全文获取类型
收费全文 | 3434篇 |
免费 | 167篇 |
国内免费 | 33篇 |
专业分类
耳鼻咽喉 | 30篇 |
儿科学 | 90篇 |
妇产科学 | 47篇 |
基础医学 | 309篇 |
口腔科学 | 22篇 |
临床医学 | 265篇 |
内科学 | 628篇 |
皮肤病学 | 44篇 |
神经病学 | 619篇 |
特种医学 | 84篇 |
外科学 | 934篇 |
综合类 | 12篇 |
预防医学 | 146篇 |
眼科学 | 25篇 |
药学 | 139篇 |
中国医学 | 5篇 |
肿瘤学 | 235篇 |
出版年
2023年 | 30篇 |
2022年 | 50篇 |
2021年 | 85篇 |
2020年 | 56篇 |
2019年 | 98篇 |
2018年 | 91篇 |
2017年 | 72篇 |
2016年 | 80篇 |
2015年 | 111篇 |
2014年 | 146篇 |
2013年 | 153篇 |
2012年 | 239篇 |
2011年 | 273篇 |
2010年 | 169篇 |
2009年 | 124篇 |
2008年 | 208篇 |
2007年 | 216篇 |
2006年 | 190篇 |
2005年 | 171篇 |
2004年 | 160篇 |
2003年 | 148篇 |
2002年 | 127篇 |
2001年 | 64篇 |
2000年 | 66篇 |
1999年 | 55篇 |
1998年 | 31篇 |
1997年 | 22篇 |
1996年 | 29篇 |
1995年 | 22篇 |
1994年 | 20篇 |
1993年 | 22篇 |
1992年 | 40篇 |
1991年 | 30篇 |
1990年 | 39篇 |
1989年 | 31篇 |
1988年 | 21篇 |
1987年 | 22篇 |
1986年 | 15篇 |
1985年 | 13篇 |
1984年 | 13篇 |
1983年 | 12篇 |
1982年 | 7篇 |
1981年 | 4篇 |
1980年 | 5篇 |
1979年 | 9篇 |
1978年 | 6篇 |
1977年 | 5篇 |
1976年 | 5篇 |
1975年 | 5篇 |
1966年 | 6篇 |
排序方式: 共有3634条查询结果,搜索用时 15 毫秒
61.
62.
63.
Howard Vernon Rocco Guerriero Shawn Kavanaugh Aaron Puhl 《The Journal of the Canadian Chiropractic Association》2015,59(3):288-293
Objectives:Modify the Tampa Scale for Kinesiophobia (TSK) for ‘fear of passive motion’ beliefs.Methods:With permission, a 14-item modification, the TSK-PM (passive movement), was created. Test-retest reliability was tested first. Construct validity was tested in chronic whiplash patients by comparing the TSK-PM with the TSK, the Neck Disability Index (NDI) and cervical ranges of motion.Results:The TSK-PM showed high test-retest reliability (r = 0.83) and high correlation with the original TSK (r = 0.84). Low, non-significant correlations were found with other variables. NDI scores were strongly correlated with ranges of motion.Conclusions:While having high test-retest reliability and a single factor structure, the TSK-PM failed to demonstrate distinctive construct validity vs the original TSK. The original TSK is likely to be sufficient to assess fear of being moved in neck pain patients in a clinical setting. Modifications to the current version of the TSK-PM might improve its construct validity in future studies. 相似文献
64.
65.
Giuseppe?SimoneEmail author Giovanni?Battista?Di?Pierro Rocco?Papalia Rosa?Sciuto Sandra?Rea Mariaconsiglia?Ferriero Salvatore?Guaglianone Carlo?Ludovico?Maini Michele?Gallucci 《World journal of urology》2015,33(10):1511-1518
Purpose
To highlight a new imaging acquisition protocol during 18F-fluorocholine PET/CT in patients with biochemical recurrence after RP.Methods
A total of 146 patients with PSA levels between 0.2 and 1 ng/ml with negative conventional imaging who did not receive salvage treatment were prospectively enrolled. Imaging acquisition protocol included an early dynamic phase (1–8 min), a conventional whole body (10–20 min), and a late phase (30–40 min). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were measured. Univariable and multivariable analyses were performed to identify independent predictors of positive PET/CT.Results
The median trigger PSA was 0.6 ng/ml (IQR 0.43–0.76). Median PSA doubling time (PSA DT) was 7.91 months (IQR 4.42–11.3); median PSA velocity (PSAV) was 0.02 ng/ml per month (IQR 0.02–0.04). Overall, 18F-fluorocholine PET/CT was positive in 111 of 146 patients (76 %). Out of 111 positive examinations, 80 (72.1 %) were positive only in the early dynamic phase. Sensitivity, specificity, PPV, NPV, and accuracy were 78.9, 76.9, 97.2, 26.3, and 78.7 %, respectively. At multivariable logistic regression, trigger PSA ≥ 0.6 ng/ml [odds ratio (OR) 3.13; p = 0.001] and PSAV ≥ 0.04 ng/ml per month (OR 4.95; p = 0.004) were independent predictors of positive PET/CT. The low NPV remains the main limitation of PET/CT in this setting of patients.Conclusions
The increased sensitivity, thanks to the early imaging acquisition protocol, makes 18F-fluorocholine PET/CT an attractive tool to detect prostate cancer recurrences in patients with a PSA level <1 ng/ml.66.
