全文获取类型
收费全文 | 35584篇 |
免费 | 1997篇 |
国内免费 | 95篇 |
专业分类
耳鼻咽喉 | 397篇 |
儿科学 | 1244篇 |
妇产科学 | 989篇 |
基础医学 | 4966篇 |
口腔科学 | 932篇 |
临床医学 | 3332篇 |
内科学 | 7446篇 |
皮肤病学 | 719篇 |
神经病学 | 3464篇 |
特种医学 | 1121篇 |
外科学 | 4505篇 |
综合类 | 173篇 |
现状与发展 | 1篇 |
一般理论 | 12篇 |
预防医学 | 2883篇 |
眼科学 | 883篇 |
药学 | 2513篇 |
中国医学 | 104篇 |
肿瘤学 | 1992篇 |
出版年
2023年 | 289篇 |
2022年 | 313篇 |
2021年 | 877篇 |
2020年 | 528篇 |
2019年 | 757篇 |
2018年 | 1126篇 |
2017年 | 851篇 |
2016年 | 883篇 |
2015年 | 883篇 |
2014年 | 1108篇 |
2013年 | 1659篇 |
2012年 | 2531篇 |
2011年 | 2581篇 |
2010年 | 1302篇 |
2009年 | 1104篇 |
2008年 | 2110篇 |
2007年 | 2219篇 |
2006年 | 2163篇 |
2005年 | 2144篇 |
2004年 | 1947篇 |
2003年 | 1939篇 |
2002年 | 1811篇 |
2001年 | 729篇 |
2000年 | 770篇 |
1999年 | 604篇 |
1998年 | 223篇 |
1997年 | 176篇 |
1996年 | 163篇 |
1995年 | 155篇 |
1994年 | 149篇 |
1993年 | 116篇 |
1992年 | 299篇 |
1991年 | 269篇 |
1990年 | 225篇 |
1989年 | 250篇 |
1988年 | 182篇 |
1987年 | 217篇 |
1986年 | 190篇 |
1985年 | 185篇 |
1984年 | 130篇 |
1983年 | 108篇 |
1982年 | 85篇 |
1981年 | 71篇 |
1979年 | 116篇 |
1978年 | 76篇 |
1977年 | 89篇 |
1975年 | 80篇 |
1974年 | 84篇 |
1973年 | 67篇 |
1972年 | 62篇 |
排序方式: 共有10000条查询结果,搜索用时 156 毫秒
121.
Iatrogenic injuries to ureter, bladder and urethra during abdominal and pelvic operations 总被引:1,自引:0,他引:1
Ö Polat O. Gül Y. Aksoy I. Özbey A. Demirel Y. Bayraktar 《International urology and nephrology》1997,29(1):13-18
Abdominal and pelvic operations at Departments of Obstetrics and Gynaecology, and General Surgery play an important role in
ureteral, bladder and rarely urethral injuries.
Fifty-nine patients with iatrogenic ureteral, bladder and urethral injuries were treated at the Department of Urology, Atatürk
University Research Hospital, between 1985 and 1995. These injuries were urinary vaginal fistulas in 43 patients (vesicovaginal
33, ureterovaginal 7, urethrovaginal 2 and vesicovaginal plus urethrovaginal 1), ureteric ligation in 9, bladder laceration
in 7. These injuries were treated by different methods. All patients were followed up by intravenous urography (IVU) and urine
culture three months later.
It must be borne in mind that iatrogenic urinary tract injuries are not rare. Bladder and ureteral catheterization must be
performed to prevent these complications. 相似文献
122.
Lundin Pål D. P. Lundin Stefan Olsson Håkan Karlsson Börje W. Weström Björn R. Pierzynowski Stefan G. 《Pharmaceutical research》1995,12(10):1478-1482
Purpose. The present investigation was done to study the intestinal absorption of three oxytocin peptide analogues and to elucidate the role of pancreatic juice on their absorption.
Methods. In conscious chronically catheterized pigs (6–8 weeks of age) plasma concentration of the peptides, [Mpa1, D-Tyr(Ethyl)2, Thr4, Orn8]-oxytocin (F314), [Mpa1, D-Tyr(Ethyl)2, Val4, D-Arg8]-oxytocin (CAT), and [Mpa1, D-Tyr(Ethyl)2, Thr4, Orn8, desGly9, carba6]-oxytocin (F327) after intraduodenal administration, during presence or diversion of the pancreatic juice via a pancreatic duct catheter, were determined by radioimmunoassay. The stability of the peptides to degradation was determined in vitro by incubation with activated pancreatic juice, chymotrypsin or trypsin, followed by reversed phase HPLC analyses.
