全文获取类型
收费全文 | 7439篇 |
免费 | 439篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 50篇 |
儿科学 | 296篇 |
妇产科学 | 163篇 |
基础医学 | 788篇 |
口腔科学 | 114篇 |
临床医学 | 1521篇 |
内科学 | 1285篇 |
皮肤病学 | 87篇 |
神经病学 | 586篇 |
特种医学 | 151篇 |
外科学 | 746篇 |
综合类 | 89篇 |
一般理论 | 9篇 |
预防医学 | 876篇 |
眼科学 | 84篇 |
药学 | 366篇 |
中国医学 | 1篇 |
肿瘤学 | 686篇 |
出版年
2024年 | 3篇 |
2023年 | 34篇 |
2022年 | 56篇 |
2021年 | 137篇 |
2020年 | 83篇 |
2019年 | 100篇 |
2018年 | 155篇 |
2017年 | 121篇 |
2016年 | 140篇 |
2015年 | 157篇 |
2014年 | 250篇 |
2013年 | 362篇 |
2012年 | 533篇 |
2011年 | 621篇 |
2010年 | 335篇 |
2009年 | 296篇 |
2008年 | 543篇 |
2007年 | 635篇 |
2006年 | 568篇 |
2005年 | 582篇 |
2004年 | 534篇 |
2003年 | 478篇 |
2002年 | 490篇 |
2001年 | 60篇 |
2000年 | 30篇 |
1999年 | 72篇 |
1998年 | 59篇 |
1997年 | 59篇 |
1996年 | 54篇 |
1995年 | 44篇 |
1994年 | 45篇 |
1993年 | 31篇 |
1992年 | 32篇 |
1991年 | 32篇 |
1990年 | 16篇 |
1989年 | 11篇 |
1988年 | 9篇 |
1987年 | 12篇 |
1986年 | 8篇 |
1985年 | 11篇 |
1984年 | 22篇 |
1983年 | 13篇 |
1982年 | 19篇 |
1981年 | 11篇 |
1980年 | 19篇 |
1979年 | 2篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1975年 | 3篇 |
排序方式: 共有7898条查询结果,搜索用时 31 毫秒
21.
Linda Klieman MSN ANP Shauna Hyde MS RD CDE Kathy Berra MSN ANP William Haskell PhD 《Current cardiovascular risk reports》2007,1(4):335-339
The benefits of regular physical activity in older persons are numerous and well established. Regular physical activity in
older adults is associated with an overall improvement in health, functional capacity, quality of life, and independence.
Many questions arise for healthcare providers regarding an older person’s ability and motivation to be physically active.
The healthcare provider has a unique opportunity to assess the older client’s incentives, preferences, and abilities for physical
activities, as well as to prescribe a safe, appropriate, and enjoyable exercise plan. The exercise precription can be simple
yet thorough enough to ensure benefits in an older person’s health and functional capacity. 相似文献
22.
Kathy Dujardin Pascal Sockeel David Devos Marie Delliaux Pierre Krystkowiak Alain Destée Luc Defebvre 《Movement disorders》2007,22(6):778-784
The objective of this study was to use the Lille Apathy Rating Scale to assess apathy in a large population of Parkinson's disease (PD) patients and identify several different apathy profiles. One hundred fifty-nine patients with probable PD and 58 healthy controls participated in the study. Apathy was assessed using the Lille Apathy Rating Scale. Motor, cognitive, and depressive symptoms were rated on standardized scales. Data were analyzed using linear regression and multivariate analyses of variance. Thirty-two percent of the PD patients were classified as apathetic. Apathy was more frequent in patients with dementia. The four apathy dimensions contributed differently to the overall severity of the apathetic condition. Action initiation and intellectual curiosity had a marked influence. Linear regression analysis revealed that the apathy level was mainly determined by cognitive impairment, not associated with the severity of motor symptoms, and only associated with the apathy subcomponent of the Montgomery and Asberg Depression Rating Scale. Apathy is highly prevalent in PD patients. Apathy profiles vary according to the clinical presentation of PD. The high prevalence of apathy in PD suggests the involvement of frontal-subcortical circuits. Although the neurochemical substrate of apathy remains poorly characterized, the strong link between apathy and cognitive impairment observed in several studies suggests the participation of nondopaminergic circuits. 相似文献
23.
