全文获取类型
收费全文 | 832篇 |
免费 | 78篇 |
专业分类
耳鼻咽喉 | 24篇 |
儿科学 | 40篇 |
妇产科学 | 15篇 |
基础医学 | 169篇 |
口腔科学 | 2篇 |
临床医学 | 53篇 |
内科学 | 83篇 |
皮肤病学 | 5篇 |
神经病学 | 235篇 |
特种医学 | 6篇 |
外科学 | 101篇 |
综合类 | 12篇 |
预防医学 | 108篇 |
眼科学 | 1篇 |
药学 | 38篇 |
肿瘤学 | 18篇 |
出版年
2020年 | 9篇 |
2018年 | 8篇 |
2017年 | 17篇 |
2016年 | 12篇 |
2015年 | 15篇 |
2014年 | 15篇 |
2013年 | 26篇 |
2012年 | 40篇 |
2011年 | 34篇 |
2010年 | 19篇 |
2009年 | 24篇 |
2008年 | 30篇 |
2007年 | 34篇 |
2006年 | 34篇 |
2005年 | 23篇 |
2004年 | 26篇 |
2003年 | 34篇 |
2002年 | 22篇 |
2001年 | 16篇 |
2000年 | 17篇 |
1999年 | 14篇 |
1998年 | 11篇 |
1997年 | 13篇 |
1996年 | 8篇 |
1995年 | 8篇 |
1993年 | 11篇 |
1992年 | 21篇 |
1991年 | 22篇 |
1990年 | 25篇 |
1989年 | 24篇 |
1988年 | 17篇 |
1987年 | 10篇 |
1986年 | 14篇 |
1985年 | 17篇 |
1984年 | 18篇 |
1983年 | 15篇 |
1982年 | 19篇 |
1981年 | 14篇 |
1980年 | 10篇 |
1979年 | 16篇 |
1978年 | 15篇 |
1977年 | 11篇 |
1976年 | 9篇 |
1975年 | 16篇 |
1974年 | 9篇 |
1973年 | 12篇 |
1972年 | 8篇 |
1971年 | 9篇 |
1970年 | 7篇 |
1969年 | 8篇 |
排序方式: 共有910条查询结果,搜索用时 15 毫秒
851.
I T Campbell R P Morton J A Cole C H Raine L M Shapiro P M Stell 《The American journal of clinical nutrition》1983,38(6):870-878
Ten patients were fed by nasogastric tube for 5 days after major surgery of the head and neck. Five were fed by continuous infusion 24 h/day using an enteral nutrition pump and five were fed comparable quantities by 2-h bolus administration between 0600 and 2200 h. Those fed by bolus had lower resting oxygen consumption on the 4th and 5th postoperative days and better cumulative nitrogen balance over the 5 days than the continuously fed group. It appears that metabolically it may be better to use an intermittent feeding regimen than a continuous one when feeding patients postoperatively via a nasogastric tube. 相似文献
852.
853.
In order to determine the relationships between allograft function and the recipient's plasma concentrations of atrial natriuretic factor (ANF), plasma ANF was measured by radioimmunoassay for 14 days after cadaveric renal transplantation in 9 patients aged 19-64 years. All received immunosuppression with prednisolone, azathioprine, and cyclosporine. No patient was in heart failure. During the study period, six grafts functioned, and three were nonfunctioning--two due to rejection and one to acute tubular necrosis. Plasma ANF concentration at the time of transplantation was 48 +/- 16 pmol/L (mean +/- SEM) range 15-145 pmol/L. In the six patients with functioning grafts, ANF declined in parallel with the fall in serum creatinine (658 +/- 35 to 210 +/- 34 mumol/L). In the three with nonfunctioning grafts, serum creatinine and plasma ANF concentration both increased. There was overall a significant linear relation between serum creatinine and plasma ANF (r = 0.527, P less than 0.001). The changes in plasma ANF after renal transplantation bore no relationship to changes in body weight or blood pressure. However, plasma ANF concentration was related to allograft fractional sodium excretion (r = 0.687, p less than 0.001). We conclude that elevated plasma ANF concentrations in end-stage renal disease are restored to normal by successful renal transplantation, implying that renal function is a determinant of plasma ANF concentration. Circulating plasma ANF may also have a direct effect on allograft sodium excretion. 相似文献
854.