Results. All peptides were absorbed with a bioavailability of about 0.5% in the presence of pancreatic juice, but increased to 1.0%, 2.1%, and 13.5% for F314, CAT, and F327, respectively, when the pancreatic juice was diverted from the intestine. After incubation with pancreatic juice 95% of F314, 98% of F327, and 100% of CAT was found intact. When incubated with trypsin CAT remained intact while F314 and F327 were degraded by 54% and 46%, respectively. Incubation with purified chymotrypsin did not degrade the test peptides.
Conclusions. The results indicate that the increased absorption of peptides observed under conditions of diverted pancreatic juice cannot only be explained by the absence of pancreatic enzymes, but also by changed absorptive properties in the gastrointestinal tract. 相似文献
123.
T. V. Peker C. Pelin H. B. Turgut A. Anıl A. Sevim 《European archives of oto-rhino-laryngology》1998,255(8):391-395
Since it covers the lateral wall of the mastoid air system, the suprameatal triangle is of importance to otologic surgeons
during mastoidectomy. Because of this clinical importance, topographic anatomy of the suprameatal spine and depression was
studied on Anatolian skulls. In all, 363 male and 231 female skulls were studied. The most prevalent type of suprameatal spine
resembled a crest and was found in both sexes on the right (77.6%) and left (80%) sides. The absence of a suprameatal depression
was significantly higher in females (right 9.1%; left 8.7%) than in males (right 1.7%; left 2.5%). Suprameatal depressions
were mostly shallow in female subjects, but were mostly observed in males to be at a medium depth or deep.
Received: 5 January 1998 / Accepted: 19 March 1998 相似文献
124.
Kaija Mikkola Elena Kushnerenko Eino Partanen Silve Serenius-Sirve Jaana Leip?l? Minna Huotilainen Vineta Fellman 《Clinical neurophysiology》2007,118(7):1494-1502
OBJECTIVE: In our previous study, auditory event-related potentials (AERPs) in preterm 1-year-old children had a positive deflection at 150-350 ms that correlated positively with their 2-year neurodevelopmental outcome. In a study of the same subjects at age 5, our aim was to assess AERPs and their relationship to neuropsychological test results. METHODS: Preterm small (SGA, n=13), appropriate for gestational age (AGA, n=15), and control (n=13) children were assessed with an Easy paradigm presenting a large frequency change accompanied with occasional novel sounds, and a Challenging paradigm presenting small frequency and duration changes with a rapid rate. The preterm children underwent neurocognitive tests. RESULTS: Easy paradigm. The P1 response to frequency deviant was smaller and MMN larger in the preterm than in the control children. Challenging paradigm. The P1 response to standard, frequency, and duration deviants was smaller in the preterm than in the control children. The N2 response to frequency deviant was larger in the preterm than in the control children. AGA and SGA children had similar AERPs. The P1, N2, and MMN amplitudes correlated with verbal IQ and NEPSY language subtests. CONCLUSIONS: Small P1 response(s) appears to be typical for preterm children. SIGNIFICANCE: Small P1 response in preterm children may suggest altered primary auditory processing. 相似文献
125.
Cassandra A Slader l Helen K Reddel Sinthia Z Bosnic-Anticevich 《The Journal of asthma》2004,41(3):367-373
BACKGROUND: Chlorofluorocarbon (CFC)-free metered-dose inhalers (MDIs) were introduced into Australia in 1999. Device care instructions were modified (e.g., CFC-free salbutamol inhalers to be washed weekly), but this information was not communicated directly to health care professionals. OBJECTIVE: This pilot study aimed to assess the level of awareness of device care protocols for CFC-free MDIs by patients and their pharmacists. SETTING AND DESIGN: Purchasers of CFC-free MDIs were recruited from four community pharmacies. They were interviewed regarding information sources, knowledge of propellant change, and awareness of and adherence to device care protocols. The dispensing pharmacists were interviewed for knowledge of CFC-free device care. The primary outcome variable was awareness of the relevant device care protocol. RESULTS: Thirty-nine patients were interviewed. Most patients (77%) were aware of the change to CFC-free propellant. Only nine patients (23%) were aware of the need to wash the device holder, and four patients (10% of total) complied with the specified protocol. One of the ten dispensing pharmacists could describe correct device care protocols for the CFC-free MDIs. CONCLUSIONS: Although most patients are aware that MDIs are now CFC-free, there is a low level of awareness of the device care required for these inhalers, and a very low rate of compliance with recommended practice. Although the clinical impact of failing to wash the device holder is unclear, this added instruction may have substantial implications for patient satisfaction and medication delivery. Pharmaceutical manufacturers need to highlight to health care professionals any clinically important changes in device care instructions, so that appropriate information may be passed on to patients. 相似文献
126.
