全文获取类型
收费全文 | 197219篇 |
免费 | 2524篇 |
国内免费 | 83篇 |
专业分类
耳鼻咽喉 | 1336篇 |
儿科学 | 7305篇 |
妇产科学 | 3612篇 |
基础医学 | 19798篇 |
口腔科学 | 2425篇 |
临床医学 | 14673篇 |
内科学 | 35087篇 |
皮肤病学 | 1109篇 |
神经病学 | 18591篇 |
特种医学 | 9532篇 |
外科学 | 30688篇 |
综合类 | 2487篇 |
现状与发展 | 1篇 |
一般理论 | 23篇 |
预防医学 | 20418篇 |
眼科学 | 3068篇 |
药学 | 11156篇 |
中国医学 | 704篇 |
肿瘤学 | 17813篇 |
出版年
2024年 | 32篇 |
2023年 | 289篇 |
2022年 | 521篇 |
2021年 | 904篇 |
2020年 | 626篇 |
2019年 | 931篇 |
2018年 | 22682篇 |
2017年 | 17948篇 |
2016年 | 20109篇 |
2015年 | 1698篇 |
2014年 | 1811篇 |
2013年 | 2071篇 |
2012年 | 8923篇 |
2011年 | 22896篇 |
2010年 | 19742篇 |
2009年 | 12422篇 |
2008年 | 20871篇 |
2007年 | 23102篇 |
2006年 | 1804篇 |
2005年 | 3455篇 |
2004年 | 4475篇 |
2003年 | 5247篇 |
2002年 | 3331篇 |
2001年 | 393篇 |
2000年 | 464篇 |
1999年 | 268篇 |
1998年 | 330篇 |
1997年 | 337篇 |
1996年 | 171篇 |
1995年 | 178篇 |
1994年 | 163篇 |
1993年 | 123篇 |
1992年 | 82篇 |
1991年 | 120篇 |
1990年 | 158篇 |
1989年 | 103篇 |
1988年 | 90篇 |
1987年 | 77篇 |
1986年 | 58篇 |
1985年 | 58篇 |
1984年 | 38篇 |
1983年 | 41篇 |
1982年 | 53篇 |
1980年 | 51篇 |
1974年 | 25篇 |
1938年 | 60篇 |
1937年 | 27篇 |
1934年 | 30篇 |
1932年 | 57篇 |
1930年 | 48篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Background
The fibromyalgia syndrome (FMS) is suggested to be a manifestation of depression or affective spectrum disorder. We measured the cognitive style of patients with FMS to assess personality styles in 44 patients with fibromyalgia syndrome (FMS) by comparing them with 43 patients with major depressive disorder (MDD) and 41 healthy controls (HC). 相似文献42.
43.
44.
Introduction Choroid plexus cysts can lead to isolation of the lateral ventricles and distension of the third ventricle. We present an
ultrasonographic video documentation of an infant with variably shaped and localized choroid plexus cyst of the third ventricle.
Case report An infant had periods of increased intracranial pressure with changing dilatation of the first to third ventricle. Cerebral
ultrasonography of the not crying boy demonstrated a choroid plexus cyst limply hanging down from the roof of the third ventricle
to the beginning of the aqueduct of Sylvius. During crying, the cyst prolapsed from the third into left lateral ventricle
and was strangled by the foramen of Monro. Endoscopic cyst fenestration and third ventriculostomy continuously solved the
problem of intermittent hydrocephalus occlusus.
Conclusion Depending not only on localization and size but also on cyst form and cerebrospinal fluid pressure, a single choroid plexus
cyst can cause various obstructions of cerebrospinal fluid pathways. 相似文献
45.
Murat Hamit Aytar Fikret Doğulu Berker Cemil Ertan Ergün Gökhan Kurt Kemali Baykaner 《Child's nervous system》2007,23(6):719-721
Introduction Iniencephaly, a neural tube defect involving occiput and inion and combined with rachischisis of the cervical, thoracic spine,
and retroflexion position of the head is a very rare congenital abnormality of the fetus–newborn with a 0.1–10 of 10,000 prevalence.
This abnormality’s prognosis is thought to be dismal. This abnormality can be associated with other abnormalities such as
anencephaly, encephalocele, hydrocephalus, cyclopia, absence of the mandible, cleft lip and palate, cardiovascular disorders,
diaphragmatic hernia, renal abnormalities, overgrowth of the arms compared to the legs, and club food and gastrointestinal
atresia.
Discussion Most of the patients are dead born, and the others die in a few hours. There are only six previously documented long-term
survivors. In our case, our patient with iniencephalic signs and findings is still living. She is 2 years old now. We think
that this patient presents a mild form of iniencephaly. 相似文献
46.
Stefan Ockert Hardy Schumacher Dittmar Böckler Katrin Malcherek Jochen Hansmann Jens Allenberg 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2007,392(6):725-730
Background and aims Since the introduction of endovascular aortic aneurysm repair (EVAR) for aortic aneurysms, the number of juxtarenal aortic
aneurysms (JRA) has been growing steadily due to selection bias (neck morphology for EVAR). This case-match study compares
the perioperative outcome and midterm results of suprarenally clamped JRA with infrarenal aortic aneurysms (AAA).
Methods From 1997 to 2004, patients who received open surgery with suprarenal clamping for JRA were included in the study and compared
to matched patients with infrarenal clamping (AAA). Measurements analyzed were the in-hospital mortality and morbidity. Midterm
results were obtained through clinical investigation and magnetic resonance angiography imaging.
