全文获取类型
收费全文 | 28529篇 |
免费 | 4118篇 |
国内免费 | 279篇 |
专业分类
耳鼻咽喉 | 779篇 |
儿科学 | 973篇 |
妇产科学 | 749篇 |
基础医学 | 2489篇 |
口腔科学 | 544篇 |
临床医学 | 3713篇 |
内科学 | 5836篇 |
皮肤病学 | 822篇 |
神经病学 | 3117篇 |
特种医学 | 822篇 |
外国民族医学 | 5篇 |
外科学 | 5013篇 |
综合类 | 186篇 |
现状与发展 | 2篇 |
一般理论 | 67篇 |
预防医学 | 3500篇 |
眼科学 | 614篇 |
药学 | 1230篇 |
1篇 | |
中国医学 | 39篇 |
肿瘤学 | 2425篇 |
出版年
2024年 | 136篇 |
2023年 | 774篇 |
2022年 | 623篇 |
2021年 | 1191篇 |
2020年 | 1264篇 |
2019年 | 961篇 |
2018年 | 1505篇 |
2017年 | 1223篇 |
2016年 | 1394篇 |
2015年 | 1371篇 |
2014年 | 1831篇 |
2013年 | 2188篇 |
2012年 | 1918篇 |
2011年 | 1876篇 |
2010年 | 1446篇 |
2009年 | 1509篇 |
2008年 | 1445篇 |
2007年 | 1386篇 |
2006年 | 1250篇 |
2005年 | 1060篇 |
2004年 | 924篇 |
2003年 | 818篇 |
2002年 | 626篇 |
2001年 | 242篇 |
2000年 | 160篇 |
1999年 | 228篇 |
1998年 | 362篇 |
1997年 | 345篇 |
1996年 | 354篇 |
1995年 | 334篇 |
1994年 | 218篇 |
1993年 | 167篇 |
1992年 | 155篇 |
1991年 | 147篇 |
1990年 | 84篇 |
1989年 | 145篇 |
1988年 | 102篇 |
1987年 | 86篇 |
1986年 | 100篇 |
1985年 | 102篇 |
1984年 | 101篇 |
1983年 | 74篇 |
1982年 | 84篇 |
1981年 | 63篇 |
1980年 | 66篇 |
1978年 | 50篇 |
1977年 | 54篇 |
1976年 | 36篇 |
1975年 | 50篇 |
1972年 | 34篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
Kevin G Becker Insong J Lee James W Nagle Rachel D Canning Ameer M Gado Rosarelis Torres Mihael H Polymeropoulos Paul T Massa WilliamE Biddison Paul D Drew 《International journal of developmental neuroscience》1997,15(7):73
We describe a novel human zinc finger cNDA, C2H2-171. This cDNA represents an mRNA which encodes a protein of 484 amino acids and a calculated molecular weight of 54 kD. Four zinc finger-like domains are found in the C-terminal end of the protein. At the N-terminus, C2H2-171 contains a POZ/tramtrack-like domain similar to that found in the tumor associated zinc finger proteins LAZ-3/BCL-6 and PLZ-F, as well as in non-zinc finger proteins. C2H2-171 RNA is preferentially expressed in the brain, and increases during the course of murine development, with maximal expression in the adult. C2H2-171 RNA is differentially expressed in brain regions, with the highest level of expression in the cerebellum. C2H2-171 RNA was expressed at high levels in primary cerebellar granule cell neurons compared to astrocytes. The gene encoding C2H2-171 is highly conserved in vertebrates, and maps to the terminus of human chromosome 1 (1q44-ter). This chromosomal location is associated with a number of cytogenetic aberrations including those involving brain developmental anomalies and tumorigenesis. These data suggest that C2H2-171 may play an important role in vertebrate brain development and function. 相似文献
62.
Ladenstein Ruth; Pearce Rachel; Hartmann Olivier; Patte Catherine; Goldstone Tony; Philip Thierry 《Blood》1997,90(8):2921-2930
63.
64.
