全文获取类型
收费全文 | 2710篇 |
免费 | 92篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 13篇 |
妇产科学 | 18篇 |
基础医学 | 261篇 |
口腔科学 | 114篇 |
临床医学 | 166篇 |
内科学 | 760篇 |
皮肤病学 | 16篇 |
神经病学 | 164篇 |
特种医学 | 113篇 |
外科学 | 393篇 |
综合类 | 11篇 |
预防医学 | 151篇 |
眼科学 | 18篇 |
药学 | 210篇 |
中国医学 | 7篇 |
肿瘤学 | 395篇 |
出版年
2023年 | 12篇 |
2022年 | 29篇 |
2021年 | 65篇 |
2020年 | 25篇 |
2019年 | 40篇 |
2018年 | 59篇 |
2017年 | 57篇 |
2016年 | 54篇 |
2015年 | 63篇 |
2014年 | 84篇 |
2013年 | 86篇 |
2012年 | 167篇 |
2011年 | 166篇 |
2010年 | 118篇 |
2009年 | 98篇 |
2008年 | 194篇 |
2007年 | 207篇 |
2006年 | 207篇 |
2005年 | 196篇 |
2004年 | 191篇 |
2003年 | 160篇 |
2002年 | 139篇 |
2001年 | 35篇 |
2000年 | 28篇 |
1999年 | 33篇 |
1998年 | 44篇 |
1997年 | 33篇 |
1996年 | 34篇 |
1995年 | 30篇 |
1994年 | 15篇 |
1993年 | 20篇 |
1992年 | 20篇 |
1991年 | 15篇 |
1990年 | 15篇 |
1989年 | 8篇 |
1988年 | 14篇 |
1987年 | 5篇 |
1986年 | 4篇 |
1985年 | 3篇 |
1984年 | 8篇 |
1983年 | 3篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1980年 | 5篇 |
1979年 | 5篇 |
1978年 | 6篇 |
1975年 | 3篇 |
1973年 | 3篇 |
1972年 | 2篇 |
1929年 | 2篇 |
排序方式: 共有2818条查询结果,搜索用时 15 毫秒
51.
Yasunori Tojo Shuji Bandoh Jiro Fujita Tomoya Ishii Yutaka Ueda Taku Okamoto Cheng-Long Hwang Hiroyasu Yokomise Masashi Ishikawa Shoji Kobayashi Toshihiko Ishida 《Nihon Kokyūki Gakkai zasshi》2003,41(7):474-479
We present a case of a synchronous primary lung cancer adjacent to a hamartoma. In a 48-year-old man, a nodular shadow was found in the right middle lung field in 1990, and had grown slowly for 10 years. Another mass shadow was detected in the right upper lung field in 2000. The patient was admitted to our hospital for further examination of these abnormal shadows. Bronchoscopic examination revealed, in the right upper lobe, a poorly differentiated adenocarcinoma of clinical stage IIIB. Neoadjuvant chemotherapy followed by pneumonectomy was performed. The microscopic findings for the tumor resected from the right S2 showed poorly differentiated adenocarcinoma and those for the other, in the right S3, showed chondromatous hamartoma. Some 50 reports of lung cancer in parents with a chondromatous hamartoma have appeared in the literature. Most of these cases have some common features as follows: 1) men past middle age, 2) adenocarcinoma, and 3) lung cancer and chondromatous hamartoma present in the same lobe. The present case had all of these features, and may assist in the understanding of the process of development of lung cancer adjacent to a hamartoma. 相似文献
52.
