全文获取类型
收费全文 | 9152篇 |
免费 | 501篇 |
国内免费 | 95篇 |
专业分类
耳鼻咽喉 | 67篇 |
儿科学 | 208篇 |
妇产科学 | 188篇 |
基础医学 | 1038篇 |
口腔科学 | 268篇 |
临床医学 | 678篇 |
内科学 | 2430篇 |
皮肤病学 | 239篇 |
神经病学 | 866篇 |
特种医学 | 336篇 |
外科学 | 1677篇 |
综合类 | 32篇 |
一般理论 | 2篇 |
预防医学 | 454篇 |
眼科学 | 75篇 |
药学 | 458篇 |
中国医学 | 11篇 |
肿瘤学 | 721篇 |
出版年
2023年 | 84篇 |
2022年 | 130篇 |
2021年 | 292篇 |
2020年 | 159篇 |
2019年 | 207篇 |
2018年 | 278篇 |
2017年 | 197篇 |
2016年 | 246篇 |
2015年 | 279篇 |
2014年 | 354篇 |
2013年 | 445篇 |
2012年 | 657篇 |
2011年 | 697篇 |
2010年 | 401篇 |
2009年 | 360篇 |
2008年 | 573篇 |
2007年 | 578篇 |
2006年 | 582篇 |
2005年 | 568篇 |
2004年 | 483篇 |
2003年 | 447篇 |
2002年 | 383篇 |
2001年 | 108篇 |
2000年 | 100篇 |
1999年 | 95篇 |
1998年 | 74篇 |
1997年 | 72篇 |
1996年 | 51篇 |
1995年 | 54篇 |
1994年 | 48篇 |
1993年 | 43篇 |
1992年 | 51篇 |
1991年 | 63篇 |
1990年 | 59篇 |
1989年 | 41篇 |
1988年 | 53篇 |
1987年 | 46篇 |
1986年 | 45篇 |
1985年 | 43篇 |
1984年 | 37篇 |
1983年 | 23篇 |
1982年 | 20篇 |
1981年 | 15篇 |
1979年 | 22篇 |
1977年 | 11篇 |
1974年 | 15篇 |
1973年 | 12篇 |
1968年 | 11篇 |
1967年 | 10篇 |
1966年 | 10篇 |
排序方式: 共有9748条查询结果,搜索用时 156 毫秒
21.
Romano Maurizio; Dri Pietro; Dadalt Liviana; Patriarca Pierluigi; Baralle Francisco E. 《Blood》1997,90(10):4126-4134
22.
23.
Alfonso Fasano Antonio E Elia Arianna Guidubaldi Pietro A Tonali Anna Rita Bentivoglio 《Movement disorders》2007,22(4):564-566
We report a case of cervical dystonia occurring in a 33-year-old without personal history of movement disorder but with family history of essential tremor, primigravid, primiparous woman at 1 weeks' amenorrhea, resolved completely after delivery in the course of 3 months. Dystonia never recurred in the following 5 years. Several neurological disorders are known to occur or worsen during pregnancy. As far as we know, this is the second reported case of dystonia occurring during pregnancy, thus confirming that dystonia gravidarum represents a new entity and should be considered in women of reproductive age affected by dystonia, especially when presenting with rapid-onset cervical dystonia. 相似文献
24.
25.
26.
Kenneth P Wright Jr. Pietro Badia Bryan L Myers Steven C Plenzler Milton Hakel 《Brain research》1997,747(1):654
The effects of caffeine ingestion and exposure to bright light, both separately and in combination, on salivary melatonin and tympanic temperature were assessed in humans. Four treatments during a 45.5 h sleep deprivation period were compared: Dim Light-Placebo, Dim Light-Caffeine, Bright Light-Placebo and Bright-Light Caffeine. The Dim Light-Caffeine condition (200 mg twice each night) relative to the Dim Light-Placebo condition suppressed nighttime melatonin levels and attenuated the normal decrease in temperature. Combining caffeine ingestion with bright light exposure (≥2000 lux) suppressed melatonin and attenuated the normal nighttime drop in temperature to a larger degree than either condition alone; i.e. effects were additive. Circadian effects were also observed in that the amplitude and phase of the temperature rhythm were altered during treatment. These findings establish that the human melatonin system is responsive to caffeine. Other evidence suggests that caffeine may influence melatonin and temperature levels through antagonism of the neuromodulator adenosine. 相似文献
27.
