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31.
目的:本研究的目的是观察注射疗法及复合小针刀疗法治疗肌筋膜疼痛综合征对自主神经系统功能的影响。方法:选择40例诊断明确的肌筋膜疼痛病人,随机分为两组,每组20例。Ⅰ组:采用注射疗法治疗;IS组:采用注射疗法加小针刀治疗。观察两组病人治疗前后心率变异(HRV)的频域变化,低频LF、超低频LLF、高频HF、低高频比LF/HF及心率变异指数HR-Ⅵ;用视觉模拟评分法(VAS)评定治疗前后疗效并随访观察其远期疗效。结果:①HRV频域指标组内比较:LF、LLF、HF以及HRVI治疗前舆治疗后1min比较有显着性差异(P〈0.05),与5min、10min比较有非常显着性差异(P〈0.01)。LF/HF治疗前与治疗后5min、10min比较有显着性差异(P〈0.05)。组间治疗后1、5、10min,两两比较无显着性差异。②组间比较:病人治疗后临床症状、VAS评分均较治疗前降低.治疗前后IS组有非常显着性差异(P〈0.01)。两组VAS降低率有非常显着性差异(P〈0.01)。③回访病例中,两组治疗有效率比较有显着性差异(P〈0.05)。结论:注射疗法以及复合小针刀疗法均可有效改善肌筋膜疼痛病人的自主神经功能,其机制可能是通过调节、稳定自主神经系统功能达到缓解疼痛。注射疗法复合小针刀疗法的远期疗效优于单纯注射疗法。 相似文献
32.
COPD机械通气病人下呼吸道感染致病菌分布特点 总被引:1,自引:0,他引:1
①目的 探讨慢性阻塞性肺病(COPD)病人机械通气后下呼吸道感染致病菌的特点。②方法 取32例COPD并发呼吸衰竭行机械通气病人下呼吸道分泌物做痰细菌学培养,同时做药物敏感试验。③结果 32例病人共分离出菌株76株,阳性率71.7%,其中混合感染10例次。其中革兰阴性杆菌(GNB)58株,占76.3%;阳性球菌10株,占13.2%;真菌8株,占10.5%。常见致病菌以铜绿假单胞菌、鲍曼不动杆菌和肺炎杆菌为主,GNB中铜绿假单胞菌和不动杆菌的耐药率高。④结论 COPD应用机械通气病人下呼吸道感染以革兰阴性杆菌为主,耐药性高。 相似文献
33.
34.
NOS1 polymorphism is associated with atopy but not exhaled nitric oxide levels in healthy children 总被引:1,自引:0,他引:1
May Ali Siew-Kim Khoo Stephen Turner Stephen Stick Peter Le Souëf Peter Franklin 《Pediatric allergy and immunology》2003,14(4):261-265
Exhaled nitric oxide (FENO ) is raised in atopy. The mechanism for this is unclear. The aim of this study was to investigate whether the number of AAT repeats in intron 20 of the NOS1 gene, recently associated with variations in FENO in adults with asthma and cystic fibrosis, was associated with the raised FENO in healthy atopic children. Eighty-seven healthy children (44 girls, 42 atopic, age range 6–18 years) underwent measurements of FENO , spirometry, airway responsiveness and skin prick testing. Genotyping was carried out to determine the number of AAT repeats. There was no association between the number of AAT repeats and FENO in either the whole sample of healthy children (n = 87) or in the subsample of healthy atopics (n = 42). However, a greater number of atopic children had two high repeat alleles compared with non-atopic children (33.3% vs. 13.6%, respectively, p = 0.03). This suggests that variations in the NOS1 gene may contribute to atopy without this relationship being reflected by FENO . 相似文献
35.
