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排序方式: 共有1084条查询结果,搜索用时 15 毫秒
31.
Richard A. Deyo Samuel F. Dworkin Dagmar Amtmann Gunnar Andersson David Borenstein Eugene Carragee John Carrino Roger Chou Karon Cook Anthony DeLitto Christine Goertz Partap Khalsa John Loeser Sean Mackey James Panagis James Rainville Tor Tosteson Dennis Turk Michael Von Korff Debra K. Weiner 《European spine journal》2014,23(10):2028-2045
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34.
Haris Georgiou Vasileios Patris Niki Lama Orestis Argiriou Kostas Soultanis 《International journal of surgery case reports》2014,5(10):703-705
INTRODUCTION
Right ventricular (RV) rupture with mediastinitis, is a very rare but extremely dangerous (even fatal) complication, following CABG surgery.PRESENTATION OF CASE
In this paper, we present the case of a post-trauma (after fall) RV rupture (without mediastinitis) in a patient who had undergone cardiac surgery several days ago. The cause of the rupture proved to be a broken bone piece from the lower sternal edge.DISCUSSION
RV rupture post-operatively caused by broken bone pieces or bone dislocation may occur through two mechanisms: either penetration of the RV, or through the “sandpaper effect”. In order to prevent the rupture, we should be able to recognize patients with aggravating factors (age, weight) and choose intra-operatively a suitable closure technique.CONCLUSION
We propose that the technique that could prevent such ruptures is the Robicsek technique. 相似文献35.
Objective
A number of studies provide supporting evidence for changes in synchronization during anesthetic-induced unconsciousness. This study investigates how anesthetic administration affects the widespread patterns of phase synchrony.Methods
The recently introduced method of Spatial Analytic Phase Difference (SAPD) was used to measure changes in synchrony in the electroencephalogram (EEG) activity of 29 patients undergoing routine surgery. Analysis was performed over 9 frequency bands: (i) δ (1.5–3.5 Hz); (ii) θ (3.5–7.5 Hz); (iii) α1 (8–10 Hz); (iv) α2 (10.5–12 Hz); (v) β1 (12.5–18 Hz); (vi) β2 (18.5–21 Hz); (vii) β3 (21.5–30 Hz); (viii) γ1 (30.5–40 Hz); and (ix) γ2 (60–80 Hz).Results
Anesthesia was characterized by (a) large and localized synchrony increases in mid-frequency bands (8–12 Hz), (b) smaller and widespread synchrony increases in higher frequency bands (30.5–40 Hz, 60–80 Hz), and (c) both increase and decrease of synchrony in low frequency bands (1.5–7.5 Hz).Conclusions
This study supports anesthetic-induced changes in synchrony, with the inducement of persistent and reversible widespread γ synchrony being most prominent.Significance
Our findings have implications in the study of consciousness, support existing literature in the field and contribute towards the theoretical understanding of the mechanisms behind loss of consciousness. Future investigations could result in a synchrony-based measure for monitoring the level of hypnosis of patients during surgery. 相似文献36.
Maria Syrrou Philippos C. Patsalis Ioannis Georgiou Michael I. Hadjimarcou C. D. Constantinou-Deltas Gerassimos Pagoulatos 《American journal of medical genetics. Part A》1996,64(1):234-238
The expansion of the trinucleotide repeat (CGG)n in successive generations through maternal meiosis is the cause of fragile X syndrome. Analysis of CA repeat polymorphisms flanking the FMR-1 gene provides evidence of a limited number of “founder” chromosomes and predisposing high-risk haplotypes related to the mutation. To investigate the origin of mutations in the fragile X syndrome in the Hellenic populations of Greece and Cyprus, we studied the alleles and haplotypes at DXS548 and FRAXAC2 loci of 16 independent fragile X and 70 normal control chromosomes. In addition, we studied 191 unrelated normal X chromosomes for the distribution and frequencies of CGG alleles. At DXS548, 6 alleles were found, 2 (194 and 196) of which were represented on fragile X chromosomes. At FRAXAC2, 6 alleles were found, 4 of which were present on fragile X chromosomes. Sixteen haplotypes were identified, but only 5 were present on fragile X chromosomes. The highest number of CGG repeats (≥ 33) were associated with haplotypes 194-147, 194-151, 194-153, and 204-155. The data provide evidence for founder chromosomes and high-risk haplotypes in the Hellenic population. © 1996 Wiley-Liss, Inc. 相似文献
37.