Claudia Giaroli Gianfranco Riccò Gianni Vecchi Stefano Belli Caterina Bruno Mario Grignoli Silvia Candela Salvatore Minisci Roberto Poletti Guiseppina Venturi Antonio Ziccardi Pietro Comba 《International archives of occupational and environmental health》1994,66(1):7-11
The present study describes cause-specific mortality of asbestos cement workers in the Emilia Romagna region of Italy. The cohort included workers in ten factories, most of which started operating between 1955 and 1965. Asbestos, mainly chrysotile, constituted 10%–20% of the dry component of the mixture. Crocidolite range between 5% and 50% of total asbestos. Asbestos concentrations up to 44 ff/cc were reported prior to 1975, while in recent years they have usually been below 0–1 ff/cc. The cohort included 3341 workers who had at some time been employed in the ten factories under study. Their mortality experience was compared with that of the population resident in Emilia Romagna. Vital status was ascertained at 1989. Seventy-three subjects were lost to followup (2.2%). Mortality from all causes and from all types of cancer was increased in the cohort. Malignant neoplasms of the respiratory tract showed a significant increase (SMR: 134; 90% confidence interval: 101–175; 40 observed) due to lung cancer (SMR: 124; 90% confidence interval: 91–166; 33 observed) and neoplasms of the pleura, mediastinum, and other parts of the respiratory tract (SMR: 602; 90% confidence interval 237–1267; 5 observed). The discrepancy between observed and expected mortality mainly concerned subjects with at least 20 years of employment in the factories. Five more cases of histologically confirmed mesothelioma occurred after the end of follow-up. 相似文献
28.
F Hess C Jerusalem S Steeghs O Reijnders B Braun P Grande 《The Journal of cardiovascular surgery》1992,33(3):358-365
The development and long-term fate of the inner cellular lining in 72 small caliber (3 mm inner diameter) fibrous polyurethane vascular prostheses explanted from dog carotid and/or femoral arteries at times ranging from 1.5 weeks up to 53 months after implantation were studied by scanning electron and light microscopy. A continuous cellular ingrowth from the vascular stumps into the 3 cm long prostheses was observed, which eventually resulted in a complete cellular lining 6 months after implantation. No other ways of endothelialization were noted. In fully endothelialized prostheses, the cellular ingrowth extended approximately 8 mm into the prostheses and consisted of several layers of fibroblasts and smooth muscle cells, covered by a very thin endothelioid cell layer. The newly developed lining was firmly anchored onto the inner prosthetic surface by means of cellular protrusions extended into the fibrous texture of the prosthetic wall. It was concluded that under experimental conditions in the dog complete endothelialization can be obtained in fibrous polyurethane vascular prostheses and that the lining remained thin and stable throughout the observation period of 53 months after implantation. 相似文献
29.
Subcostal incision versus midline laparotomy in gallstone surgery: a prospective and randomized trial 总被引:1,自引:0,他引:1
J C García-Valdecasas R Almenara C Cabrer A M de Lacy M Sust P Taurá J Fuster L Grande M Pera J Sentis 《The British journal of surgery》1988,75(5):473-475
We report the results of a prospective and randomized trial designed to study the incidence of abdominal and pulmonary complications in gallstone surgery comparing subcostal (SI) with midline incision. The need for postoperative analgesia was lower in the SI group. There was no difference in the degree of hypoxaemia in the first two postoperative days, but there was less impairment of pulmonary function in terms of vital capacity and forced expiratory volume in 1 s (P less than 0.0001) in the SI group. SI patients also had a lower incidence of pulmonary or abdominal complications but the difference was not significant. Finally, we found a reduced hospital stay for the SI patients (P less than 0.01), probably related to a reduced postoperative analgesic requirement and an improved pulmonary function. We conclude that subcostal incision is a better approach for biliary tract surgery and should be used whenever possible. 相似文献
30.
Distribution of paresthesias in Carpal Tunnel Syndrome reflects the degree of nerve damage at wrist.
Pietro Caliandro Giuseppe La Torre Irene Aprile Costanza Pazzaglia Irene Commodari Pietro Tonali Luca Padua 《Clinical neurophysiology》2006,117(1):228-231
OBJECTIVE: To verify whether the distribution of paresthesias in patients with Carpal Tunnel Syndrome (CTS) is related to the degree of the neurophysiological involvement. METHODS: We performed a cross-sectional study and retrospectively evaluated 163 patients who referred to our electromyography lab and to which a clinical and electrophysiological diagnosis of CTS was made. We divided the patients into two groups: (1) patients complaining of paresthesias at the hand as a whole and (2) patients with paresthesias in the territory of the median nerve. We referred to the distribution of paresthesias at the hand as GLOVE and to the distribution in the territory of the median nerve as MEDIAN. We compared the neurophysiological impairment in GLOVE and MEDIAN distributions. Moreover, we performed multiple regression analysis to evaluate which clinical-neurophysiological variables determined GLOVE and MEDIAN distribution. RESULTS: In our sample, 70.4% of patients had GLOVE distribution and 29.6% of patients MEDIAN distribution. The risk of presenting MEDIAN distribution increases about twice (OR = 2.07; 95% IC: 1.51-2.83) for each unitary increment of neurophysiological class. CONCLUSIONS: The distribution of paresthesias reflects the degree of nerve damage at wrist; patients suffering of SEV/EXT CTS present MEDIAN distribution. SIGNIFICANCE: Our data have important clinical implications because they strongly suggest that we have to consider the possibility of a severe neurophysiological involvement of the median nerve at wrist in patients complaining of MEDIAN distribution. 相似文献