后程三维适形放疗治疗Ⅲ期非小细胞肺癌临床研究 总被引:5,自引:0,他引:5
OBJECTIVE: To evaluate the therapeutic efficacy and radiation complications of late course three-dimensional conformal radiotherapy (3DCRT) in patients with stage III non-small cell lung cancer (NSCLC). METHODS: Eighty-six patients with stage III NSCLC were randomly divided into group A (n=42) receiving conventional radiotherapy at the total dose of 66 to 70 Gy in 33 to 35 fractions completed in 6 to 7 weeks and group B (n=44) with late course 3DCRT at the dose of 24-30 Gy in 6 fractions (400-500 cGy per fraction every other day) after 40 Gy conventional radiotherapy, completed in 5 to 6 weeks. RESULTS: The efficacy rates in groups A and B were 55.0% and 82.9%, and the complete remission rates were 7.5% and 31.7% respectively, showing significant difference between the two groups (P<0.05). The 1- and 2-year survival rates of the patients in group A and B were 62.5% vs 78.0%, and 40.0% vs 53.7% respectively, without significant difference (P>0.05). The median survival time in groups A and B were 11.4 months and 19.8 months respectively. The major radiation complications observed in the two groups were grade I to II acute radiation esophagitis and hematopoietic toxicity. The later stage radiation complications in the two groups were grade I to II radiation lung fibrosis, occurring at a similar rate between the two groups. CONCLUSION: Late course 3DCRT produces better therapeutic effects than conventional radiotherapy in patients with stage III NSCLC. 相似文献
36.
本研究法用γ线吸收法,测量了87例60岁以上正常老年人的骨密度,以观察中度高原地区老年人骨密度的变化规律,结果提示:中度高原地区骨密度变化趋势与平原地区一样,密度与年龄成反比,女性骨量比男性丢失快且早,70岁以上男女之间差别缩小,70岁以下组平原地区测定值与高原存在显著差异(P〈0.001),造成差异的原因我们认为与高原地区紫外线强,食物及人接受的照射剂量比平原高,继而摄取及皮肤转化钙调节类激素增 相似文献
37.
应用一次法口服4mg/kg的米非司酮(RU486)观察17例单纯性肥胖和7例疑似库欣组的病人服药前后的反应,并与10例正常人以及29例库欣综合征病人进行比较,发现库欣综合征病人服药以后,血F24小时尿F及血ACTH均无显著性变化(P〉0.05),而其他三组各指标均升高(P〈0.01)。并得出鉴别库欣综合征与非库欣综合征的标准为:血F增加的百分比为30%24小时尿F增加百分比为18%,ACTH增加百 相似文献
38.
39.
The effect of prolonged, 22 h long, intracerebroventricular (i.c.v.) infusion of corticotropin-releasing hormone (CRF) on plasma cortisol, corticosterone and electrolyte concentrations, mean arterial blood pressure (MAP) and heart rate (HR) were investigated in conscious rabbits. During i.c.v. infusion of CRF, 1 and 3 μ/h, at a rate of 17 μl/h, plasma cortisol and corticosterone concentrations rose to the level noted after ACTH stimulation in rabbits. Plasma [Na] did not change, but plasma [K] was reduced and plasma osmolality increased during the infusion of CRF, 3 μ/h. MAP and HR, recorded continuously during i.c.v. infusion of CRF, changed only with the higher dose of CRF: MAP was elevated during the first 5 h of infusion, and then returned to the control level. HR was lower than control at the end of the first hour of infusion and again between 9 and 15 h of infusion. The prolonged rise of CRF concentration in the brain induced a sustained rise in circulating adrenal steroid hormones. MAP did not increase to the level noted after bolus i.c.v. injection of CRF and the rise in MAP was not sustained. 相似文献
40.
目的 :研究SRS2 0 0X 刀治疗系统治疗靶点定位的精确度。方法 :应用人体头颅模型内特定标记物测定CT定位的精度 ,用胶片法测定二次等中心系统精度和总的治疗精度。结果 :BRW头环CT定位精度为 0 .65mm ,最大误差为 1 .0 9mm ;SRS2 0 0二次等中心系统误差为 0 .1 9mm ;总治疗误差理论计算值为0 .68mm ,胶片法检测值为 1 .43mm。结论 :X 刀治疗系统精确度已达到放射外科质量控制要求。 相似文献