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61.
Yilmaz F Sahin F Ergoz E Deniz E Ercalik C Yucel SD Kuran B 《Clinical rheumatology》2008,27(3):327-332
The aim of this study is to evaluate comparatively the life quality of patients with knee osteoarthritis (KO), shoulder impingement
syndrome(SIS), fibromialgia(FM), or osteoporosis(OP) using SF 36 and establish the impact of these diseases on quality of
life (QoL). A total of 193 patients with one of the above-mentioned different diagnoses completed SF 36 scale. The diseases
were compared to each other with SF 36 subgroups scores. There were significant differences among patients with KO and SIS,SIS
and FM with respect to all SF 36 subgroups scores. According to these assessments, QoL of KO and FM patients was worst than
that of SIS. The QoL scores of KO patients were worse than those of FM patients considering the physical function, while QoL
scores of FM patients were lower than those of KO patients with respect to their general well-being. Scores of physical function
and pain in KO patients were lower than those of OP patients. In domains of social functioning, emotional role, energy, pain,
and general health condition QoL of FM patients was worse than that of OP patients. Quality of life of SIS patients was less
affected than the patients of the other disease groups. In spite of their young age, FM patients appear to be the group with
the worst quality of life scores. 相似文献
62.
Location of Golgi membranes with reference to dividing
nuclei in syncytial Drosophila embryos. 总被引:3,自引:1,他引:3
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J Ripoche B Link J K Yucel K Tokuyasu V Malhotra 《Proceedings of the National Academy of Sciences of the United States of America》1994,91(5):1878-1882
The role of cytoskeletal elements in thecellularization of syncytial Drosophila embryos is becoming evident; however,the distribution and role of organelles such as the Golgi complex, essential formembrane biogenesis, remain unknown. We have cloned a Golgi-membrane-associatedpolypeptide, beta-COP, from Drosophila. Immunocytochemical studies of syncytialDrosophila embryos with anti-Drosophila beta-COP antibody reveal that Golgimembranes are spatially segregated from the rapidly dividing nuclei. In earlyembryos, the Golgi membranes are located in the embryonic cortex and nuclei areconfined to the core. This distribution of Golgi membranes may serve inpreparation of the embryonic cortex for the accommodation of nuclei upon theireventual migration to the cortex and in biogenesis of the excessive plasmamembrane needed for cellularization of syncytial embryos. 相似文献
63.
Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules. 总被引:14,自引:4,他引:14
D D Von Hoff D R Needham-VanDevanter J Yucel B E Windle G M Wahl 《Proceedings of the National Academy of Sciences of the United States of America》1988,85(13):4804-4808
Amplification of genes can sometimes be detected by molecular hybridization but not by cytogenetic methods, suggesting that in some cases the units of amplification may be too small to be detected by light microscopy. The experiments reported here investigate whether submicroscopic amplification units are present in early passages of the human tumor cell lines HL-60 and COLO 320. The results show that such cells do contain submicroscopic, extrachromosomal, supercoiled circular molecules harboring MYC genes. The molecules in HL-60 are approximately 250 kilobase pairs (kbp), while those in COLO 320 are 120-160 kbp. The extrachromosomal molecules in HL-60 are shown to replicate semiconservatively and approximately once in one cell cycle. We propose that these submicroscopic elements are precursors of double-minute chromosomes, the usual extrachromosomal manifestation of gene amplification, since both are structurally similar and replicate autonomously. 相似文献
64.
65.
Oxidative Status,Inflammation, and Postoperative Atrial Fibrillation With Metoprolol vs Carvedilol or Carvedilol Plus N‐Acetyl Cysteine Treatment
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66.