Shinji Kitamura Hiroyasu Iishi Masaharu Tatsuta Hideki Ishikawa Tomohiko Hiyama Hideaki Tsukuma Hiroshi Kasugai Sachiko Tanaka Tsugio Kitamura Shingo Ishiguro 《Gastroenterology》1995,108(6):1778-1784
Ultrasonography should be used for screening of hepatocellular carcinoma, but there are few reports on the relationship between liver ultrasonographic findings and the development of hepatocellular carcinoma (HCC). Using prospective follow-up studies, we examined the role of liver with a hypoechoic nodular pattern as a high-risk factor in HCC. The study was performed by follow-up on 593 patients with chronic liver disease recorded at our hospital. The ultrasonographic pattern of the liver parenchyma was classified either as a small or large hypoechoic nodular pattern or as a nonnodular pattern. Patients were followed up from the time of initial ultrasonographic examination (1985–1987) until January 1, 1991. During the follow-up period (average, 4.2 years, range, 0.3–6.0 years), 62 patients were found to have HCC (12%). Patients whose livers showed small or large hypoechoic nodular pattern had a significantly higher risk of HCC than did patients whose livers showed a nonnodular pattern (rate ratios were 14.0 and 20.0, respectively, adjusted for age, sex, hepatitis virus markers, ICG R15, α-fetoprotein concentration, and ultrasonographic pattern of the liver). Liver showing a hypoechoic nodular pattern is a major risk factor in HCC. 相似文献
53.
Video‐assisted thoracoscopic surgery can help enable the complete resection of a mediastinal tumor caused by immunoglobulin G4‐related disease and avoid the need for postoperative medication: A case report
下载免费PDF全文
![点击此处可从《Asian journal of endoscopic surgery》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Tsuyoshi Uchida Hirochika Matsubara Satoshi Nagasaka Satsuki Kina Tomofumi Ichihara Hiroyasu Matsuoka Hiroyuki Nakajima 《Asian journal of endoscopic surgery》2018,11(3):248-251
Immunoglobulin (Ig) G4‐related disease has various clinical signs and symptoms, and steroidal therapy with corticosteroids has been found to be effective for treatment. Few cases of IgG4‐related disease associated with paravertebral tumor have been reported, and there have been no reports on complete resection of such a tumor. Here, we report a case of IgG4‐related disease associated with a paravertebral tumor that was successfully resected without the need for postoperative medication. An 84‐year‐old woman was admitted to our hospital with a paravertebral tumor. She underwent thoracoscopic surgery, and pathological examination of the tumor specimen revealed that the tumor resulted from IgG4‐related disease. After resection, there was no need for postoperative medication. Our case indicates the rare possibility of a paravertebral tumor associated with IgG4‐related disease and the potential for complete resection as a treatment for such a tumor. 相似文献
54.
Chaochen Wang Hiroshi Yatsuya Koji Tamakoshi Hiroyasu Iso Akiko Tamakoshi 《Journal of epidemiology / Japan Epidemiological Association》2015,25(1):66-73
Background
Findings regarding the association between milk consumption and all-cause mortality reported by studies carried out in Western populations have been inconsistent. However, no studies have been conducted in Japan on this issue. The present study aimed to investigate the association of milk drinking with all-cause, cardiovascular, and cancer mortality in Japan.Methods
The data were obtained from the Japan Collaborative Cohort (JACC) study. A total of 94 980 Japanese adults aged 40–79 years who had no history of cancer, stroke, or chronic cardiovascular diseases were followed between 1988 and 2009. Multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of mortalities were assessed using a Cox proportional hazard regression model and taking the lowest milk consumption group as the reference.Results
During a median of 19 years of follow-up, there were 21 775 deaths (28.8% and 35.3% from cardiovascular diseases and cancer, respectively). Drinking milk 1–2 times a month was associated with lower all-cause mortality in men compared to those who never drank milk (multivariable-adjusted HR 0.92; 95% CI, 0.85–0.99). In women, those who drank 3–4 times a week also had a lower mortality risk compared with those who never drank milk (HR 0.91; 95% CI 0.85–0.98). Inverse associations between drinking milk and mortality from cardiovascular diseases and cancer were found only in men.Conclusions
Drinking milk at least 1–2 times a month was associated with lower all-cause mortality in men compared to never drinking milk. An inverse association was also found between drinking milk and mortality from both cardiovascular diseases and cancer. However, lower all-cause mortality in women was found only in those who drank milk 3–4 times/week.Key words: milk drinking, all-cause mortality, prospective study 相似文献55.