Maria Chatzopoulou Katrina S. Madden Liam J. Bromhead Christopher Greaves Thomas J. Cogswell Solange Da Silva Pinto SbastienR. G. Galan Irene Georgiou Matthew S. Kennedy Alice Kennett Geraint Apps Angela J. Russell Graham M. Wynne 《ACS medicinal chemistry letters》2022,13(2):262
Palladium-catalyzed reactions are among the most commonly used procedures in organic synthesis. The products have a range of uses, including as intermediates in total synthesis and as screening compounds for drug discovery or agrochemical projects. Despite the known and potentially deleterious effects of low-level metal impurities in biological assays, the quantification of metal remaining in reaction products to verify the effective removal of the transition element is rarely reported. Using palladium as an exemplar, we describe a pilot study that for the first time quantifies residual metal levels in reaction products following increasingly rigorous purification protocols. Our results demonstrate that significant levels of residual palladium can remain in isolated reaction products following chromatographic purification, and only by using a subsequent metal scavenging step are they reliably reduced to a low level. Finally, we provide a set of simple guidelines that should minimize the potential for issues associated with residual palladium in reaction products. 相似文献
38.
Sakellari Evanthia Vasiliou Eleni Konstantinou Christall Chrisanthou Antri Georgiou Anna Papadini Milena Vlachou Vasso Sapountzi-Krepia Despina 《International journal of mental health and addiction》2020,18(5):1458-1465
International Journal of Mental Health and Addiction - The purpose of this study was to explore the relationship between anxiety, self-esteem, and depression among students of economic sciences and... 相似文献
39.
Despina I Papadopoulou Emmanouel N Yakoumakis Triantafillia K Makri Panagiotis H Sandilos Basil D Thanopoulos Evangelos K Georgiou 《Catheterization and cardiovascular interventions》2005,65(3):434-441
The purpose of this study was to estimate the radiation dose to which children are exposed during cardiac catheterizations for the treatment of ventricular and atrial septal defects. Radiation doses were estimated for 46 children aged 1-18 years. These children were treated for secundum atrial septal defects (ASD group) for perimembranous ventricular septal defects (VSD group) or underwent a routine diagnostic catheterization (diagnostic group). Thermoluminescent dosimeters (TLDs) were attached in locations, representing the lateral entrance dose, the posterior entrance dose, the thyroid dose, and the gonad dose, respectively. A dose area product (DAP) meter was also attached externally on the posterior-anterior (PA) tube to give a direct value in cGy cm(2) for each procedure. The patient's entrance dose from the PA field ranged from 1.5 to 185.0 mGy for all patients, while the lateral entrance dose varied from 0.9 to 204 mGy. Radiation exposure to the thyroid and the gonads was found to vary from 0.4 to 8.3 and 0.1 to 2.1 mGy, respectively. The DAP meter recorded DAP values for the posterior tube, between 46 and 3,700 cGy cm(2). The mean effective dose was found to be 7.7, 16.2, and 33.3 mSv for the diagnostic, the ASD, and the VSD group, respectively. Very strong correlation was found between the DAP values and the entrance radiation dose measured with TLDs. The mean entrance dose received from therapeutic cardiac catheterizations using the Amplatzer devices was found approximately twice the dose received from a diagnostic one. Even for the most complex procedures, the maximum entrance dose was at least 10 times lower than the threshold, associated with skin erythema. 相似文献
40.
Nicolaides AN Kakkos SK Griffin M Sabetai M Dhanjil S Thomas DJ Geroulakos G Georgiou N Francis S Ioannidou E Doré CJ;Asymptomatic Carotid Stenosis Risk of Stroke 《Vascular》2005,13(4):211-221
The aim of this study was to determine the effect of image normalization on plaque classification and the risk of ipsilateral ischemic neurologic events in patients with asymptomatic carotid stenosis. The first 1,115 patients recruited to the Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) study with a follow-up of 6 to 84 months (mean 37.1 months) were included in this study. Duplex ultrasonography was used for grading the degree of internal carotid artery stenosis and for plaque characterization (types 1-5), which was performed before and after image normalization. One hundred sixteen ipsilateral ischemic hemispheric events occurred. Image normalization resulted in 60% of plaques being reclassified. Before image normalization, a high event rate was associated with all types of plaque. After image normalization, 109 (94%) of the events occurred in patients with plaque types 1 to 3. For patients with European Carotid Stenosis Trial (ECST) 70 to 99% diameter stenosis (equivalent to North American Symptomatic Carotid Endarterectomy Trial [NASCET] 50-99%) with plaque types 1 to 3, the cumulative stroke rate was 14% at 7 years (2% per year), and for patients with plaque types 4 and 5, the cumulative stroke rate was 0.9% at 7 years (0.14% per year). The results suggest that asymptomatic patients with plaque types 4 and 5 classified as such after image normalization are at low risk irrespective of the degree of stenosis. 相似文献