全文获取类型
收费全文 | 73262篇 |
免费 | 5451篇 |
国内免费 | 368篇 |
专业分类
耳鼻咽喉 | 747篇 |
儿科学 | 1922篇 |
妇产科学 | 1817篇 |
基础医学 | 9343篇 |
口腔科学 | 1740篇 |
临床医学 | 7355篇 |
内科学 | 16403篇 |
皮肤病学 | 937篇 |
神经病学 | 5853篇 |
特种医学 | 2135篇 |
外国民族医学 | 2篇 |
外科学 | 10902篇 |
综合类 | 1284篇 |
现状与发展 | 1篇 |
一般理论 | 112篇 |
预防医学 | 6345篇 |
眼科学 | 2050篇 |
药学 | 5340篇 |
中国医学 | 167篇 |
肿瘤学 | 4626篇 |
出版年
2023年 | 333篇 |
2022年 | 568篇 |
2021年 | 1353篇 |
2020年 | 831篇 |
2019年 | 1152篇 |
2018年 | 1413篇 |
2017年 | 973篇 |
2016年 | 1138篇 |
2015年 | 1314篇 |
2014年 | 1976篇 |
2013年 | 3236篇 |
2012年 | 4360篇 |
2011年 | 4738篇 |
2010年 | 2682篇 |
2009年 | 2503篇 |
2008年 | 4535篇 |
2007年 | 4751篇 |
2006年 | 4563篇 |
2005年 | 4639篇 |
2004年 | 4343篇 |
2003年 | 3931篇 |
2002年 | 3920篇 |
2001年 | 987篇 |
2000年 | 825篇 |
1999年 | 928篇 |
1998年 | 841篇 |
1997年 | 723篇 |
1996年 | 603篇 |
1995年 | 582篇 |
1994年 | 539篇 |
1993年 | 507篇 |
1992年 | 691篇 |
1991年 | 648篇 |
1990年 | 539篇 |
1989年 | 547篇 |
1988年 | 520篇 |
1987年 | 497篇 |
1986年 | 466篇 |
1985年 | 519篇 |
1984年 | 527篇 |
1983年 | 485篇 |
1982年 | 603篇 |
1981年 | 528篇 |
1980年 | 556篇 |
1979年 | 376篇 |
1978年 | 380篇 |
1977年 | 373篇 |
1976年 | 322篇 |
1975年 | 334篇 |
1974年 | 308篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
42.
43.
A 37-year-old male with history of alcohol abuse presented to us with nausea, vomiting, and abdominal pain with ascites. He was diagnosed with alcoholic liver disease with coagulopathy and pancreatitis. During hospitalization, the patient developed intra-abdominal hemorrhage. He was treated with platelets, packed red blood cells and fresh frozen plasma without any improvement. Following this he was treated with activated recombinant factor VII (90 microg/kg), which resulted in normalization of the prothrombin time and the activated partial thromboplastin time and stabilization of hematocrit within a few hours. We review the current literature on the approved and off-label use of activated recombinant factor VII. 相似文献
44.
45.
Basil D'Souza George Dimitroulis 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(4):e59-e61
This is a case study of a patient with recurrent synovial chondromatosis. It shows some relevant images. It also provides possibilities for why this patient may have had a recurrence and how this was managed. 相似文献
46.
George A Kaysen 《Journal of renal nutrition》2007,17(1):4-8
Cardiovascular risk increases with each decrement in renal function. Low-density lipoprotein (LDL) cholesterol levels are not associated with increased mortality, but high-density lipoprotein (HDL) levels are inversely associated with cardiovascular risk. Lipoprotein composition with increased abundance of small dense LDL and HDL and reduced levels of more buoyant isoforms is similar to what is found in states of insulin resistance and in the metabolic syndrome (MS). In both cases, high triglyceride levels are associated with reduced HDL levels. Chronic kidney disease (CKD) is itself associated with increasing insulin resistance as renal function fails. In both instances, decreased levels of apo A-I and apo A-II are a consequence of increased fractional catabolic rate (FCR), resulting from a predominance of small HDL particles. HDL maturation is impaired in CKD through decreased activity of lecithin:cholesterol acyltransferase (LCAT), and increased cholesterol ester transfer protein (CETP) activity in MS shuttles triglycerides back into HDL, thereby destabilizing it. Whether insulin resistance is entirely responsible for disorders of HDL metabolism in CKD, or whether the process is a result of unrelated pathophysiology, is currently unknown. 相似文献
47.
