DFAspike: a new computational proposition for efficient recognition of epileptic spike in EEG

An automated method has been presented for the detection of epileptic spikes in the electroencephalogram (EEG) using a deterministic finite automata (DFA) and has been named as DFAspike. EEG data (sampled, 256 Hz) files are the inputs to the DFAspike. The DFAspike was tested with different data files containing epileptic spikes. The obtained recognition rate of epileptic spike was 99.13% on an average. This system does not require any kind of prior training or human intrusion. The result shows that the designed system can be very effectively used for the detection of spikes present in the recorded EEG signals.     

A comparison of maternal and perinatal outcome between in vitro fertilization and spontaneous dichorionic-diamniotic twin pregnancies

Objective: To compare the maternal and neonatal outcome of dichorionic diamniotic in vitro fertilization (IVF) twin and spontaneous twin pregnancies.

Material and methods: Maternal and fetal data of all consecutive dichorionic-diamniotic twin pregnancies delivered in our institution between January 2009 and May 2015 were abstracted from medical records and pregnancy outcome of IVF twin was compared to spontaneous twin.

Results: Overall 708 twin pregnancies (449 IVF and 259 spontaneous) were included. Women in the IVF group were 2 years older and more frequently nulliparous. The rate of pregnancy induced hypertension and preeclampsia (PIH/PET) was three times higher in the IVF group than in the spontaneous group. The rate of preterm births, before 37 weeks of gestation and the rate of cesarean section were higher in the IVF group. These results were confirmed by multivariate analysis. The neonatal outcome was similar in both the groups except for a lower mean newborn birthweight in the IVF group.

Conclusion: Women with IVF twins are at a significantly higher risk of having preterm births, PIH/PET and cesarean section but there was no significant adverse effect on neonatal outcome except for a lower mean newborn birth weight.     

Unusual ankle fracture: A case report and literature review

Fractures of the talus are uncommon, and talar body fractures in the sagittal plane are still rarer. The aim of its treatment is urgent anatomic reduction to restore congruency of the ankle and to reduce the risk of avascular necrosis by preserving any remaining blood supply. We report the case of a body talar fracture in sagittal plane associated with fracture of the medial malleolus in a young adult; the mechanism of the fracture was plantar hyperflexion, internal rotation and axial compression. We perform an open reduction and stabilization with two screws for the talus and screw the medial malleolus. At 14 months following the injury patient had good range of movement with little pain. The mechanism is discussed along with a literature review.     

Kuwaitimycin, effect on synthesis of lipids in Bacillus subtillis cells.

The effects exerted by kuwaitimycin on synthesis of lipids as well as some metabolic activities of Bacillus subtilis were studied. The antibiotic not only arrested the inocrporation of 14C-acetate into the microbial lipids but also altered the fatty acids pattern, contents of i-C 15, a-C 15, i-C 17 and a-C 17 WERE MARKEDLY REDUCED, CONCOMITANT WITH AN INCREASE IN THE CONtents of i-C 14 AND N-C 14. Moreover, the rates of synthesis of phospholipids were decreased by the drug, especially that of phosphatidyl ethanolamine.     

某院2010-2013年非甾体抗炎药物临床利用情况分析

目的：为有效反映非甾体抗炎药在某院的临床应用情况,分析其临床应用趋势,提高非甾体抗炎药应用的安全性、合理性和经济性,从经济学的角度对某院2010-2013年非甾体抗炎药物临床使用情况进行药物利用研究（DUR）。方法：采用回顾性调查方法,结合用药金额排序法、用药频度分析法、日均费用分析法和药物利用指数分析法等研究方法,对某院2010-2013年非甾体抗炎药的临床使用情况进行统计分析。结果：该院非甾体抗炎药销售金额每年小幅度增长,阿司匹林、美洛昔康等用药频度较高,除部分特异性 COX-2抑制剂外,各类常用非甾体抗炎药日均费用较低但部分药物的药物利用度不高。结论：具有选择性的非甾体抗炎药成为新的用药趋势,提高非甾体抗炎药的利用度是今后医院改革的工作重点。