全文获取类型
| 收费全文 | 2067619篇 |
| 免费 | 158532篇 |
| 国内免费 | 4134篇 |
专业分类
| 耳鼻咽喉 | 29143篇 |
| 儿科学 | 71801篇 |
| 妇产科学 | 58206篇 |
| 基础医学 | 296944篇 |
| 口腔科学 | 56999篇 |
| 临床医学 | 184741篇 |
| 内科学 | 405633篇 |
| 皮肤病学 | 46301篇 |
| 神经病学 | 163148篇 |
| 特种医学 | 81283篇 |
| 外国民族医学 | 941篇 |
| 外科学 | 314119篇 |
| 综合类 | 46941篇 |
| 现状与发展 | 1篇 |
| 一般理论 | 735篇 |
| 预防医学 | 159617篇 |
| 眼科学 | 46916篇 |
| 药学 | 151692篇 |
| 5篇 | |
| 中国医学 | 4003篇 |
| 肿瘤学 | 111116篇 |
出版年
| 2018年 | 21396篇 |
| 2017年 | 16388篇 |
| 2016年 | 18307篇 |
| 2015年 | 20737篇 |
| 2014年 | 28694篇 |
| 2013年 | 43942篇 |
| 2012年 | 59141篇 |
| 2011年 | 62911篇 |
| 2010年 | 37709篇 |
| 2009年 | 35714篇 |
| 2008年 | 59829篇 |
| 2007年 | 63764篇 |
| 2006年 | 64389篇 |
| 2005年 | 62308篇 |
| 2004年 | 60874篇 |
| 2003年 | 58731篇 |
| 2002年 | 57312篇 |
| 2001年 | 98411篇 |
| 2000年 | 101499篇 |
| 1999年 | 85947篇 |
| 1998年 | 23959篇 |
| 1997年 | 21563篇 |
| 1996年 | 21876篇 |
| 1995年 | 20937篇 |
| 1994年 | 19668篇 |
| 1993年 | 18253篇 |
| 1992年 | 68476篇 |
| 1991年 | 67089篇 |
| 1990年 | 65451篇 |
| 1989年 | 62780篇 |
| 1988年 | 57583篇 |
| 1987年 | 57176篇 |
| 1986年 | 53414篇 |
| 1985年 | 51440篇 |
| 1984年 | 38607篇 |
| 1983年 | 32557篇 |
| 1982年 | 19196篇 |
| 1981年 | 17380篇 |
| 1979年 | 34987篇 |
| 1978年 | 24817篇 |
| 1977年 | 21024篇 |
| 1976年 | 19739篇 |
| 1975年 | 21124篇 |
| 1974年 | 25026篇 |
| 1973年 | 24132篇 |
| 1972年 | 22211篇 |
| 1971年 | 20476篇 |
| 1970年 | 19136篇 |
| 1969年 | 17543篇 |
| 1968年 | 16172篇 |
排序方式： 共有10000条查询结果，搜索用时 15 毫秒
31.
32.
33.
Derrick P. Smit David Meyer Tonya M. Esterhuizen Jolanda D. F. De Groot-Mijnes 《Ocular immunology and inflammation》2019,27(2):189-196
Purpose: To use polymerase chain reaction (PCR) and Goldmann-Witmer coefficient (GWC) calculation to diagnose infectious uveitis.
Methods: Prospective cross-sectional study.
Results: Twenty-seven of 106 patients had positive PCR and/or GWC results on aqueous humor (AH) sampling and 15 of 27 (55.6%) were HIV-positive. Patients with non-anterior uveitis (NAU) were more likely to be HIV+ (p = 0.005). More than 1 possible pathogen was identified in 9 of 27 patients of whom 7 were HIV+. The final clinical diagnosis was discordant with AH findings in 9 of 27 cases. A positive EBV PCR result was associated with a discordant diagnosis (p = 0.001). All cases of herpetic anterior uveitis (42.9% HIV+) tested PCR-/GWC+ while all cases of herpetic NAU tested PCR+/GWC- (83.3% HIV+). All rubella virus cases were PCR+/GWC+.
Conclusion: PCR is useful to diagnose herpetic NAU in HIV+ patients while GWC is useful to diagnose herpetic anterior uveitis. 相似文献
34.
35.
36.