Results Thirty-five patients (mean age, 68.4 years; 30 male and 5 female) received suprarenal cross-clamping for JRA. The overall
in-hospital mortality for JRA and for the controls (AAA) with elective aortic repair was 4.5% (6.1% JRA; 3% AAA, p = 0.058). The morbidity of JRA was elevated according to the rate of pulmonary complications (p = 0.021) and the need for re-operation (p = 0.019). The mean follow-up time was 2.3 years (range, 8–96 months). At follow-up, 28 patients (80%) from the JRA group
and 29 patients from the AAA group (82.9%) were alive.
Conclusion Open aortic surgery for JRA with the need for suprarenal cross-clamping shows a slightly elevated in-hospital mortality rate
without statistical significance and equal midterm mortality results in comparison with infrarenally clamped aortic aneurysms. 相似文献
47.
Stefano Di Domenico Giulio Bovio Maximiliano Gelli Ferruccio Ravazzoni Enzo Andorno Damiano Cottalasso Umberto Valente 《BMC surgery》2007,7(1):18
Background
Liver transplantation in presence of diffuse portal vein thrombosis is possible by using caval blood as portal inflow, through cavo-portal transposition. However, clinical results are heterogeneous and experimental studies are needed, but similar hemodynamic conditions are difficult to obtain, especially in small animals. Herein we describe a new simple model of cavo-portal transposition in rat. 相似文献48.
Background
Health service policy in the United Kingdom emphasises the importance of self-care by patients with chronic conditions. Written information for patients about their condition is seen as an important aid to help patients look after themselves. From a discourse analysis perspective written texts such as patient information leaflets do not simply describe the reality of a medical condition and its management but by drawing on some sorts of knowledge and evidence rather than others help construct the reality of that condition. This study explored patient information leaflets on osteoarthritis (OA) to see how OA was constructed and to consider the implications for self-care. 相似文献49.
Javairiah Fatima Scott G. Houghton Michael G. Sarr 《Journal of gastrointestinal surgery》2007,11(8):1052-1056
Small bowel transplantation (SBT) is associated with poorly understood enteric dysfunction. The study of SBT in mice is hindered
by the technical difficulty of orthotopic SBT in the mouse. Our aim was to develop an easy preparation of extrinsic denervation
of the entire jejunoileum in mice as a model of orthotopic SBT. All neurolymphatic tissues accompanying the superior mesenteric
artery (SMA) and vein (SMV) were ligated just distal to the middle colic vessels. The SMA and SMV were then stripped of investing
adventitia, and the mesentery to jejunum and colon were transected radially. Jejunum and colon were not transected and reanastomosed.
To confirm extrinsic denervation 1, 3, and 6 months later, segments of small bowel were stained for protein gene product 9.5
(PGP9.5) and tyrosine hydroxylase (TH). Tyrosine hydroxylase immunoreactive intensity was then quantified using a semiquantitative
analysis. Immunohistochemical fluorescence showed persistence of PGP9.5 immunoreactivity confirming enteric nerves in jejunoileum;
however, there was no TH immunoreactivity in jejunoileum in denervated mice despite the expected preservation of TH immunoreactivity
in the still-innervated duodenum at 1 month. At 3 months, sparse immunoreactivity for TH was present, and by 6 months, reinnervation
of TH-containing nerves appeared similar to controls. Quantification of intensity at each time-point further confirmed this
trend. This technique in the mouse accomplishes a complete extrinsic denervation of jejunoileum early postoperatively (1 and
3 months); reinnervation occurs by 6 months. This is an easily learned murine model of orthotopic SBT.
Presented at the American Gastroenterological Association during Digestive Disease Week in Los Angeles, CA, as a poster presentation
on May 23 2006. Abstract published in GastroenterologyE 2006; 130:A604. 相似文献
50.
Treatment strategy for synchronous metastases of colorectal cancer: is hepatic resection after an observation interval appropriate? 总被引:1,自引:1,他引:0
Yasuhiro Shimizu Kenzo Yasui Tsuyoshi Sano Takashi Hirai Yukihide Kanemitsu Koji Komori Tomoyuki Kato 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2007,392(5):535-538
Background In cases of synchronous colorectal hepatic metastases, the primary colorectal cancer strongly influences on the metastases.
Our treatment policy has been to conduct hepatic resection for the metastases at an interval of 3 months after colorectal
resection. We examined the appropriateness of interval hepatic resection for synchronous hepatic metastasis.
Materials and methods The subjects were 164 patients who underwent resection of hepatic metastasis of colorectal cancer (synchronous, 70 patients;
metachronous, 94 patients). Background factors for hepatic metastasis and postoperative results were compared for synchronous
and metachronous cases.
Results The cumulative survival rate for 164 patients at 3, 5, and 10 years postoperatively was 71.9%, 51.8%, and 36.6%, and the post-resection
recurrence rate in remnant livers was 26.8%. Interval resection for synchronous hepatic metastases was conducted in 49 cases
after a mean interval of 131 days. No difference was seen in postoperative outcome between synchronous and metachronous cases.
Conclusion The outcome was similarly favorable in cases of synchronous hepatic metastasis and in cases of metachronous metastasis. Delaying
resection allows accurate understanding of the number and location of hepatic metastases, and is beneficial in determining
candidates for surgery and in selecting surgical procedure. 相似文献