. Cho MD Stacey L. Berg MD Jeffrey S. Dome MD PhD Elizabeth Fox MD Brenda J. Weigel MD 《Cancer》2020,126(24):5303-5310
19.
Béla Nagy Zsolt Bene Zsolt Fejes Sonya L. Heltshe David Reid Nicola J. Ronan Yvonne McCarthy Daniel Smith Attila Nagy Elizabeth Joseloff György Balla János Kappelmayer Milan Macek Scott C. Bell Barry J. Plant Margarida D. Amaral István Balogh 《Journal of cystic fibrosis》2019,18(2):271-277