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81.
82.
83.
Anxiety in patients undergoing MR imaging 总被引:6,自引:0,他引:6
To determine and quantify the major sources of anxiety for patients undergoing magnetic resonance (MR) imaging and to suggest means by which to eliminate or diminish their negative effects, the authors studied anxiety in 46 subjects. Of these, 20 randomly selected subjects who successfully completed the examination participated in exit interviews. Six subjects who terminated the examination before completion also completed exit interviews. Pre-imaging and postimaging questionnaires (state-trait anxiety inventory) were administered to measure anxiety in the 20 other subjects. Anxiety was associated with the constrictive dimensions of the magnet bore, examination duration, coil noise, and temperature within the bore. Preparation at the point of referral was consistently absent, incomplete, or misleading. Patients used identifiable strategies to cope with the examination: blinding, breathing relaxation techniques, visualization of pleasant images, and performance of mental exercises. 相似文献
84.
Di Chiro G; Girton ME; Frank JA; Dietz MJ; Gansow OA; Wright DC; Dwyer AJ 《Radiology》1986,160(1):221-222
Canine cerebrospinal fluid rhinorrhea, which occurs frequently in purebred beagles, was demonstrated in two dogs on magnetic resonance images after cisternal introduction of gadolinium-DTPA dimeglumine. 相似文献
85.
对人流感病毒A/Udorn/72(H_3N_2)株与禽类流感病毒A/Mallard/NY/78/(H_2N_2)重组后的重组株分析表明,仅含禽类病毒的核蛋白(NP)或膜蛋白(M)的RNA片段的重组株,在松鼠猴的呼吸道繁殖是受限制的。另外。仅有禽类的RNAl和NS基因的重组株(Clone 12)在松鼠猴的气管内的繁殖也明显受限制,而只具有其中一个基因的Clone 9, Clone 2, 则限制就不明显。由此表明,禽类流感病毒的NP和M基因在宿主范围的繁殖限制中起主要作用,而RNAI和SN基因的结合,同样起着繁殖受限制作用。 相似文献
86.
STEWART AJ; ALLEN JD; ADGEY AAJ 《QJM : monthly journal of the Association of Physicians》1992,85(1):761-769
SUMMARY In 56 patients, frequency analysis of the electrocardiogramof ventricular fibrillation exhibited power spectra with a distinctdominant frequency. The greatest success for resuscitation fromventricular fibrillation is recorded when ventricular fibrillationdevelops after the patient comes under coronary care. Of the41 patients in whom the onset and first 8 s of ventricular fibrillationwere artefact-free the mean dominant frequency of primary ventricularfibrillation (no cardiogenic shock or cardiac failure) in 21patients was 6.2±0.2 Hz, significantly higher than themean dominant frequency of the first 8 s of secondary ventricularfibrillation (cardiogenic shock or heart failure) (4.0±0.2Hz, 20 patients, p =0.0001). In these patients the peak-to-troughamplitude (ECG) of the first 8 s of ventricular fibrillationwas similar in both primary and secondary ventricular fibrillationas was the mean duration of ventricular fibrillation prior tothe first DC shock. There was a significantly lower successrate for resuscitation from secondary ventricular fibrillation(6 of 20 patients) compared with resuscitation from primaryventricular fibrillation (18 of 21 patients, x2 17.8, p=0.001).Of the remaining 15 patients who were collapsed between 3 and20 min before the arrival of the mobile coronary care unit,the dominant frequency of the first 8 s of ventricular fibrillationfell with increased duration of collapse (from 5.5 Hz at 3 minto a mean of 2.1 Hz at 20 min). Four of these 15 patients whosurvived the initial arrest had a mean dominant frequency of5.2±0.3 Hz, which was significantly higher than the meandominant frequency (3.1±0.3 Hz, p<0.01) of the 11patients who were not resuscitated. This study shows that low frequency ventricular fibrillationis indicative of a poor chance of successful resuscitation.Alteration of the frequency may increase resuscitation success. 相似文献
87.
O'Mahony S; Morris AJ; Straiton M; Murray L; MacKenzie JF 《QJM : monthly journal of the Association of Physicians》1996,89(9):685-690
We report our experience with small-bowel push enteroscopy in 50 patients.
The indications for push enteroscopy were: anaemia/occult gastrointestinal
bleeding (22 patients); overt gastrointestinal bleeding (17 patients);
abnormal small-bowel radiology (8 patients) and miscellaneous (3 patients).
