全文获取类型
收费全文 | 2561篇 |
免费 | 106篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 67篇 |
妇产科学 | 10篇 |
基础医学 | 243篇 |
口腔科学 | 39篇 |
临床医学 | 159篇 |
内科学 | 661篇 |
皮肤病学 | 32篇 |
神经病学 | 201篇 |
特种医学 | 130篇 |
外科学 | 604篇 |
综合类 | 28篇 |
预防医学 | 52篇 |
眼科学 | 76篇 |
药学 | 94篇 |
中国医学 | 4篇 |
肿瘤学 | 270篇 |
出版年
2023年 | 15篇 |
2022年 | 23篇 |
2021年 | 55篇 |
2020年 | 30篇 |
2019年 | 42篇 |
2018年 | 61篇 |
2017年 | 47篇 |
2016年 | 47篇 |
2015年 | 55篇 |
2014年 | 71篇 |
2013年 | 91篇 |
2012年 | 163篇 |
2011年 | 164篇 |
2010年 | 97篇 |
2009年 | 105篇 |
2008年 | 133篇 |
2007年 | 130篇 |
2006年 | 145篇 |
2005年 | 167篇 |
2004年 | 167篇 |
2003年 | 157篇 |
2002年 | 163篇 |
2001年 | 31篇 |
2000年 | 41篇 |
1999年 | 28篇 |
1998年 | 44篇 |
1997年 | 22篇 |
1996年 | 32篇 |
1995年 | 25篇 |
1994年 | 23篇 |
1993年 | 29篇 |
1992年 | 32篇 |
1991年 | 30篇 |
1990年 | 23篇 |
1989年 | 25篇 |
1988年 | 19篇 |
1987年 | 19篇 |
1986年 | 10篇 |
1985年 | 11篇 |
1983年 | 8篇 |
1981年 | 9篇 |
1980年 | 14篇 |
1979年 | 9篇 |
1978年 | 5篇 |
1977年 | 9篇 |
1976年 | 5篇 |
1975年 | 7篇 |
1973年 | 6篇 |
1970年 | 5篇 |
1969年 | 5篇 |
排序方式: 共有2688条查询结果,搜索用时 140 毫秒
51.
52.
Kinuyo Kawabata Makoto Uchikawa Hitoshi Ohto Hiroyasu Yasuda Hatsue Tsuneyama Hideaki Tsuchida Shoichi Ito 《Transfusion medicine reviews》2014,28(1):23-28
We encountered a broadly reactive red cell alloantibody in 1991, reacting unlike any other known antibody, and named it anti-KANNO after the first patient. A total of 28 cases of anti-KANNO in the Japanese literature were reviewed. To distinguish KANNO from other antibodies against high-frequency antigens, including anti-JMH, anti-Ch/Rg, and anti-Jra, we conducted serologic studies with proteolytic enzyme and chemical treatments, complement sensitization against red cells, and serum neutralization techniques. Reactivity of anti-KANNO against red cells lacking high-frequency antigens and antisera to high-frequency antigens against KANNO cells were tested. Among the 28 patients, 26 were female, of whom 25 had a history of pregnancy. Red cells from patient KANNO were reactive with antisera against antigens of high frequency. Anti-KANNO reacted weakly with all cells known to lack high-frequency antigens. It reacted with 2-aminoethylisothiouronium bromide, so it can be distinguished from anti-JMH. Differences among anti-KANNO, anti-Ch/Rg, and anti-Jra emerged with enzyme-treated cells, complement-sensitized cells, and the addition of normal serum. As yet, there are no reports of hemolytic transfusion reaction or hemolytic disease of the fetus and newborn attributable to anti-KANNO. It appears that anti-KANNO is a newly characterized antibody more likely stimulated by pregnancy than by transfusion and with little or no clinical significance. Further surveillance and investigation of anti-KANNO, its antigen biochemistry, and its genetics are warranted. 相似文献
53.
54.
Daisuke Miyaki Hiroshi Aikata Hiromi Kan Hatsue Fujino Ayako Urabe Keiichi Masaki Takayuki Fukuhara Tomoki Kobayashi Noriaki Naeshiro Takashi Nakahara Tomokazu Kawaoka Akira Hiramatsu Shoichi Takahashi Masaki Ishikawa Hideaki Kakizawa Kazuo Awai Kazuaki Chayama 《Journal of gastroenterology and hepatology》2013,28(12):1834-1841
55.
Shinji Uchida Naotsugu Obayashi Hiroshi Yamanari Katashi Matsubara Daiji Saito Shoichi Haraoka 《Heart and vessels》1992,7(3):164-167
Summary We report a case of a papillary fibroelastoma originating from the left ventricular endocardium in the outflow tract which was discovered by echocardiography in an asymptomatic patient. Two echocardiographic features were observed: (1) the tumor surface was smooth, and characteristic papillary formation was not detected; and (2) the outline of the mass was clearly defined as a dense echo, with the central, radiolucent, portion surrounded by a highly refractive linear echo at the level of the maximum diameter of the mass. The excised tumor was covered with a gelatinous substance that masked multiple papillae on the surface, but its echolucent center could not be explained by the pathology of the tumor which was solid centrally. Our case indicates that a papillary fibroelastoma may sometimes show echocardiographic findings similar to those of a myxoma, although other investigators have not noted the smooth surface and the echolucent center makes it indistinguishable from a myxoma. Thus, in some cases, it is difficult to distinguish papillary fibroelastoma from myxoma by echocardiography. 相似文献
56.
