全文获取类型
收费全文 | 2976篇 |
免费 | 144篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 69篇 |
儿科学 | 239篇 |
妇产科学 | 23篇 |
基础医学 | 258篇 |
口腔科学 | 60篇 |
临床医学 | 162篇 |
内科学 | 575篇 |
皮肤病学 | 91篇 |
神经病学 | 213篇 |
特种医学 | 87篇 |
外科学 | 503篇 |
综合类 | 332篇 |
一般理论 | 1篇 |
预防医学 | 100篇 |
眼科学 | 115篇 |
药学 | 114篇 |
1篇 | |
中国医学 | 5篇 |
肿瘤学 | 178篇 |
出版年
2022年 | 25篇 |
2021年 | 69篇 |
2020年 | 34篇 |
2019年 | 50篇 |
2018年 | 55篇 |
2017年 | 35篇 |
2016年 | 42篇 |
2015年 | 96篇 |
2014年 | 108篇 |
2013年 | 152篇 |
2012年 | 150篇 |
2011年 | 178篇 |
2010年 | 142篇 |
2009年 | 103篇 |
2008年 | 141篇 |
2007年 | 162篇 |
2006年 | 169篇 |
2005年 | 102篇 |
2004年 | 115篇 |
2003年 | 93篇 |
2002年 | 109篇 |
2001年 | 71篇 |
2000年 | 63篇 |
1999年 | 62篇 |
1998年 | 49篇 |
1997年 | 42篇 |
1996年 | 34篇 |
1995年 | 24篇 |
1994年 | 23篇 |
1993年 | 14篇 |
1992年 | 49篇 |
1991年 | 40篇 |
1990年 | 53篇 |
1989年 | 46篇 |
1988年 | 38篇 |
1987年 | 33篇 |
1986年 | 26篇 |
1985年 | 23篇 |
1984年 | 23篇 |
1983年 | 18篇 |
1979年 | 22篇 |
1978年 | 16篇 |
1976年 | 19篇 |
1974年 | 20篇 |
1973年 | 19篇 |
1972年 | 17篇 |
1970年 | 12篇 |
1969年 | 19篇 |
1968年 | 23篇 |
1966年 | 12篇 |
排序方式: 共有3126条查询结果,搜索用时 15 毫秒
31.
Voluntary gaze may evoke a number of neurological phenomena such as vertigo, tinnitus, blepharoclonus, eyelid nystagmus, "facial nystagmus," involuntary laughter, and seizures. We report two patients in whom eccentric gaze evoked facial twitching and arm movement. Electroencephalograms remained unchanged during these movements. The pathogenesis of these movements is unclear but may involve ephaptic transmission. 相似文献
32.
33.
34.
35.
Sethi D Wheeler J Rodrigues LC Fox S Roderick P 《International journal of epidemiology》1999,28(1):106-112
BACKGROUND: One of the aims of the Study of Infectious Intestinal Disease (IID) in England is to estimate the incidence of IID presenting to general practice. This sub-study aims to estimate and correct the degree of under-ascertainment in the national study. METHODS: Cases of presumed IID which presented to general practice in the national study had been ascertained by their GP. In 26 general practices, cases with computerized diagnoses suggestive of IID were identified retrospectively. Cases which fulfilled the case definition of IID and should have been ascertained to the coordinating centre but were not, represented the under-ascertainment. Logistic regression modelling was used to identify independent factors which influenced under-ascertainment. RESULTS: The records of 2021 patients were examined, 1514 were eligible and should have been ascertained but only 974 (64%) were. There was variation in ascertainment between the practices (30% to 93%). Patient-related factors independently associated with ascertainment were: i) vomiting only as opposed to diarrhoea with and without vomiting (OR 0.37) and ii) consultation in the surgery as opposed to at home (OR 2.18). Practice-related factors independently associated with ascertainment were: i) participation in the enumeration study component (OR 1.78), ii) a larger number of partners (OR 0.3 for 7-8 partners); iii) rural location (OR 2.27) and iv) previous research experience (OR 1.92). Predicted ascertainment percentages were calculated according to practice characteristics. CONCLUSION: Under-ascertainment of IID was substantial (36%) and non-random and had to be corrected. Practice characteristics influencing variation in ascertainment were identified and a multivariate model developed to identify adjustment factors which could be applied to individual practices. Researchers need to be aware of factors which influence ascertainment in acute epidemiological studies based in general practice. 相似文献
36.