Left ventricular hypertrophy and ambulatory blood pressure monitoring in chronic renal failure 总被引:15,自引:4,他引:11
Tucker B; Fabbian F; Giles M; Thuraisingham RC; Raine AE; Baker LR 《Nephrology, dialysis, transplantation》1997,12(4):724-728
BACKGROUND: Left ventricular hypertrophy (LVH) is both common and an
important predictor of risk of death in end-stage renal failure (ESRF). In
mild to moderate chronic renal failure (CRF), the timing of onset of LVH
and the factors involved in its initial development have not been fully
elucidated. The present study was undertaken to examine the prevalence and
potential determinants of echocardiographically determined LVH in this
connection, and to compare 24-h ambulatory blood pressure (BP) recordings
with BP measured at a previous clinic visit. METHODS: From a cohort of 120
non-diabetic patients who had been attending a nephrology clinic, 118
agreed to participate in the study. Of these we selected for analysis 85
stable patients (37 male). Patients with known cardiovascular disease,
those with a history of poor compliance with antihypertensive medication,
and those in whom such medication had been changed in the previous 3 months
were excluded. Clinic BP, 24-h ambulatory BP, echocardiography, body mass
index (BMI), serum creatinine (SCr), creatinine clearance (CrCl),
haemoglobin (Hb), fasting cholesterol (CHOL), triglyceride TRIGL), plasma
glucose, calcium (Ca), phosphate (PO4), alkaline phosphatase (ALK PHOS),
parathyroid hormone (PTH) concentrations, and 24-h urinary protein were
assessed in all patients. Seventy-seven per cent were on antihypertensive
medication. RESULTS: LVH was detected in 16% of patients with CrCL > 30
ml/min, and 38% of patients with CrCl < 30 ml/min. By stepwise
regression analysis, ambulatory systolic BP (P < 0.0001), male gender (P
< 0.0001), BMI (P < 0.0002), and Hb concentration (P < 0.002) were
the only independent determinants of left ventricular (LV) mass. Nocturnal
systolic BP (P < 0.02) was the main determinant of LVH in the group of
patients with advanced CRF. The correlation between left ventricular mass
index (LVMI) and mean 24-h ambulatory systolic BP (r = 0.52, 95% confidence
interval 0.50-0.54) was statistically significantly stronger than with
outpatient systolic BP (r = 0.25, 95% confidence interval 0.23-0.27). The
same was true for the correlation between LVMI and mean 24-h ambulatory
diastolic BP (r = 0.42, 95% confidence interval 0.40-0.44), and outpatient
diastolic BP (r = 0.22, 95% confidence interval 0.20-0.24). CONCLUSIONS:
Twenty-four hour ambulatory BP recording and echocardiography are required
for accurate diagnosis of inadequate BP control and early LVH in patients
with chronic renal impairment, independent determinants of which are
hypertension, male sex, BMI, and anaemia.
相似文献
855.
856.
857.
H S Nelson D Raine H C Doner W C Posey 《The American review of respiratory disease》1977,116(5):871-878
Evidence of bronchodilator subsensitivity was sought in studies using the specific beta2 adrenergic agonist, albuterol. After a period of 1 or 2 weeks off all oral sympathomimetic agents, the mean response of the patients to the first dose of albuterol was consistently greater than the response after a period during which the drug had been administered regularly. Maximal decrease in response occurred after 2 weeks' of treatment, and there was no further decrease after prolonged treatment with the same dose of albuterol for periods as long as 1 year. 相似文献
858.
859.
860.