首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1334376篇
  免费   95986篇
  国内免费   2907篇
耳鼻咽喉   19737篇
儿科学   40240篇
妇产科学   38667篇
基础医学   187277篇
口腔科学   39829篇
临床医学   112585篇
内科学   262315篇
皮肤病学   30232篇
神经病学   106399篇
特种医学   53688篇
外国民族医学   435篇
外科学   208366篇
综合类   31031篇
现状与发展   6篇
一般理论   436篇
预防医学   91936篇
眼科学   31346篇
药学   100090篇
  3篇
中国医学   2988篇
肿瘤学   75663篇
  2018年   11754篇
  2015年   11883篇
  2014年   16705篇
  2013年   25257篇
  2012年   33038篇
  2011年   34905篇
  2010年   20745篇
  2009年   20244篇
  2008年   33617篇
  2007年   36731篇
  2006年   37290篇
  2005年   36058篇
  2004年   35144篇
  2003年   34106篇
  2002年   33632篇
  2001年   63629篇
  2000年   65336篇
  1999年   55403篇
  1998年   14667篇
  1997年   13465篇
  1996年   12945篇
  1995年   12227篇
  1994年   11474篇
  1992年   42775篇
  1991年   41299篇
  1990年   40576篇
  1989年   39573篇
  1988年   36983篇
  1987年   36429篇
  1986年   34917篇
  1985年   33120篇
  1984年   24834篇
  1983年   21064篇
  1982年   12674篇
  1981年   11572篇
  1980年   10777篇
  1979年   23932篇
  1978年   17079篇
  1977年   14838篇
  1976年   13387篇
  1975年   15273篇
  1974年   18083篇
  1973年   17562篇
  1972年   16813篇
  1971年   15722篇
  1970年   14917篇
  1969年   14351篇
  1968年   13467篇
  1967年   12025篇
  1966年   11263篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
151.
152.
153.
154.
155.
156.

Background

Inflammation and infections have been associated with prostate cancer progression. We assessed whether elevated serum cytokines or T. vaginalis seropositivity at the time of diagnosis was associated with higher grade or lethal prostate cancer.

Patients and Methods

Men with localized or metastatic prostate cancer were included in this study. Cytokine serum levels including interleukin (IL)-1α, IL-1β, IL-2, IL-6, IL-8, monocyte chemotactic protein 1 (CCL-2), tumor necrosis factor α, and growth-regulated oncogene α (CXCL-1) using a multiplex enzyme-linked immunosorbent assay and T. vaginalis serology were measured in blood samples at diagnosis.

Results

A total of 324 patients were identified at time of localized disease and 118 at time of metastatic disease. Of the 189 patients with localized disease and clinical follow-up data (median, 73 months), 28 developed lethal disease. There was no association between circulating cytokine levels above median concentrations nor T. vaginalis seropositivity and risk of intermediate- to high-risk or lethal prostate cancer.

Conclusion

Higher levels of serum cytokine levels and T. vaginalis seropositivity at diagnosis are not associated with high-grade or lethal prostate cancer and do not aid risk stratification of localized prostate cancer.  相似文献   
157.

Objective

The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.

Patients and methods

We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.

Results

A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.

Conclusions

This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses.  相似文献   
158.
Struan H. Coleman 《Arthroscopy》2019,35(4):1109-1110
Dancers have a disproportionately high prevalence of hip issues compared with other types of athletes. Many of these hip issues are complex: a cam and/or pincer impingement combined with a seemingly paradoxical borderline dysplasia, capsular laxity, and subsequent instability. Our experience as nonarthritic hip surgeons tells us that careful patient selection is critical for a successful outcome after the arthroscopic treatment of a dancer. But, there is little guidance in the literature on the management of this specific group of patients. We have studies that advise us to repair the labrum when possible versus performing labral debridement in female patients with predominantly pincer-type impingement and studies that support capsular plication and careful capsule closure in patients, predominantly female patients, with combined hip impingement and dysplasia or borderline dysplasia. However, few studies have examined predictors of outcomes after hip arthroscopy in dancers.  相似文献   
159.
160.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号