Patients'attitudes to rectal drug administration 总被引:2,自引:0,他引:2
One hundred adult patients attending for day case surgery were surveyed by anonymous questionnaire in order to determine their attitudes to rectal drug administration. Fifty four patients did not want an analgesic drug (diclofenac sodium) administered rectally whilst under anaesthesia, all preferring to take it orally if available. Ninety eight patients thought that drugs administered per rectum should always be discussed with them beforehand and a few had very strong feelings about this route of administration. We suggest that prescribers of rectal diclofenac should always discuss it with patients pre-operatively. Whilst many are happy to have suppositories, some young patients are sensitive about this and prefer to take such medication by mouth. 相似文献
65.
66.
Robert D Bourke MB BS John Pyle MB BS; FRACO FRACS † 《Clinical & experimental ophthalmology》1994,22(1):77-80
Herpes zoster ophthalmicus (HZO) commonly causes isolated ophthalmoplegic syndromes. Visual loss caused by optic neuritis secondary to HZO can be reversible or irreversible. HZO rarely presents as an orbital apex syndrome, when an association with meningo-encephalitis has been reported. We report a case of orbital apex syndrome secondary to HZO treated with systemic steroids and acyclovir. Our patient suffered no systemic complications and displayed a rapid resolution of optic neuropathy. We discuss this case in the light of previous reports and explore the possible pathogenic mechanisms involved. 相似文献
67.
68.
Suppurative corneal ulceration in Bangladesh 总被引:8,自引:0,他引:8
AAS Dunlop MB BS ED Wright MRCPath † SA Howlader‡ I Nazrul‡ R Husain‡ K McClellan FRACO § FA Billson FRACO § 《Clinical & experimental ophthalmology》1994,22(2):105-110
Suppurative keratitis is an important preventable cause of blindness, particularly in the developing world. This study analyses 142 cases of suppurative keratitis referred to Chittagong Eye Infirmary, Bangladesh. Some 53.5% of cases were bacterial and 35.9% were fungal. The five most common pathogens were: Pseudomonas sp. 24%, Streptococcus pneumoniae 17%, Aspergillus sp. 13%, Fusarium sp. 7% and Curvularia sp. 6%. Gram stain and culture results were consistent in 62.6% of cases. Previous antibiotic treatment was a significant factor for failure of culture isolation and less so for Gram stain failure. On Gram stain, 55.9% of pseudomonal cases were missed, but only 2% of fungal cases were missed. Over all, Gram stain had a sensitivity of 62% and positive predictive value of 84% for bacterial cases, and 98% and 94% for fungal cases, respectively. Fungal ulcers were typically filamentous, but an antecedent history of trauma was not common. The most frequent injury was due to rice grains, but the inoculum appeared to be introduced during eye washing with contaminated water. Pseudomonal ulcers occurred most frequently in the monsoon season, and Fusarium cases were seen only in the hot, dry season. 相似文献
69.
Mark Ellis FRACO FRACS Ross Drewe MB BS DO † Justin O'Day FRACO FRACS 《Clinical & experimental ophthalmology》1994,22(2):119-123
Desmoplastic malignant melanoma (DMM) is a rare variant of spindle cell melanoma. We report a case of DMM of the forehead secondarily involving the orbit. The diagnosis was based on light microscopic features, including prominent peripheral cell nest formation and spindle cell fascicles in densely collagenous stroma. Immunohistochemical studies showed strong uniform staining for S100 antigen throughout the tumour. It was negative for HMB 45, smooth muscle actin, desmin, cytokeratins and Type IV collagen. Electron microscopy showed neither melanosomes nor myelin figures. The clinical and histological characteristics of desmoplastic malignant melanoma, and its differential diagnosis of malignant schwannoma, are discussed. DMM has a poor prognosis, since it tends to invade deeply, recur locally and metastasise readily. 相似文献
70.
Maryla Z Stelmach MB BS Justin O'Day FRACO FRACS † Hugh Ryan FRACO FRACS ‡ 《Clinical & experimental ophthalmology》1994,22(2):139-143
The history and clinical findings are presented of a patient who suffered from the uveal effusion syndrome over a 10-year period from 1956. The funduscopic appearance is illustrated both at the time of initial presentation and 36 years later. This condition typically affects healthy middle-aged men and causes recurrent, spontaneous, serous retinal and ciliochoroidal detachments, often resulting in significant visual impairment. Two separate hypotheses have been postulated to explain the pathogenesis of the uveal effusion syndrome, one relating to abnormally thickened sclera, the other to chronic bulbar hypotony. Both are discussed, as is the rationale behind the current management of this unusual condition. 相似文献