The effect of cimetidine on the immediate cutaneous response to allergens.

The effects of an H2 antagonist cimetidine on the immediate cutaneous response to timothy or ragweed extract were evaluated. Cimetidine had no effect on the immediate cutaneous response to either allergen. These findings suggest that cimetidine need not be discontinued prior to allergy skin testing.     

Dynamic NMR cardiac imaging in a piglet

NMR echo-planar imaging (EPI) has been used in a realtime mode to visualise the thorax of a live piglet. Moving pictures are available on an immediate image display system which demonstrates dynamic cardiac function. Frame rates vary from one per cardiac cycle in a prospective stroboscopic mode with immediate visual output to a maximum of 10 frames per second yielding up to six looks in one piglet heart cycle, but using a visual playback mode. A completely new system has been used to obtain these images, features of which include a probe assembly with 22 cm access and an AP400 array processor for real-time data processing.