Alexandra B. Morshed Rachel G. Tabak Cynthia D. Schwarz Debra Haire-Joshu 《Journal of nutrition education and behavior》2019,51(2):237-244
Objective
To examine whether a healthy weight intervention embedded in the Parents as Teachers (PAT) home visiting program, which was previously found to improve mothers’ body mass index (BMI) and obesity-related behaviors, changed the BMI of preschool children or maternal feeding practices.Methods
This stratified randomized trial included preschool-aged children at risk for overweight whose mothers were overweight or had obesity (n?=?179). The Healthy Eating and Active Living Taught at Home (HEALTH) intervention was based on the Diabetes Prevention Program. Differences were examined using repeated-measures mixed-ANOVA models.Results
Compared with PAT usual care, the HEALTH intervention had no effect on children's BMI or maternal feeding practices. However, combined analyses showed that children's BMI percentile decreased (P??=?.007), BMI z-scores were maintained (P??=?.19), and 3 of 8 feeding practices improved over time (P < .05).Conclusions and Implications
Additional research is needed to assess the effectiveness of PAT to prevent preschool-age obesity using rigorous designs (eg, group-randomized trials) and to identify its active components. HEALTH is ready to be scaled up to prevent maternal weight gain through embedding within the national PAT program. 相似文献37.
Martin R. Späth Malte P. Bartram Nicolàs Palacio-Escat K. Johanna R. Hoyer Cedric Debes Fatih Demir Christina B. Schroeter Amrei M. Mandel Franziska Grundmann Giuliano Ciarimboli Andreas Beyer Jayachandran N. Kizhakkedathu Susanne Brodesser Heike Göbel Jan U. Becker Thomas Benzing Bernhard Schermer Martin Höhne Markus M. Rinschen 《Kidney international》2019,95(2):333-349
38.
Elizabeth D. Krebs Robert B. Hawkins J. Hunter Mehaffey Clifford E. Fonner Alan M. Speir Mohammed A. Quader Jeffrey B. Rich Leora T. Yarboro Nicholas R. Teman Gorav Ailawadi 《The Journal of thoracic and cardiovascular surgery》2019,157(4):1533-1542.e2
Objectives
Expedient extubation after cardiac surgery has been associated with improved outcomes, leading to postoperative extubation frequently during overnight hours. However, recent evidence in a mixed medical-surgical intensive care unit population demonstrated worse outcomes with overnight extubation. This study investigated the impact of overnight extubation in a statewide, multicenter Society of Thoracic Surgeons database.Methods
Records from 39,812 patients undergoing coronary artery bypass grafting or valve operations (2008-2016) and extubated within 24 hours were stratified according to extubation time between 06:00 and 18:00 (day) or between 18:00 and 6:00 (overnight). Outcomes including reintubation, mortality, and composite morbidity-mortality were evaluated using hierarchical regression models adjusted for Society of Thoracic Surgeons predictive risk scores. To further analyze extubation during the night, a subanalysis stratified patients into 3 groups: 06:00 to 18:00, 18:00 to 24:00, and 24:00 to 06:00.Results
A total of 20,758 patients were extubated overnight (52.1%) and were slightly older (median age 66 vs 65 years, P < .001) with a longer duration of ventilation (4 vs 7 hours, P < .001). Day and overnight extubation were associated with equivalent operative mortality (1.7% vs 1.7%, P = .880), reintubation (3.7% vs 3.4%, P = .141), and composite morbidity-mortality (8.2% vs 8.0%, P = .314). After risk adjustment, overnight extubation was not associated with any difference in reintubation, mortality, or composite morbidity-mortality. On subanalysis, those extubated between 24:00 and 06:00 exhibited increased composite morbidity-mortality (odds ratio, 1.18; P = .001) but no difference in reintubation or mortality.Conclusions
Extubation overnight was not associated with increased mortality or reintubation. These results suggest that in the appropriate clinical setting, it is safe to routinely extubate cardiac surgery patients overnight. 相似文献39.
Ángel Becerra Héctor Trujillo Lucía Valencia Aurelio Rodríguez‐Pérez 《Brazilian Journal of Anesthesiology》2019,69(2):200-203
Background and objectives
A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.Case report
A 41 year‐old woman suffered a car accident. At the emergency department, no abnormalities were found in ECG or chest X‐ray. Abdominal ultrasound revealed the presence of abdominal free liquid and the patient was submitted to urgent exploratory laparotomy. Nevertheless, she persisted suffering arterial hypotension and metabolic acidosis. Looking for the reason of her hemodynamic instability, intraoperative transthoracic echocardiography was performed, finding out the presence of pericardial effusion. Once the cardiac surgeon extracted pericardial clots, patient's situation improved clinically and analytically.Conclusion
Every anesthesiologist should be able to use the intraoperative echocardiography as an effective tool in order to establish the appropriate measures to promote the survival of patients suffering severe trauma. 相似文献40.