Shigekazu Ukawa Akiko Tamakoshi Hiroshi Yatsuya Kazumasa Yamagishi Masahiko Ando Hiroyasu Iso 《Journal of epidemiology / Japan Epidemiological Association》2015,25(6):431-436
Background
Sedentary behavior is associated with cardiovascular disease, diabetes mellitus, and cancer morbidity, and watching television (TV) is an important sedentary behavior. The aim of this study is to clarify the association between TV viewing time and chronic obstructive pulmonary disease (COPD)-related mortality in Japanese adults.Methods
Using the Cox proportional hazard model, we assessed COPD-related mortality by TV viewing time in a national cohort of 33 414 men and 43 274 women without cancer, stroke, myocardial infarction, or tuberculosis at baseline (1988–1990).Results
The median follow-up was 19.4 years; 244 men and 34 women died of COPD. Men watching ≥4 hours/day of TV were more likely to die of COPD than those watching <2 hours/day (hazard ratio 1.63; 95% confidence interval, 1.04–2.55), independent of major confounders. No association was found in women.Conclusions
Avoiding a sedentary lifestyle, particularly prolonged TV viewing, may help in preventing death from COPD among men.Key words: chronic obstructive pulmonary disease, sedentary behavior, obstructive lung disease, cohort study, risk assessment 相似文献56.
Hino Hitoshi Shiomi Akio Hatakeyama Keiichi Kagawa Hiroyasu Manabe Shoichi Yamaoka Yusuke Nagashima Takeshi Ohshima Keiichi Urakami Kenichi Akiyama Yasuto Yamaguchi Ken 《Journal of gastroenterology》2022,57(7):476-485
Journal of Gastroenterology - In clinical practice, rectal cancer (RC) is classified according to tumor location. However, RC’s genetic characteristics according to tumor location remain... 相似文献
57.
58.
Cui R Moriyama Y Koike KA Date C Kikuchi S Tamakoshi A Iso H;JACC Study group 《Atherosclerosis》2008,198(2):412-418
Evidence for association between serum total homocysteine (tHcy) level and cardiovascular disease is limited in Asian populations. We conducted a nested case-control study under JACC Study. A total of 39,242 subjects aged 40-79 years provided serum samples at baseline surveys between 1988 and 1990. Control subjects were selected by matching for sex, age, community and year of serum storage. Serum tHcy levels were measured by high-performance liquid chromatography. During the 10-year follow-up, there were 444 deaths due to total cardiovascular disease, including 310 total stroke (131 hemorrhage and 101 ischemic strokes) and 134 coronary heart diseases. The risks of mortality from ischemic stroke, coronary heart disease, and total cardiovascular disease were significantly higher in individuals with the highest serum tHcy quartile (>or=15.3micromol/L) than in those with the lowest quartile (<10.5micromol/L); the respective multivariable odds ratios (95% CI) were 4.35 (1.12-16.9), 3.40 (1.17-9.86), and 1.68 (1.02-2.77). The multivariable odds ratios associated with a 5-micromol/L increase in tHcy were 1.49 (1.01-2.18), 2.01 (1.21-3.35), and 1.15 (1.00-1.32), respectively. High serum tHcy levels were associated with increased mortality from ischemic stroke, coronary heart disease and total cardiovascular disease among Japanese. 相似文献
59.
Shunsuke Kasai Hitoshi Hino Akio Shiomi Hiroyasu Kagawa Shoichi Manabe Yusuke Yamaoka Shunichiro Kato Marie Hanaoka Yusuke Kinugasa 《Asian journal of endoscopic surgery》2021,14(4):803-806
We present a very rare case of rectal cancer in a patient with situs inversus totalis (SIT), which is a complete transposition of the thoracic and abdominal viscera. A woman in her 60s visited a local hospital reporting bloody stool and was diagnosed with upper rectal cancer and SIT. We made careful preoperative preparations for the congenital anomaly, and robotic-assisted high anterior resection with D3 lymph node dissection was performed. Although we adopted an unusual six-port placement, the operation was performed safely and efficiently without any adverse events. The patient recovered uneventfully. The pathological specimen was classified as pT3N2bM0 with negative resection margins. Robotic-assisted surgery is advantageous for rectal cancer treatment even when anatomical abnormalities make the surgical procedure more difficult. 相似文献
60.
Hiroyasu?KagawaEmail author Yusuke?Kinugasa Akio?Shiomi Tomohiro?Yamaguchi Syunsuke?Tsukamoto Hiroyuki?Tomioka Yushi?Yamakawa Sumito?Sato 《Surgical endoscopy》2015,29(4):995-1000