127.
Does the nature of the solvent affect the anti-inflammatory capacity of triclosan? An experimental study 总被引:4,自引:0,他引:4
Anne B. Skaare Vibeke Kjærheim Pål Barkvoll Gunnar Rölla 《Journal of clinical periodontology》1997,24(2):124-128
Abstract The anti-inflammatory properties of triclosan have been revealed in several recent studies, including an effect on histamine-induced inflammation. In other studies, the nature of the solvent has been shown to be of importance for the plaque inhibiting as well as the antibacterial potential of triclosan. This study was aimed at examining whether the nature of the solvent also may influence the anti-inflammatory capacity of triclosan and further to study a possible dose/response relationship. The study was performed as 3 separate, double-blind experiments, comprising 10, 11 and 12 healthy females. In all 3 experiments, 5 sites on the lower part of the back of the volunteers were intradermally exposed to one drop of 1% histamine dihydrochloride for 15 min. The size of the resulting wheals was recorded before and after 40 min of triclosan treatment. In experiment I. 4 different concentrations of triclosan in 2-fold dilutions in absolute alcohol (0.125%-1%) were applied on the histamine-induced wheals. In experiments 2 and 3, 4 different solutions containing 0.5% triclosan and a saline solution as negative control were used. The solvents in experiment 2 were as follows: (1) absolute alcohol (positive control). (2) propylene glycol (PG), (3) polyethylene glycol (PEG). (4) olive oil, and in experiment 3: (1) absolute alcohol (positive control). (2) Tween 80. (3) sodium carbonate, (4) soy oil. The results showed a dose/ response effect of triclosan and further that the solvent may be of importance for its anti-inflammatory potential. 相似文献
128.
129.
Psychopathological reactions to fatherhood are probably not so infrequent as they would seem from psychiatric literature. In a material of paranoid psychoses, impending or newly established fatherhood was considered the main precipitating factor in 4 patients (i.e. 2.4%), compared with 7% of the female psychoses precipitated by pregnancy, childbirth or nursing. Two of the men were bachelors, insecure and inhibited, feeling compromised or helpless in the new situation. Two men were married, passive, avoidant in their personality, strongly dependent on their wives. The course and outcome varied according to the diagnoses; 2 cases having a favorable and 2 an unfavorable course and outcome. Physicians, including psychiatrists, should bear in mind that fatherhood is a possible precipitating factor for paranoid psychoses in male patients. 相似文献
130.
Pregnancies in which fetal cardiac arrhythmias are present are associated with an elevated perinatal and neonatal mortality. In this group various major and minor fetal malformations, including heart malformations, are more common. FECG and phonocardiogram give some information on the type of arrhythmia in favorable cases. Real-time imaging detects fetal heart malformations and late signs of heart failure. Fetal echocardiogram is of great aid for the classification of the arrhythmia and for the detection of heart malformations. By applying combined real-time linear array and pulsed Doppler technique in cases of fetal cardiac arrhythmia, important information on the fetal circulatory state can be obtained. Estimations of the volume blood flow guide the clinician in the practical handling of these cases. Volume blood-flow estimations can probably detect imminent fetal heart failure. Therapeutic effects can be followed, and the timing of delivery can be optimized taking the circulatory state into account. Within the fetal heart rate range 50 to 250 beats/min adequate blood circulation is usually maintained in the fetus. The peak velocity, the acceleration, and the rising slope are all increased in the postextrasystolic beat, indicating the existence of postextrasystolic potentiation in the fetal heart. These three parameters can be related to the ventricular filling time, supporting the opinion that the fetal heart follows the rules of the Frank Starling relationship. Fetal arrhythmias constitute also an experimental model for the study of fetal cardiac physiology. 相似文献