全文获取类型
收费全文 | 124760篇 |
免费 | 8128篇 |
国内免费 | 537篇 |
专业分类
耳鼻咽喉 | 1317篇 |
儿科学 | 3674篇 |
妇产科学 | 2120篇 |
基础医学 | 16548篇 |
口腔科学 | 2219篇 |
临床医学 | 12305篇 |
内科学 | 26475篇 |
皮肤病学 | 1488篇 |
神经病学 | 12056篇 |
特种医学 | 3896篇 |
外国民族医学 | 1篇 |
外科学 | 17874篇 |
综合类 | 1666篇 |
现状与发展 | 1篇 |
一般理论 | 156篇 |
预防医学 | 10799篇 |
眼科学 | 3324篇 |
药学 | 8859篇 |
1篇 | |
中国医学 | 285篇 |
肿瘤学 | 8361篇 |
出版年
2023年 | 615篇 |
2022年 | 1090篇 |
2021年 | 2387篇 |
2020年 | 1434篇 |
2019年 | 2434篇 |
2018年 | 2839篇 |
2017年 | 2062篇 |
2016年 | 2394篇 |
2015年 | 2775篇 |
2014年 | 3999篇 |
2013年 | 5609篇 |
2012年 | 8566篇 |
2011年 | 9198篇 |
2010年 | 5033篇 |
2009年 | 4679篇 |
2008年 | 8101篇 |
2007年 | 8584篇 |
2006年 | 8127篇 |
2005年 | 8172篇 |
2004年 | 7739篇 |
2003年 | 7117篇 |
2002年 | 6862篇 |
2001年 | 1241篇 |
2000年 | 951篇 |
1999年 | 1262篇 |
1998年 | 1465篇 |
1997年 | 1236篇 |
1996年 | 961篇 |
1995年 | 960篇 |
1994年 | 810篇 |
1993年 | 796篇 |
1992年 | 689篇 |
1991年 | 631篇 |
1990年 | 571篇 |
1989年 | 521篇 |
1988年 | 524篇 |
1987年 | 494篇 |
1986年 | 434篇 |
1985年 | 510篇 |
1984年 | 578篇 |
1983年 | 533篇 |
1982年 | 700篇 |
1981年 | 614篇 |
1980年 | 543篇 |
1979年 | 380篇 |
1978年 | 353篇 |
1977年 | 352篇 |
1976年 | 298篇 |
1975年 | 282篇 |
1974年 | 289篇 |
排序方式: 共有10000条查询结果,搜索用时 11 毫秒
81.
Paul Saenger Kenneth M. Attie Joan DiMartino-Nardi Richard N. Fine 《Pediatric nephrology (Berlin, Germany)》1996,10(3):261-263
Carbohydrate metabolism was evaluated by fasting and postprandial glucose, insulin, and hemoglobin (Hb)A1c levels in children with chronic renal insufficiency and various other growth disorders treated with growth hormone. Mean fasting and postprandial glucose remained unchanged throughout the 5-year study period in all four study groups. Median fasting insulin levels rose from lownormal levels into the normal range after 5 years of growth hormone. Average fasting insulin level after 5 years was 10 mU/l. Median postprandial insulin values also rose, yet remained within the normal range at the 5-year mark. Mean Hb A1c levels remained within low to middle end of the normal range in the patients with growth hormone deficiency, Turner syndrome, and idiopathic short stature. Mean Hb A1c levels at the 5 years were slightly elevated to 6.3% for the patients with chronic renal insufficiency. 相似文献
82.
83.
84.
85.
Data concerning rural youth drinking and driving practices werecollected from 622 junior and senior high school students innorthwest Ohio, utilizing an ex post facto cross-sectional survey-researchdesign. The results suggested that 69% of the sample had usedalcohol at least once. With regard to quantity of alcohol use,about 27% reported drinking four or more drinks at a sitting.Approximately 19% of the sample had driven under the influenceof alcohol and 35% had ridden in a car with an intoxicated school-agedriver; 35% had refused a ride from a friend who was intoxicated,while 43% had tried to stop a drunk friend from driving. Nosignificant differences were found between males and femalesregarding drinking and driving but grade level was a significantmoderating factor. As grade level increased, the frequency ofeach alcohol-related behavior increased substantially (P <0.01). This paper presents prevalence data concerning drinkingand driving among rural youth as well as recommendations forcommunity health education program development. 相似文献
86.
87.
Paul Moorehead 《Canadian Medical Association journal》2005,172(11):1475
88.
89.
Rene C. Bakker Eduard M. Scholten Johan W. de Fijter Leendert C. Paul 《Transplantation reviews (Orlando, Fla.)》2004,18(1):54-64
Although extensively studied, the pathophysiologic characteristics of chronic cyclosporine (CsA) nephrotoxicity are still far from being completely understood. The recognition of chronic CsA nephrotoxicity in allografted kidneys is hampered by a lack of easily assessable sensitive and specific markers. Long-term results of CsA withdrawal trials and trials that evaluated CsA sparing or withdrawal after the diagnosis of chronic allograft nephropathy (CAN) have shown that chronic CsA nephrotoxicity has a more important role in the etiology of late transplant dysfunction than appreciated before. Various hypotheses have explained the renal structural changes of chronic CsA nephrotoxicity including ischemia, cellular toxicity, and the stimulation of renal fibrosis by growth factors or cytokines. Possible ways to prevent chronic CsA nephrotoxicity include improved therapeutic drug monitoring and CsA withdrawal or avoidance. Patients with aspecific CAN in late biopsy may benefit from withdrawal of CsA or a reduction of its dose. Current knowledge is being discussed. It is concluded that in the near future more strategies are likely to be used to prevent loss of allograft function as a result of drug toxicity. 相似文献
90.
Heather S. Jim Michael A. Andrykowski Pamela N. Munster Paul B. Jacobsen 《Annals of behavioral medicine》2007,34(2):200-208
Background: Studies suggest that the period following completion of treatment can be distressing for cancer patients. One potentially
important predictor of distress is physical symptoms/side effects during treatment.Purpose: A longitudinal, observational design was used to examine whether the number of physical symptoms/side effects experienced
during treatment was a correlate of cancer-related distress and general distress 4 months after treatment completion, as measured
by the Impact of Events Scale and the Mental Health subscale of the Short Form-36, respectively.Methods: Participants were 151 women who had completed chemotherapy and/or radiotherapy for ductal carcinoma in situ or stage 1 or
2 breast cancer. Hierarchical multiple regression was conducted with relevant sociodemographic, clinical, and psychiatric
variables entered as controls.Results: Greater physical symptoms/side effects predicted greater total cancer-related distress, intrusive thoughts, and general distress.
Physical symptoms/side effects did not significantly predict avoidance. Follow-up analyses indicated that the relationship
between physical symptoms/side effects and general distress was mediated by both total cancer-related distress and intrusive
thoughts.Conclusions: These results suggest that patients who experience greater physical symptoms/side effects during treatment are at greater
risk for later cancer-related distress and, in turn, general distress. Future research should evaluate whether early intervention
with these patients is effective in preventing or reducing distress in the posttreatment period.
This work was supported by a grant from the National Cancer Institute (5R01 CA082822). 相似文献