Shuichi Taniguchi Tsunefumi Shibuya Eiji Morioka Takashi Okamura Seiichi Okamura Shoichi Inaba† Yoshiyuki Niho 《British journal of haematology》1988,68(4):473-477
A patient with pure red cell aplasia (PRCA) and autoimmune haemolytic anaemia (AIHA), associated with a thymoma which had already been removed, was studied in order to investigate the pathogenesis of PRCA and AIHA. The autoantibody eluted from the surface of the patient's red blood cells (RBC) reacted with the large E antigen of the Rh complex. Immunoglobulin-G (IgG) purified from the patient's serum suppressed CFU-E and BFU-E but not CFU-GM colony formation in the presence of complement. This antibody was not adsorbed with large E antigen. T-lymphocytes in the bone marrow suppressing autologous CFU-E and BFU-E colonies were demonstrated. Thus, three distinct immunological disorders on erythropoiesis were present in this patient with PRCA and AIHA associated with thymoma in a thymectomized state. 相似文献
57.
Nogami A Sugiyasu A Tada H Kurosaki K Sakamaki M Kowase S Oginosawa Y Kubota S Usui T Naito S 《Journal of cardiovascular electrophysiology》2008,19(7):681-688
Introduction: Although successful ablation of ventricular tachycardia (VT) is feasible in arrhythmogenic right ventricular cardiomyopathy (ARVC), long-term recurrence is common. The aim of this study was to assess the usefulness of a change in the isolated delayed component (IDC) as an endpoint of the catheter ablation in ARVC.
Methods and Results: Eighteen patients (48 ± 11 years) with ARVC were studied. Detailed endocardial mapping of the right ventricle (RV) was performed during sinus rhythm. IDCs were recorded in 16 patients and the latest IDCs were related to the VT circuit. Catheter ablation was carried out in the areas with the IDCs. At the end of the session, the IDC was electrically dissociated in one, disappeared in five, exhibited second-degree block in one, was significantly delayed (≥50 ms) in three, and remained unchanged in six. The change in the IDC was correlated with the change in the type II/III late potentials in the signal-averaged electrocardiography (ECG) and the inducibility of the clinical VT after the ablation. During a follow-up of 61 ± 38 months, VT recurred in six. The patients with a changed IDC had a significantly lower VT recurrence than those with no IDC or an unchanged IDC (P < 0.02).
Conclusion: In patients with ARVC, (1) the IDCs during sinus rhythm are related to the clinical VT and can be a target for the ablation, (2) a change in the IDC can be used as an endpoint, and (3) qualitative analyses of the serial signal-averaged ECGs may be useful for the long-term follow-up. 相似文献
Methods and Results: Eighteen patients (48 ± 11 years) with ARVC were studied. Detailed endocardial mapping of the right ventricle (RV) was performed during sinus rhythm. IDCs were recorded in 16 patients and the latest IDCs were related to the VT circuit. Catheter ablation was carried out in the areas with the IDCs. At the end of the session, the IDC was electrically dissociated in one, disappeared in five, exhibited second-degree block in one, was significantly delayed (≥50 ms) in three, and remained unchanged in six. The change in the IDC was correlated with the change in the type II/III late potentials in the signal-averaged electrocardiography (ECG) and the inducibility of the clinical VT after the ablation. During a follow-up of 61 ± 38 months, VT recurred in six. The patients with a changed IDC had a significantly lower VT recurrence than those with no IDC or an unchanged IDC (P < 0.02).
Conclusion: In patients with ARVC, (1) the IDCs during sinus rhythm are related to the clinical VT and can be a target for the ablation, (2) a change in the IDC can be used as an endpoint, and (3) qualitative analyses of the serial signal-averaged ECGs may be useful for the long-term follow-up. 相似文献
58.
59.
Metachronous solitary mediastinal lymph node metastases of hepatocellular carcinoma treated by video‐assisted thoracic surgery twice: Report of a case
下载免费PDF全文
![点击此处可从《Asian journal of endoscopic surgery》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Masatake Taniguchi Masanobu Hyodo Kenji Tezuka Shoichi Shinohara Hirofumi Hayashi Yasuhiro Inoue Hirotake Satoh Munetoshi Tsukahara Alan Kawarai Lefor Masaki Okada Yoshikazu Yasuda 《Asian journal of endoscopic surgery》2018,11(1):64-67
Solitary mediastinal lymph node metastasis of hepatocellular carcinoma (HCC) is rare. We report a case of metachronically solitary mediastinal metastases of HCC treated by video‐assisted thoracic surgery (VATS) twice. A 66‐year‐old man underwent repeated laparoscopic radiofrequency ablation or trans‐arterial catheter chemo‐embolization against HCC for more than 10 years. The level of alpha fetoprotein protein was elevated, and radiological modalities including FDG‐PET revealed solitary mediastinal tumor metachronically. VATS was performed bilaterally twice. The postoperative course was uneventful and there had no recurrence of extra‐hepatic metastases and tumor markers are within normal limits at 18 months after second VATS. VATS is a minimally invasive and useful procedure for solitary mediastinal lymph node metastasis of HCC. If primary HCC was controlled and lymph node metastasis was solitary, mediastinum lymphadenectomy using VATS might give good short and long term results. 相似文献
60.
Toko Maehara Kenjiro Matsumoto Kazuhide Horiguchi Makoto Kondo Satoshi Iino Shunji Horie Takahisa Murata Hirokazu Tsubone Shoichi Shimada Hiroshi Ozaki Masatoshi Hori 《British journal of pharmacology》2015,172(4):1136-1147