Phone and e-mail counselling are effective for weight management in an overweight working population: a randomized controlled trial

Background  

The work setting provides an opportunity to introduce overweight (i.e., Body Mass Index ≥ 25 kg/m²) adults to a weight management programme, but new approaches are needed in this setting. The main purpose of this study was to investigate the effectiveness of lifestyle counselling by phone or e-mail on body weight, in an overweight working population. Secondary purposes were to establish effects on waist circumference and lifestyle behaviours, and to assess which communication method is the most effective.     

Effects of SIRPalphal on liver regeneration after partial hepatectomy in rat

BACKGROUND：SIRPalphal is well known as a negative regulator for cell proliferation through the regulation of the activity of receptor tyrosine kinase with ITAM motif. No investigation to data was undertaken on SIRPalphal involving liver regeneration. MATERIALS AND METHODS: Adult male Sprague-Dawley rats underwent approximately 700% partial hepatectomy (PH) or sham operation (SO). Liver specimens were collected at 2，6，12，24，30，48，72，120，168,and 240 h after PH or SO.     

Do normal leucocyte count and C‐reactive protein value exclude acute appendicitis in children?

The present study aimed to determine the role of leucocyte count and C-reactive protein (CRP) measurements in the diagnosis of acute appendicitis in children. In particular, children with acute appendicitis but normal leucocyte count and CRP level were sought. The present study protocol was identical to those used in earlier studies on adult patients with suspected acute appendicitis. The mean preoperative leucocyte count and CRP value in 100 consecutive children with an uninflamed appendix at appendicectomy (group A) and in 100 consecutive patients with acute appendicitis (group B) were calculated. The numbers of patients with (i) both values normal, (ii) only leucocyte count raised, (iii) only CRP level raised, and (iv) both values raised were calculated in both groups A and B. Leucocyte count effectively (p     

杭州市3岁儿童乳牙龋齿患病情况调查

为早发现、早预防儿童龋齿的发生和发展 ,了解我市儿童早期的乳牙龋齿患病情况 ,于 1998年 ,对杭州市幼儿园进行随机抽样 ,在 3岁儿童中作龋齿调查 ,现报道如下。对象与方法1　对象　对杭州市所有的幼儿园分 5个城区 (拱墅、上城、下城、西湖、江干 )随机抽样 ,每个城区随机抽取 2～3所幼儿园 ,对纳入的幼儿园中所有过了 3岁生日 ,尚未到4岁生日的幼儿进行口腔检查。2　方法　口腔检查由一位副主任医师在自然光线下 ,使用标准器械 ,严格按照ＷＨＯ (1997)龋齿诊断标准[1 ] 进行检查。另一位医师配合 ,按每个牙齿龋蚀情况、龋齿类型(分四型 :…     

Bench-to-bedside review: Angiopoietin signalling in critical illness – a future target?

Multiple organ dysfunction syndrome (MODS) occurs in response to major insults such as sepsis, severe haemorrhage, trauma, major surgery and pancreatitis. The mortality rate is high despite intensive supportive care. The pathophysiological mechanism underlying MODS are not entirely clear, although several have been proposed. Overwhelming inflammation, immunoparesis, occult oxygen debt and other mechanisms have been investigated, and – despite many unanswered questions – therapies targeting these mechanisms have been developed. Unfortunately, only a few interventions, usually those targeting multiple mechanisms at the same time, have appeared to be beneficial. We clearly need to understand better the mechanisms that underlie MODS. The endothelium certainly plays an active role in MODS. It functions at the intersection of several systems, including inflammation, coagulation, haemodynamics, fluid and electrolyte balance, and cell migration. An important regulator of these systems is the angiopoietin/Tie2 signalling system. In this review we describe this signalling system, giving special attention to what is known about it in critically ill patients and its potential as a target for therapy.