Sethi S Ott DA Nihill M 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》1983,10(4):343-346
During a 31-year period, 54 patients were treated for Kawasaki's disease at the Texas Heart Institute and Texas Children's Hospital. Classically, the illness is characterized by prolonged fever, conjunctivitis, oral mucosal inflammation, exanthema, and later skin desquamation and cervical lymphoadenopathy. Seventy percent of patients have electrocardiographic abnormalities consisting of prolongation of the PR and QT intervals and ST-T wave changes. Most deaths occur within 1 to 2 months after onset of the disease. The risk of coronary abnormalities and cardiac death appear to be higher in those patients under 1 year of age with prolonged fever, elevated white blood count, and erythrocyte sedimentation rate. 相似文献
37.
38.
39.
Dibenzo[a,l]pyrene-induced DNA adduction, tumorigenicity, and Ki-ras oncogene mutations in strain A/J mouse lung 总被引:1,自引:0,他引:1
Prahalad AK; Ross JA; Nelson GB; Roop BC; King LC; Nesnow S; Mass MJ 《Carcinogenesis》1997,18(10):1955-1963
Dibenzo[a,l]pyrene (DB[a,l]P), an environmental polycyclic aromatic
hydrocarbon, is the most potent carcinogen ever tested in mouse skin and
rat mammary gland. In this study, DB[a,l]P was examined for DNA adduction,
tumorigenicity, and induction of Ki-ras oncogene mutations in tumor DNA in
strain A/J mouse lung. Groups of mice received a single i.p. injection of
0.3, 1.5, 3.0, or 6.0 mg/kg DB[a,l]P in tricaprylin. Following treatment,
DNA adducts were measured at times between 1 and 28 days, while tumors were
counted at 250 days and analyzed for the occurrence of point mutations in
codons 12 and 61 of the Ki-ras oncogene. DB[a,l]P in strain A/J mouse lung
induced six major and four minor DNA adducts. Maximal levels of adduction
occurred between 5 and 10 days after injection followed by a gradual
decrease. DB[a,l]P-DNA adducts in lung tissue were derived from both anti-
and syn-11,12- dihydroxy-13,14-epoxy-
11,12,13,14-tetrahydrodibenzo[a,l]pyrene (DB[a,l]PDE) and both
deoxyadenosine (dAdo) and deoxyguanosine (dGuo) residues in DNA as revealed
by cochromatography. The major adduct was identified as a product of the
reaction of an anti-DB[a,l]PDE with dAdo in DNA. DB[a,l]P induced
significant numbers of lung adenomas in a dose- dependent manner, with the
highest dose (6.0 mg/kg) yielding 16.1 adenomas/mouse. In
tricaprylin-treated control animals, there were 0.67 adenomas/mouse. Based
on the administered dose, DB[a,l]P was more active than other environmental
carcinogens including benzo[a]pyrene. As a function of time-integrated DNA
adduct levels, DB[a,l]P induced lung adenomas with about the same potency
as other PAHs, suggesting that the adducts formed by DB[a,l]P are similar
in carcinogenic potency to other PAHs in the strain A/J mouse lung model.
Analysis of the Ki- ras mutation spectrum in DB[a,l]P-induced lung tumors
revealed the predominant mutations to be G-->T transversions in the
first base of codon 12, A-->G transitions in the second base of codon
12, and A-->T transversions in the second or third base of codon 61,
concordant with the DNA adduct profile.
相似文献
40.
Twenty-seven patients with idiopathic palmoplanter hyperhidrosis were treated with Iontotherapy over a one year period. In twenty-four cases there was a good response but maintenance therapy was required every 3-4 weeks.KEY WORDS: Iontophoresis, Palmoplanter hyperhidrosis 相似文献