Mehmet Serdar Kutuk Ali Yikilmaz Mahmut Tuncay Ozgun Mehmet Dolanbay Mehmet Canpolat Semih Uludag Gulsum Uysal Mustafa Tas Karakukcu Musa 《Child's nervous system》2014,30(3):411-418
Background
The aim of this study was to present our experience with six cases of fetal intracranial hemorrhage (ICH) in terms of prenatal diagnostic features, and postnatal outcome.Methods
The database of prenatal diagnosis unit was searched for antenatally diagnosed ICH cases. Maternal characteristics, ultrasound (US), and magnetic resonance imaging (MRI) findings, clinical course, and postnatal outcome were noted.Results
We evaluated six consecutive cases of fetal ICH. One case was terminated at 24 weeks, and remaining five cases were delivered between 34 and 38 weeks. Five cases (5/6) had intraventricular, and one (1/6) had intraparenchymal hemorrhage. Hemorrhages were right sided in five cases (5/6), left sided in one case (1/6). Dilated and echogenic ventricular wall were the common US findings. No predisposing factor was detected in four of the cases, and intrauterine growth restriction was an underlying factor in two fetuses. Intrauterine progression of the hydrocephaly, and parenchymal thinning was seen in four cases (4/6). In three of four cases (3/4) with progressive grade 3–4 hemorrhage and hydrocephaly, postnatal outcome were dismal, and one case had mild neurological impairment at three months. In one case which had non-progressive mild ventriculomegaly, the lesion regressed after 4 weeks, and had normal short-term outcomeConclusion
Fetal ICH can be accurately identified and categorized by antenatal sonography, and fetal MRI. Although intrauterine regression or normal short-term postnatal outcome is possible, the outcome is usually poor for fetuses with high grade and/or progressive lesions. Therefore, further studies assessing long-term postnatal outcome are needed 相似文献67.
Ahmet Fikret Yucel Ahmet Pergel Ibrahim Aydin Dursun Ali Sahin 《The Indian journal of surgery》2014,76(2):154-155
Defunctioning stoma is a commonly used colorectal surgical procedures. The stomal complications recorded are usually classified as early and late complications. Parastomal hernia is a common complication of stomal surgery. We present a very rare stoma-related complication developed after parastomal hernia and described parastomal evisceration. 相似文献
68.
Leyla Guler Murat Tavlasoglu Orhan Yucel Adem Guler Mehmet Ali Sahin Mustafa Kurkluoglu Yusuf Sirin Ayse Eken Mehmet Gamsizkan Mehmet Dakak Sedat Gurkok Onur Genc 《Journal of anesthesia》2014,28(3):347-353
Purpose
Taurine, the major intracellular free amino acid found in high concentrations in mammalian cells, is known to be an endogenous antioxidant and a membrane-stabilizing agent. It was hypothesized that taurine may be effective in reducing ischemia–reperfusion injury after lung transplantation and an experimental study was conducted in a rat model.Methods
The number of Sprague–Dawley rats used in the study was 35. Animals were randomized into five groups of 7 rats each, including control, donor I, donor II, ischemia–reperfusion injury, and treatment groups. All animals were exposed to the same experimental conditions in the preoperative period. Rats were fixed in a supine position after the induction. After the rats were shaved, a left pneumonectomy was performed following sternotomy in control, donor I, and donor II groups. The harvested grafts in donor I and donor II groups were transplanted to the rats of the ischemia–reperfusion group and treatment group, respectively. However, taurine was administered intraperitoneally for 3 days before the harvesting procedure in donor II. All harvested lungs were kept in a Euro-Collins solution at +4 °C for 24 h in a half-inflated manner. After harvesting and transplantation, lungs were sampled for histopathological and biochemical analysis.Results
Malondialdehyde and superoxide dismutase, glutathione peroxidase, and catalase levels were lower in the treatment group than the other groups (p < 0.05). Histopathological findings were better in treatment group than the ischemia–reperfusion group (p < 0.05).Conclusion
It was demonstrated that donor treatment with taurine resulted in preservation of transplanted lung tissue in respect to histopathological and biochemical findings. 相似文献69.
70.
Aki Semih Özden Ali Veysel Alptekin Hasan Kerem Öncü Alptekin Jülide 《Manuelle Medizin》2020,58(4-5):237-245
Manuelle Medizin - The current study was designed to compare the short-term effects of chiropractic applications (diversified technique) and dry needling on chronic mechanical neck pain.... 相似文献