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31.
松花粉和松针提取物在亲脂性体外模型系统中抗氧化能力和机制的研究 总被引:3,自引:0,他引:3
目的:对松花粉和松针提取物在亲脂性抗氧化模型系统中的抗氧化能力和机制进行研究。方法:采用铜诱导的LDL氧化反应模型和Rose Bengal反应模型分别进行评价。结果:松花粉乙醇提取液具有较好的自由基链式反应阻断剂的作用,有效地推迟人血浆中低密度脂蛋白(LDL)氧化生成共轭二烯。松针乙醇提取液对LDL的保护作用优于松花粉。在Rose Bengal系统中,松花粉以清除自由基和螯合铜的两种机制抑制脂质过氧化反应的发生,而松针主要作为自由基清除剂发挥抗氧化作用。结论:松花粉和松针在两个亲脂性体外模型中均发挥很好的抗氧化能力,而抗氧化机制不尽相同。 相似文献
32.
Ambulatory sclerotherapy for malignant pleural effusions 总被引:12,自引:0,他引:12
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Subcellular localization of transforming growth factor-alpha in human eosinophil granulocytes 总被引:1,自引:1,他引:0
Eosinophils are involved in the inflammatory response seen in allergy and helminthic infestations. Eosinophils synthesize transforming growth factor-alpha (TGF-alpha), which may play a role in the development of the characteristic fibrosis seen in longstanding high eosinophilia. Using immunoelectron microscopic techniques, eosinophils from peripheral blood of healthy individuals and from one patient with high eosinophilia showed presence TGF-alpha in matrix of the specific crystalloid-containing granules. In cryosections, TGF-alpha was also visualized in a vesicular compartment of the cytoplasm. In double- labeling experiments, the TGF-alpha of this latter compartment did not colocalize with CD63, a marker for lysosomes, nor with albumin of secretory vesicles. In extracts from eosinophils, obtained from healthy donors, immunoreactive TGF-alpha could be detected by enzyme-linked immunosorbent assay-technique. In addition, sera from two patients with high eosinophilia showed TGF-alpha concentrations of 1.5 ng/mL and 164 pg/mL, respectively, whereas TGF-alpha could not be detected in serum from healthy controls. In conclusion, TGF-alpha is present in the specific granules, and in an additional vesicular compartment of the cytoplasm of eosinophils. 相似文献
34.
Bilateral fractures of femoral neck in patients with moderate renal failure receiving fluoride for spinal osteoporosis 总被引:3,自引:0,他引:3
J C Gerster S A Charhon P Jaeger G Boivin D Briancon A Rostan C A Baud P J Meunier 《British medical journal (Clinical research ed.)》1983,287(6394):723-725
Two patients with moderate renal failure sustained spontaneous bilateral hip fractures during treatment with fluoride, calcium, and vitamin D for osteoporosis. They had been taking sodium fluoride (40-60 mg/day) for 11 and 21 months, respectively. Histological examination of a specimen of the bone showed severe fluorosis in the first case, and quantitative analysis of bone showed osteomalacia and skeletal fluorosis in the other case. These abnormalities were considered to be the consequence of excessive retention of fluoride due to renal insufficiency. As bilateral femoral neck fractures are very rare these data suggest a causal link between fractures and fluoride in patients with renal failure. Thus fluoride should be given at a lower dosage, if at all, to patients with even mild renal failure. 相似文献
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A review of the gall-bladder content of the 193 patients that underwent a cholecystectomy at the University Hospital of Lausanne, Switzerland, in 1977, was done in order to find out the diagnostic accuracy of sonographic examination of the gall-bladder, oral cholecystography and intravenous cholangiography. Sonographic examination of the gall-bladder proofed to be accurate in 92.5% of 109 cases. We found a false negative rate of 4.5% (5 cases) and a false positive rate of 1% (1 case) as well as an indeterminate rate of 2% (2 cases). In 37% (46 cases) of the 124 patients that underwent oral cholecystography and/or intravenous cholangiography the gall-bladder was not visualized. Sonographic examination of gall-bladder is free of side effects and can be done on emergency, on jaundiced or pregnant patients, and it is enough reliable for the surgeon to make a decision to operate the gall-bladder. Low cost of the procedure is another point in favour of sonographic examination of the gall-bladder. 相似文献
37.
The authors draw up a tentative account of the physiological load a pilot bears during a Supercross event. Examination of heart frequency and blood lactate concentration curves during a series of races shows that this sport is not only highly stressful, but demands by the same token a muscular effort which has to be taken into account. Muscular work is of the mixed type, both aerobic and anaerobic, the share of the latter being of moderate importance, as it depends mainly on the technical proficiency of the driver. 相似文献
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Rostan E 《Facial Plastic Surgery Clinics of North America》2007,15(1):55-61, vi
This article reviews the currently available collagen injectable fillers and describes injection techniques. Collagen was one of the first fillers for aesthetic enhancement and has been in use for more than 20 years. In recent years there has been a surge of new injectable fillers, with more anticipated in the near future. Despite the large number of new products for augmentation and wrinkle filling, there still remains a role for injectable collagen--alone and in combination with other wrinkle fillers. 相似文献
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