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排序方式: 共有5979条查询结果,搜索用时 15 毫秒
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Emmanouil S. Brilakis MD PhD Michael Lee MD Julinda Mehilli MD Konstantinos Marmagkiolis MD Josep Rodes-Cabau MD Rajesh Sachdeva MD Anna Kotsia MD George Christopoulos MD Bavana V. Rangan BDS MPH Atif Mohammed MD Subhash Banerjee MD 《Current treatment options in cardiovascular medicine》2014,16(5):1-12
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Rinkesh K. Bansal Narendra S. Choudhary Saurabh K. Patle Amit Agarwal Gagandeep Kaur Haimanti Sarin Rajesh Puri 《Indian journal of gastroenterology》2018,37(2):108-112
Background
Fine-needle aspiration (FNA) of adrenals is needed in patients with pyrexia of unknown origin (PUO) and adrenal enlargement in absence of other diagnostic clues. Adrenals are easily accessible by endoscopic ultrasound (EUS) due to proximity; however, there is no systemic study available on FNA of adrenals in patients with PUO. The aim of this study was to evaluate the diagnostic yield and safety of EUS-FNA of enlarged adrenal in patients with PUO.Methods
Data was analyzed from October 2010 to September 2016 at a single tertiary care center in northern India. EUS-FNA of enlarged adrenals was done in 52 patients for the etiological diagnosis of PUO in whom a definitive diagnosis could not be made with other means.Results
The mean age was 48±14 years; 36 were males and 16 were females. EUS-FNA was done from the left adrenal in 50 patients and from the right sample in 2 patients. A technical success was achieved in 100% cases. The 19-G needle was used in the majority (75%) to the presence of necrotic areas in adrenals; median numbers of passes were 2. The cytopathological diagnoses were tuberculosis (n?=?36), histoplasmosis (n?=?13), lymphoma (n?=?2), and metastasis from undiagnosed neuroendocrine tumor of lung (n?=?1). Thus, a diagnosis could be made in 52/52 (100%) patients. None of the patients had any procedure-related complications.Conclusions
EUS-FNA is a safe and effective method for evaluating etiology of PUO in patients with adrenal enlargement.76.
Evaluations of HIV type 1 rev gene diversity and functional domains following perinatal transmission
Ramakrishnan R Hussain M Holzer A Mehta R Sundaravaradan V Ahmad N 《AIDS research and human retroviruses》2005,21(12):1035-1045
The human immunodeficiency virus type 1 (HIV-1) rev exons 1 and 2 sequences were analyzed from six mother-infant pairs following perinatal transmission. The rev open reading frame was maintained with a frequency of 93.96% in six mother-infant pairs' sequences. There was a low degree of viral heterogeneity and estimates of genetic diversity in mother-infant pairs' rev sequences. However, the distances of rev sequences between epidemiologically unlinked individuals were greater than in epidemiologically linked mother-infant pairs. Furthermore, phylogenetic parameters revealed that the epidemiologically linked mother-infant pairs were closer evolutionarily to each other as compared with epidemiologically unlinked mother-infant pairs. Both mothers and infants were under positive selection pressure as determined by the ratios of nonsynonymous to synonymous substitutions. The functional domains required for Rev activity, including nuclear export of RNA, RNA binding domain, and nuclear import signals, were conserved in all mother-infant pairs' sequences. The conservation of functional domains of rev and a low degree of heterogeneity following vertical transmission are consistent with an indispensable role of rev in the HIV-1 life cycle. 相似文献
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This study examined the feasibility and potential clinical utility of magnetic resonance imaging (MRI) evaluation of myocardial perfusion (first-pass contrast enhancement) and viability (myocardial delayed enhancement) in 30 patients with congenital and acquired pediatric heart disease. Good agreement was found between MRI evaluation of myocardial perfusion and viability and analysis of segmental wall motion as well as coronary angiography (n = 10) and single photon emission computed tomography (n = 6). 相似文献
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