全文获取类型
收费全文 | 12207篇 |
免费 | 2655篇 |
国内免费 | 134篇 |
专业分类
耳鼻咽喉 | 391篇 |
儿科学 | 297篇 |
妇产科学 | 324篇 |
基础医学 | 525篇 |
口腔科学 | 170篇 |
临床医学 | 3395篇 |
内科学 | 2275篇 |
皮肤病学 | 359篇 |
神经病学 | 1004篇 |
特种医学 | 381篇 |
外科学 | 1558篇 |
综合类 | 387篇 |
现状与发展 | 2篇 |
一般理论 | 5篇 |
预防医学 | 2169篇 |
眼科学 | 139篇 |
药学 | 420篇 |
1篇 | |
中国医学 | 102篇 |
肿瘤学 | 1092篇 |
出版年
2024年 | 86篇 |
2023年 | 435篇 |
2022年 | 144篇 |
2021年 | 366篇 |
2020年 | 560篇 |
2019年 | 248篇 |
2018年 | 666篇 |
2017年 | 679篇 |
2016年 | 693篇 |
2015年 | 771篇 |
2014年 | 823篇 |
2013年 | 1222篇 |
2012年 | 650篇 |
2011年 | 606篇 |
2010年 | 654篇 |
2009年 | 746篇 |
2008年 | 536篇 |
2007年 | 451篇 |
2006年 | 484篇 |
2005年 | 393篇 |
2004年 | 338篇 |
2003年 | 302篇 |
2002年 | 257篇 |
2001年 | 199篇 |
2000年 | 120篇 |
1999年 | 164篇 |
1998年 | 297篇 |
1997年 | 311篇 |
1996年 | 325篇 |
1995年 | 258篇 |
1994年 | 181篇 |
1993年 | 124篇 |
1992年 | 90篇 |
1991年 | 93篇 |
1990年 | 80篇 |
1989年 | 98篇 |
1988年 | 72篇 |
1987年 | 59篇 |
1986年 | 57篇 |
1985年 | 57篇 |
1984年 | 52篇 |
1983年 | 45篇 |
1982年 | 34篇 |
1981年 | 47篇 |
1980年 | 23篇 |
1979年 | 11篇 |
1978年 | 13篇 |
1977年 | 17篇 |
1976年 | 13篇 |
1975年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
Antiproliferative Activity Against MCF‐7 Breast Cancer Cells by Diamino‐Triazaspirodiene Antifolates
Xiang Ma Renee Ser‐Peng Woon Paul Chi‐Lui Ho Wai‐Keung Chui 《Chemical biology & drug design》2009,74(3):322-326
Two triazaspirodienes, having similar phenoxy propyloxy side chain, were identified as potent mammalian dihydrofolate reductase inhibitors; one having a 6,5‐spiro bicyclic ring system (IC50 = 2.3 nm ) and the other a 6,6‐spiro bicyclic system (IC50 = 6.9 nm ). They also showed more than 50% antiproliferative activity against the MCF‐7 breast cancer cells at 20 μm . This study demonstrated the potential lead of the diamino‐triazaspirodienes in anticancer chemotherapeutical agents’ discovery. 相似文献
32.
Neuropsychological assessment, neuroimaging, and neuropsychiatric evaluation in pediatric and adult patients with sickle cell disease (SCD)
下载免费PDF全文
![点击此处可从《Neuropsychiatric Disease and Treatment》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Christopher L Edwards Renee Dunn Raynor Miriam Feliu Camela McDougald Stephanie Johnson Donald Schmechel Mary Wood Gary G Bennett Patrick Saurona Melanie Bonner Chante Wellington Laura M DeCastro Elaine Whitworth Mary Abrams Patrick Logue Lekisha Edwards Salutario Martinez Keith E Whitfield 《Neuropsychiatric Disease and Treatment》2007,3(6):705-709
Traditionally, neuropsychological deficits due to Sickle Cell Disease (SCD) have been understudied in adults. We have begun to suspect, however, that symptomatic and asymptomatic Cerebrovascular Events (CVE) may account for an alarming number of deficits in this population. In the current brief review, we critically evaluated the pediatric and adult literatures on the neurocognitive effects of SCD. We highlighted the studies that have been published on this topic and posit that early detection of CVE via neurocognitive testing, neuropsychiatric evaluations, and neuroimaging may significantly reduce adult cognitive and functional morbidities. 相似文献
33.
34.
35.
36.