Anil K Jain Ravindra S Chauhan Ish K Dhammi Aditya V Maheshwari Ruma Ray 《The spine journal》2007,7(2):249-253
BACKGROUND CONTEXT: Pseudoaneurysm of the aorta in association with vertebral tuberculosis is a rare phenomenon. With the resurgence of human immunodeficiency virus (HIV) and associated resistant tuberculosis, this life-threatening complication requires greater awareness. PURPOSE: Our purpose is to report the rare presentation and successful management of tubercular pseudoaneurysm of the aorta in association with vertebral tuberculosis, and to highlight the clinicoradiological features for early and prompt diagnosis of this potentially fatal, but treatable, disease. STUDY DESIGN: A single case report and overview of the disease comprises the design of this study. PATIENT SAMPLE: The patient, already surgically intervened, is a 27-year-old male with increasing abdominal and back pain, upper motor neuron signs, and constitutional signs and symptoms. OUTCOME MEASURES: At 33 months follow-up, there is complete resolution of the signs and symptoms, and the patient is back to his previous vocation. METHODS: The diagnosis was confirmed by magnetic resonance imaging and contrast computed tomography. Endoaneurysmorrhaphy of the pseudoaneurysm along with a complete course of antitubercular treatment was given to the patient, and he has presently been followed up for 33 months. RESULTS: The patient's signs and symptoms have been completely resolved without any recurrence. CONCLUSION: Despite the use of modern chemotherapy and imaging techniques, this disastrous complication still occurs and reinforces the need for early suspicion, diagnosis, surgical resection, and antitubercular therapy along with close postoperative follow-up to prevent recurrence. With the resurgence of HIV (and other immunocompromised states) associated and resistant tuberculosis, we should be more alert than ever to this life-threatening complication. 相似文献
48.
Decreased caloric intake in normal-weight patients with bulimia: comparison with female volunteers 总被引:1,自引:0,他引:1
H E Gwirtsman W H Kaye E Obarzanek D T George D C Jimerson M H Ebert 《The American journal of clinical nutrition》1989,49(1):86-92
Patients with bulimia (binge-purge syndrome) frequently complain that they consume a very restrictive diet to avoid gaining weight. To investigate this claim, 23 hospitalized bulimic patients were assessed daily for body weight, caloric intake, macronutrient diet content, activity measures, and body composition estimates during weight-stable periods. Bulimic patients ate fewer kilocalories per kilogram body weight (22.1 +/- 4.6 kcal/kg) than did age-matched normal women (29.7 +/- 6.5 kcal/kg) but had similar activity levels and body composition. Clinical variables, such as history of laxative abuse, anorexia, or obesity, and physiological characteristics, such as body weight, activity level, or dietary content, could not account for this difference in caloric consumption. Bulimic patients tended to eat a diet lower in fat and higher in protein than did control subjects. These results agree with observations of increased efficiency of caloric utilization in obese patients and support patient complaints of a tendency to gain weight easily. 相似文献
49.
50.
Stimulation by mitogens and neuronal membranes of lymphocytes from patients with motor neurone disease 总被引:1,自引:0,他引:1
Jaqueline Aspin Roger Harrison Ahmed Jehanli George Lunt Malcolm Campbell 《Journal of neuroimmunology》1986,11(1):31-40
Stimulation of lymphocytes from motor neurone disease patients by either concanavalin A or PHA was shown to be significantly depressed relative to that from normal controls, as assayed by incorporation of [3H]thymidine or [3H]leucine or by glucose uptake. Corresponding significant differences were not shown by assays based upon incorporation of [3H]uridine or of lactate release. Lymphocytes from 4 out of 14 motor neurone disease patients showed a blastogenic response to membranes from rat spinal cord cells, compared with those from 0 out of 9 normal controls. These results not only suggest the possibility of an impaired cellular immune control in MND patients but also indicate the presence of lymphocytes sensitised specifically to neuronal membrane components. 相似文献