Andreas Kiriakopoulos Dimitrios Tsakayannis Savas Papadopoulos Dimitrios Linos 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2005,9(3):349-351
BACKGROUND: Epidermoid splenic cysts are uncommon lesions of the spleen. They are known to become symptomatic as a consequence of enlargement, infection, or rupture, the latter being an exceedingly rare complication traditionally treated with open splenectomy. We herein report a unique case of a giant epidermoid splenic cyst that ruptured spontaneously and was successfully treated with the laparoscopic approach. CONCLUSION: Laparoscopic surgery may be considered an initial treatment option in cases of very large epidermoid cysts even when rupture occurs. 相似文献
24.
Nicholas N Nissen Jeremy Korman Thomas Kleisli Kathy E Magliato 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2005,9(4):481-484
Evaluation and management of abdominal pathology in patients with ventricular assist devices is likely to become increasingly important as the utilization of these devices expands. Ventricular assist devices represent a class of intracorporeal or paracorporeal mechanical devices that augment cardiac output in patients with congestive heart failure. Patients with ventricular assist devices supporting both right and left ventricles (biventricular assist devices) are uniquely challenging to the general surgeon because these devices restrict direct access to the abdominal cavity and because of the perioperative implications of biventricular heart failure. We describe herein the first reported successful laparoscopic cholecystectomy in a patient with a paracorporeal biventricular assist device. Cholecystectomy was performed in this patient for acute cholecystitis that occurred while the patient was awaiting heart transplantation. Our results add weight to the small body of evidence that laparoscopy is well tolerated in ventricular assist devices patients. The unique aspects of the biventricular assist device patient make laparoscopic abdominal intervention particularly suitable in this patient population. 相似文献
25.
26.
27.
28.
向珍阳 《中国医疗器械信息》2007,13(8):7-10
大多数药物注射包部件(例如针头、注射器、活塞和瓶等)都要求采用某些形式的表面处理或润滑,以便改善其操作性和功能性。本文综述了硅烷化使用的材料和工艺,以及在其后对硅烷化制品的消毒和硅油的清除。 相似文献
29.
Yifat Cohen Anthony Spirito Cheryl Sterling Deidre Donaldson Ronald Seifer Barry Plummer Ruscinda Avila Kathy Ferrer 《Journal of child psychology and psychiatry, and allied disciplines》1996,37(8):989-993
Adolescents who were psychiatrically hospitalized ( N = 105) were classified as sexually abused, physically abused, both sexually and physically abused, or not abused, and studied to determine the prevalence of suicidal behavior and psychiatric disorders. Self-reports of hopelessness, depression, coping, and self-concept were also examined. No difference in suicidal behavior or psychiatric disorder, based on abuse history, was found, with one exception. Adolescents who were sexually abused, particularly those who experienced the most severe sexual abuse, used negative coping strategies more often than those not sexually abused. Findings suggest that symptomatology of adolescents who are psychiatrically hospitalized does not differ markedly based on history of abuse. 相似文献
30.
George V Dedoussis Demosthenes B Panagiotakos Nikoleta V Vidra Eirini Louizou Christina Chrysohoou Athanasios Germanos Yannis Mantas Savas Tokmakidis Christos Pitsavos Christodoulos Stefanadis 《Genetics in medicine》2005,7(6):411-416
PURPOSE: We investigated the association of a polymorphism within the promoter of TauNuF-alpha locus at the position -308 on the likelihood of having acute coronary syndromes (ACS) in Greek adults. METHODS: We studied demographic, lifestyle, and clinical information in 237 hospitalized patients (185 males) with a first event of an ACS and 237 matched by age and sex (controls) without any clinical evidence of coronary heart disease. Genotyping was performed by PCR-RFLP analysis. RESULTS: The genotype frequencies were in patients, 87% (n = 206), 12% (n = 29), and 1% (n = 2) for G/G, G/A, and A/A, and in controls, 96% (n = 227), 4% (n = 10), and 0% (n = 0) for G/G, G/A, and A/A, respectively (P = 0.04). After adjusting for age and sex, as well as various potential confounders, we observed that G/A or A/A genotypes were associated with 1.94-fold higher odds (95% CI 1.06 to 3.68) of ACS compared to G/G homozygotes. No gene to-gender or to-clinical syndrome interactions were observed. Further subgroup analysis showed that the distribution of TNF-alpha -308G>A polymorphism was associated with the presence of family history of CHD in patients, but not in controls. In particular, in G/A and A/A patients 17.2% reported family history of CHD, whereas in G/G patients, 34.5% reported family history (P = 0.036). CONCLUSIONS: Our findings may state a hypothesis of an association between the -308G>A TNF-alpha polymorphism the development of ACS and the presence of family history of CHD, in Greece. 相似文献