Rufus S. HoweCPT AN BSE BSN RN-C Claudia ChrlstmanCPT AN MS BA BSN RN-C 《Journal of the American Academy of Nurse Practitioners》1991,3(1):35-41
Noninsulin dependent diabetes (type II diabetes) is a chronic disease characterized by hyperglycemia. Clients can generally be controlled by diet and exercise or a combination of diet, exercise, and oral hypoglycemic agents. When this therapy is not effective in controlling the hyperglycemia, the health care provider must choose to initiate insulin therapy. Outpatient initiation of insulin is an alternative to hospitalization in the type II diabetic client. Clinical guidelines for the initiation of insulin on an outpatient basis and management of the diabetic client are presented. 相似文献
37.
The current study evaluated psychosocial variables that may contribute to the experience of headache in college adults. One hundred ninety-nine participants, 103 women and 96 men, completed head pain logs for 4 weeks after completing measures assessing psychosocial variables. Multiple regression analyses indicated that level of emotional functioning, perception of stress, and gender were predictive of future headache frequency, intensity, and duration. Family history and health habits did not predict headache activity. These findings are consistent with research investigating psychosocial variables and headache activity. 相似文献
38.
Karen A Luker PhD BNurs RGN RHV NDNCert Kinta Beaver BA RGN DPSN Samuel J Leinster BSc MD FRCS R Glynn Owens BTech DipPsych DPhil AFBPsS Lesley F Degner PhD RN Jeffrey A Sloan PhD BSc 《Journal of advanced nursing》1995,22(1):134-141
Nurses can play a key role in patient education, including providing patients with useful and approrate information Rather than focusing on the process of education or information giving by nurses, this study places emphasis on the content of that information by taking the patients'perspective and asking the patients themselves what particular types of information are perceived as important at a specific point in time The aim of the study was to explore what particular types of information were important to women newly diagnosed with breast cancer, to enable nurses and other health care professionals to utilize their time as effectively as possible and provide a high-quality service to individuals in their care Women with breast cancer (a mean of 2 5 weeks from diagnosis) were interviewed and asked to compare items of information The items of information were presented m pairs and the women stated a preference for one item in that pan- Thirty-six pairs were presented in total The analysis involved the use of a Thurstone scaling model, which allowed rank ordermgs, or profiles of information needs, to be developed, reflecting the perceived importance of each item Information about the likelihood of cure, the spread of the disease and treatment options were perceived as the most important items of information at the tune of diagnosis Other information needs, in order of descending priority, included information about the risk to family, side-effects 相似文献
39.
A comparison of the stressors experienced by parents of intubated and non-intubated children 总被引:3,自引:0,他引:3
Caroline Haines BN RGN RSCN Christine Perger BHSc Sue Nagy RN BA FRCNA FCN 《Journal of advanced nursing》1995,21(2):350-355
When children are ill enough to require admission to paediatric intensive care, parents may become distressed about their child's medical condition and this distress may be compounded by the unfamiliar nature of the highly technological environment Parents of children who are sick enough to warrant intubation are particularly likely to be exposed to a frightening array of technological equipment Seventy-one parents of intubated and non-intubated children completed the Parental Stressor Scale Paediatnc Intensive Care Unit (PSS PICU) Overall the findings suggest that parents were most distressed (a) by the painful procedures to which their children were subjected, (b) by the sights and sounds of the intensive care unit and (c) by their children's reactions to intensive care The behaviour of staff towards parents and the way that staff communicated with them caused the least distress When the levels of stress reported by parents of intubated children were compared with those reported by parents of non-intubated children, different patterns of stress were found Painful procedures were a source of greater stress to parents of intubated children whereas the behaviour of staff and the children's reactions to the intensive care experience caused greater stress to the parents of the non-intubated children In general the findings suggest that the needs of parents of non-intubated children are being overlooked, with staff focusing more of their attention on the parents of intubated children 相似文献
40.
M J Ahern MD FRACP M Wetherall BEd A Leslie MB BS R H James BSc P J Roberts-Thomson PhD FRACP G C Rennie BA BSc MA 《International journal of clinical practice》1992,46(4):229-233
The elderly (age >65 years) are more vulnerable to side-effects induced by non-steroidal anti-inflammatory drugs (NSAIDs). We therefore performed a double-blind comparative study of ketoprofen SR and sulindac in patients with active rheumatoid arthritis, 65 years of age or older. Sulindac was chosen because of its possible renal sparing effects, and ketoprofen SR because of its short half life and sustained release delivery system. Eighty patients were entered. More patients withdrew from the study due to side-effects in the sulindac group; both treatment groups had a high incidence of side-effects during this study and during previous exposure to other NSAIDs, demonstrating that the elderly are susceptible to side-effects from NSAIDs. 相似文献