Screening the newborn for developmental dysplasia of the hip: now what do we do?

The Pediatric Orthopaedic Society of North America recommends that all health care providers who are involved in the care of infants continue to follow the clinical practice guideline for early detection of developmental hip dysplasia (DDH) outlined by the American Academy of Pediatrics. Although evaluation of children with risk factors for DDH is important, most DDH occurs in infants who have no risk factors. For all infants, a competent newborn physical examination using the Ortolani maneuver is the most useful procedure to detect hip instability. Early treatment of an unstable hip with a Pavlik harness or similarly effective orthosis is effective, safe, and strongly advised. Despite having had normal newborn and infant hip examinations, there remains the possibility of a late-onset hip dislocation needing treatment in approximately 1 in 5000 infants.     

Guideline for the management of the hot swollen joint in adults with a particular focus on septic arthritis

The British Society for Rheumatology (BSR) Standards, Guidelines and Audit Working Group, in conjunction with the British Society for Antimicrobial Chemotherapy, British Orthopaedic Association, Royal College of General Practitioners and British Health Professionals in Rheumatology, has produced an evidence-based guideline for the management of the hot swollen joint with particular focus on the septic joint. The aim of the guideline is to help accurate diagnosis and appropriate treatment when a joint is hot because of sepsis, while also ensuring that other causes such as crystal arthritis are recognized and not over-treated.     

医院行政管理人员及行政管理工作中的问题与对策

分析了现阶段医院行政管理人员现状及存在的问题：管理经验少、行政人员个人因素、部门职责交叉重叠、部门之间协调机制运转不畅、行政管理流程不合理以及人力资源管理滞后。在此基础上,提出了提高医院行政管理人员的综合素质、完善医院内部协调机制,增进部门之间的沟通协作、有效消除管理职责的“真空”地带、优化医院行政管理流程、加快推进医院人事制度改革,培养医院管理职业人团队等具体对策。     

科技编辑突出重点方法初探

对科技编辑突出重点方法的内容、方法论意义、理论依据及其在编辑活动的实际应用进行初步探讨。科技编辑突出重点方法渗透于从选题、组稿、审读、加工、出版、发行到经营管理的各个环节,将其合理应用,对于提高编辑工作效率是十分有益的。     

聚乳酸和无活性脱钙骨基质载体对rhBMP-2异位诱导骨形成的比较性研究

目的：为了研究聚乳酸和无活性脱钙骨基质载体对ｒｈＢＭＰ－２异位诱导的骨形成。方法：将重组人骨形态发生蛋白－２（ｒｈＢＭＰ－２）与无活性脱钙骨基质（ＤＢＭ）和聚乳酸（ＰＬＡ）复合,植入小鼠股部外侧肌肉陷窝比较ＰＬＡ和ＤＢＭ载体对ｒｈＢＭＰ－２诱导骨形成的影响。通过组织学检查、碱性磷酸酶（ＡＬＰ）和钙含量测定以及骨钙素（ＢＧＰ）放疫测定,进行对比观察。结果：术后２１天,实验组均可见新生软骨细胞和软骨岛,ｒｈＢＭＰ－２／ＰＬＡ和ＤＢＭ／ｒｈＢＭＰ－２组还可见部分骨组织形成,见骨小梁、板层结构和红骨髓,ｒｈＢＭＰ－２／ＰＬＡ组ＰＬＡ部分吸收,ＤＢＭ／ｒｈＢＭＰ－２组ＤＢＭ无吸收迹象。各实验组与对照组对比,ＡＬＰ、ＢＧＰ水平和Ｃａ量均有显著性差异（Ｐ＜０．０５）,ｒｈＢＭＰ－２／ＰＬＡ与ＤＢＭ／ｒｈＢＭＰ－２组在ＡＬＰ和ＢＧＰ水平上相比无显著差异（Ｐ＞０．０５）,但前组比后组的Ｃａ量为高（Ｐ＜０．０５）,这二组与单独植入ｒｈＢＭＰ－２组相比,定量检测指标均有显著性差异（Ｐ＜０．０５）。结论：（１）ＰＬＡ和ＤＢＭ均为ＢＭＰ的良好载体;（２）ｒｈＢＭＰ－２／ＰＬＡ是一种新的有价值的骨修复材料     

趋化性模型的建立及神经生长因子的趋化作用

目的 在体外建立神经组织生长趋化性模型,探讨神经生长因子（ＮＧＦ）对神经组织的趋化作用。方法 直径约１ｍｍ的玻璃毛细管吸取约１０μｌ的染料溶液,观察染料在培养液中的扩散,同样毛细管吸取含ＮＧＦ的溶液与鸡胚神经节共培养,观察神经组织的生长上径１ｍｍ的毛细管可稳定吸取１μｌ的液体,吸取的染料在细管周转分布均匀的浓度梯度;培养的神经节组织向高ＮＧＦ浓度深度度方向生长。结论 毛细管模型是研究神经组织趋化性     

中药敷贴对住院骨折患者术后腹胀的疗效观察

目的:观察中药敷料贴脐消除骨折术后腹胀的疗效。方法:对160例骨折术后患者腹胀随机分成排气汤组、敷贴组和对照组,观察消除腹胀的疗效。结果:排气汤组和敷贴组对骨折术后腹胀有明显的疗效(P0.05)。结论:中药敷料贴脐因显效、方便,可以作为治疗骨折术后腹胀的有效方法。