67.
Leonardo Frazzoni Franco Radaelli Cristiano Spada Alessandro Mussetto Marzio Frazzoni Liboria Laterza Emanuele Rondonotti Marina La Marca Rocco Maurizio Zagari Stefania Piccirelli Franco Bazzoli Carlo Fabbri Mauro Manno Giovanni Aragona Gianpiero Manes Pietro Occhipinti Sergio Cadoni Cesare Hassan Lorenzo Fuccio 《Digestive and liver disease》2021,53(2):224-230
BackgroundColonoscopy demands a considerable amount of resources, and little is known about its diagnostic yield among inpatients.AimsTo assess indications, diagnostic yield and findings of colonoscopy for inpatients, and to identify risk factors for relevant findings and cancer.MethodsMulticentre, prospective, observational study including 12 hospitals. Consecutive adult inpatients undergoing colonoscopy were evaluated from February through November 2019.Results1,302 inpatients underwent colonoscopy. Diagnostic yield for relevant findings and cancer was 586 (45%) and 112 (8.6%), respectively. Adequate colon cleansing was achieved in 896 (68.8%) patients. Split-dose/same-day regimen was adopted in 847 (65%) patients. Factors associated to relevant findings were age ≥70 years (RR 1.32), male gender (RR 1.11), blood loss (RR 1.22) and adequate cleansing (RR 1.63). Age ≥70 years (RR 2.08), no previous colonoscopy (RR 2.69) and split-dose/same-day regimen (RR 1.59) significantly increased cancer detection. Implementing adequate cleansing and split-dose/same-day regimen in all patients would increase the diagnostic yield for any relevant findings and cancer from 43% to 70% and from 6% to 10%, respectively.ConclusionRelevant colorectal diseases and cancer were frequent among inpatients. Factors associated with detection of relevant findings were identified. Adequate colon cleansing and split-dose/same-day regimen significantly increased colonoscopy diagnostic yield. 相似文献
68.
Federico di Rocco Geneviève Baujat Eric Arnaud Dominique Rénier Jean-Louis Laplanche Valérie Cormier Daire Corinne Collet 《European journal of human genetics : EJHG》2014,22(12):1413-1416
TCF12 mutations have been reported very recently in coronal synostosis. We report several cases of familial coronal synostosis among four families harbouring novel TCF12 mutations. We observed a broad interfamilial phenotypic spectrum with features overlapping with the Saethre–Chotzen syndrome. TCF12 molecular testing should be considered in patients with unilateral- or bilateral-coronal synostosis associated or not with syndactyly, after having excluded mutations in the TWIST1 gene and the p.Pro250Arg mutation in FGFR3. 相似文献
69.
Francesca Cannata Gianluca Vadal Luca Ambrosio Sara Fallucca Nicola Napoli Rocco Papalia Paolo Pozzilli Vincenzo Denaro 《Diabetes/metabolism research and reviews》2020,36(1)
Obesity (OB) and type 2 diabetes (T2D) are among the most prevalent metabolic diseases. They currently affect a substantial part of the world population and are characterized by several systemic co‐morbidities, including cardiovascular diseases, stroke, cancer, liver steatosis, and musculoskeletal disorders, by increasing the risk of developing osteoarthritis and intervertebral disc degeneration (IVDD). IVDD is a chronic, progressive process whose main features are disc dehydration, loss of disc height, and changes of load distribution across the spine, resulting in disc structure disruption and leading to low back pain onset. Given the high prevalence of these metabolic disorders and their association with IVDD, several studies have been conducted in order to investigate the causative role of biological and biomechanical characteristics proper to these conditions in the development of IVDD. This review aims to analyse the role of OB and T2D on IVDD, in order to clarify the pathophysiological drivers of the degenerative process and to delineate possible targets to which appropriate treatments may be addressed in the near future. 相似文献
70.
M. Fumi D. Martins Y. Pancione S. Sale V. Rocco 《International journal of laboratory hematology》2014,36(6):628-635