In those with undiagnosed gastrointestinal bleeding/anaemia, abnormalities
were detected in 24/39 patients (62%): small bowel arteriovenous
malformations (AVMs) were detected in 19 (49%), and five (13%) had lesions
in the upper gastrointestinal tract. Seventeen patients had heater-probe
ablation therapy of vascular lesions: nine patients had small-intestinal
lesions, four patients gastric lesions, and four patients combined gastric
and small- intestinal lesions. In those with abnormal small-bowel
radiology, abnormalities were detected in 6/8 patients. We conclude that
(i) push enteroscopy can establish a diagnosis in a high proportion of
patients with gastrointestinal bleeding; (ii) heater-probe ablation therapy
of vascular lesions can be performed routinely at the time of enteroscopy;
(iii) a significant proportion of patients (9/50) referred for enteroscopy
with undiagnosed gastrointestinal bleeding have lesions in the
stomach/proximal duodenum missed at diagnostic endoscopy. Push enteroscopy
is a valuable diagnostic and therapeutic endoscopic procedure.
相似文献
88.
89.
目的:基质金属蛋白酶在急性心肌梗死后的心室重构中起着重要作用,但其调节机制目前尚未明确。实验拟通过动物模型的建立及体外细胞培养,观察急性心肌梗死后单个核细胞表面CD147与心肌成纤维细胞基质金属蛋白酶-9 mRNA表达的关系。
方法:实验于2006—08/2007-06在河北省人民医院临床实验中心完成。实验材料:SD大鼠及SD仔鼠(出生1~3d)购自河北医科大学试验动物中心。实验过程中对动物处置符合动物伦理学标准。实验方法:①将30只大鼠随机分为急性心肌梗死组(n=15)和假手术组(n=15),假手术组只过线不结扎。流式细胞分析法检测大鼠术后24h外周血单个核细胞表面CD147表达。②选择SD仔鼠制备心肌成纤维细胞。将单个核细胞与心肌成纤维细胞以细胞数0.5:1,1:1,2:1混合培养24h后,半定量反转录一聚合酶联反应法检测基质金属蛋白酶-9 mRNA表达。当单核细胞与心肌成纤维细胞2:1混合时,加入CD147单克隆抗体1,2,4μL/L,培养24h后检测基质金属蛋白酶-9 mRNA表达。
结果:①急性心肌梗死后外周血单个核细胞表面CD147表达明显增加。②单个核细胞与心肌成纤维细胞混合培养,随着单个核细胞比例的增加,心肌成纤维细胞基质金属蛋白酶-9 mRNA表达增加。③在单个核细胞与心肌成纤维细胞2:1混合培养体系中,随着加入CD147单克隆抗体浓度的增加,基质金属蛋白酶-9 mRNA生成减少。
结论:急性心肌梗死后单个核细胞表面CD147表达明显增加,对心肌成纤维细胞基质金属蛋白酶-9生成起上游调节作用。 相似文献
90.
Impact of an infection consultation service for bacteraemia on clinical management and use of resources 总被引:2,自引:0,他引:2
Nathwani D; Davey P; France AJ; Phillips G; Orange G; Parratt D 《QJM : monthly journal of the Association of Physicians》1996,89(10):789-797
Since 1993, the infection consultation service for bacteraemia has seen 310
patients in the Medical and Surgical Directorates at Ninewells Hospital and
Kings Cross Hospital. A random sample of 100 was audited. Case-notes were
incomplete for five patients, leaving 95 fully-audited patients. Clinical
outcome measures were death from infection, and readmission within 2 weeks
of discharge. Initial treatment was inconsistent with antibiotic policy in
46 patients (48%). Antibiotic treatment was changed in 37 (80%) of these
patients: increased in intensity in 19 (41%) and decreased in 18 (39%).
Changes were also made in 30 (61%) of the 49 patients whose initial
treatment was consistent with sepsis policy-increased in seven (14%) and
decreased in 23 (47%). Median daily antibiotic costs were lowered in
patients whose initial treatment was consistent with sepsis policy (pounds
10.10 vs. pounds 7.28, p = 0.0274). However, in the other patients, savings
were balanced by increases (p = 0.7696). Consultation required one
consultant session per week (3.5 h) and the audit required an additional 16
consultant sessions. Seven patients died, but only one death was directly
related to infection. Six patients were readmitted to hospital within 2
weeks, in three due to recurrence of infection. Changes to treatment were
recommended in the majority of patients, regardless of whether initial
treatment complied with the sepsis policy. The service primarily
redistributed resources rather than reducing costs. A fully audited service
requires considerable consultant time, but we believe such time is well
spent.
相似文献