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71.
SDS Polyacrylamide Gel Characterization of Serum FDP Produced in Response to Ancrod and Streptokinase/Plasminogen Infusions in Man 总被引:1,自引:0,他引:1
D. A. Lane Patricia A. Robbins M. W. Rampling V. V. Kakkar 《British journal of haematology》1977,36(1):137-148
S ummary . The serum FDP produced in response to defibrination with ancrod and to thrombolytic therapy with intermittent streptokinase/plasminogen infusion have been characterized using a method of solid phase immuno-precipitation followed by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate. Using this method it is possible to distinguish between the plasmin degradation products of fibrinogen and factor XIIIa induced crosslinked fibrin. During ancrod administration, fragments of similar mobility to fibrinogen fragments X, Y, D and E are present in serum samples taken 24 h after the initiation of treatment, while subsequent samples contain mainly fragments with the same mobility as fibrinogen fiagment D. The intermittent nature of the streptokinase/plasminogen infusions produces fibrinogen fragments X, Y, D and E in the serum 1 h after each daily streptokinase/plasminogen administration. An early clearance of fragment E from the circulation of patients receiving either ancrod or streptokinase/plasminogen infusions accords with the results of other investigations. The presence of the D dimer fragment, which is produced only by plasmin lysis of factor XIIIa crosslinked fibrin, could not be conclusively confirmed in either group of patients. 相似文献
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Rahul S. Bhansali Malini Rammohan Paul Lee Anouchka P. Laurent Qiang Wen Praveen Suraneni Bon Ham Yip Yi-Chien Tsai Silvia Jenni Beat Bornhauser Aurlie Siret Corinne Fruit Alexandra Pacheco-Benichou Ethan Harris Thierry Besson Benjamin J. Thompson Young Ah Goo Nobuko Hijiya Maria Vilenchik Shai Izraeli Jean-Pierre Bourquin Sbastien Malinge John D. Crispino 《The Journal of clinical investigation》2021,131(1)
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Prem Kumar Rathod Rahul Yadav Ongkila Bhutia Ajoy Roychoudhury Krushna Bhatt Kamalpreet Kaur 《Journal of oral and maxillofacial surgery》2021,79(6):1328.e1-1328.e13
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Preethi Jeyaraman Narendra Agrawal Rahul Bhargava Divya Bansal Rayaz Ahmed Dinesh Bhurani Sachin Bansal Neha Rastogi Pronamee Borah Rahul Naithani 《Transfusion and apheresis science》2021,60(3):103075
BackgroundData on convalescent plasma therapy (CPT) in patients of hematological malignancies with severe Covid-19 is scarce.ObjectiveTo study 14-day mortality in patients who received CPT.Patients & methodsRetrospective multicentre observational study conducted in 4 centres treating haematological malignancies across Delhi-national capital region. Total 33 haematological malignancies patients with severe Covid-19 who received CPT were analysed.ResultsThe median age of the study cohort was 62 years (18–80 years). Twenty one percent patients had 1 comorbidity, 18 % had 2 comorbidities and 6% patients had 3 and 5 comorbidities each. Twenty four patients were on active therapy. Sixty nine percent of patients required ICU stay. Twenty five patients received plasma therapy within 7 days (early) of diagnosis of Covid-19 infection. Median day of plasma infusion from date of diagnosis of Covid-19 infection was 4 days (range: 2–25 days). Patient who had early initiation of plasma therapy had shorter duration of hospitalisation (12.7 vs 24.3 days, p = 0.000). Overall mortality in the cohort was 45.5%. There was no effect of disease status, active therapy, presence of comorbidity on mortality. There was no difference in the mortality in patients receiving early vs late initiation of plasma therapy or in patients receiving one versus two plasma therapy.ConclusionsWe provide a large series of patients with hematological malignancies and role of CPT in this group. 相似文献
78.
Veldtman Gruschen Possner Mathias Mohty Dania Issa Ziyad Alsaleh Monerah AlMarzoog AlJuhara Thaar Emmanual Shisamma Salam Yezan AlHabdan Mohammed Saleh Alsaied Tarek Rathod Rahul H. Siblini Ghassan Vriz Olga 《The international journal of cardiovascular imaging》2021,37(9):2651-2660
The International Journal of Cardiovascular Imaging - Abnormal atrial mechanics in biventricular circulations have been associated with elevated left heart filling pressures. Similar associations... 相似文献
79.
Purpose
Conjoined twins are a rare complication of 9 monozygotic twins and are associated with high perinatal mortality. Pygopagus are one of the rare types of conjoined twins with only a handful of cases reported in the literature.Case summary
We present the case of one-and-half month-old male pygopagus conjoined twins, who were joined together dorsally in lower lumbar and sacral region and had spina bifida and shared a single thecal sac with combined weight of 6.14 kg. Spinal cord was separated at the level of the conus followed by duraplasty. They had uneventful recovery with normal 15 months follow-up.Conclusion
Separation of conjoined twins is recommended in where this is feasible with the anticipated survival of both or one infant.80.
Mulligan Kyle R. Ferland Catherine E. Gawri Rahul Borthakur Arijitt Haglund Lisbet Ouellet Jean A. 《European spine journal》2015,24(11):2395-2401
European Spine Journal - The aim of the study was to investigate if axial T1ρ MR images had similar accuracy as established sagittal T1ρ MRI for the assessment of proteoglycan... 相似文献