全文获取类型
收费全文 | 106篇 |
免费 | 1篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 5篇 |
妇产科学 | 7篇 |
基础医学 | 6篇 |
口腔科学 | 12篇 |
临床医学 | 9篇 |
内科学 | 49篇 |
皮肤病学 | 1篇 |
神经病学 | 1篇 |
外科学 | 10篇 |
预防医学 | 4篇 |
肿瘤学 | 2篇 |
出版年
2022年 | 2篇 |
2021年 | 5篇 |
2019年 | 2篇 |
2018年 | 6篇 |
2016年 | 2篇 |
2015年 | 1篇 |
2014年 | 7篇 |
2013年 | 14篇 |
2012年 | 9篇 |
2011年 | 10篇 |
2010年 | 5篇 |
2009年 | 3篇 |
2007年 | 5篇 |
2006年 | 5篇 |
2004年 | 2篇 |
2003年 | 4篇 |
2002年 | 7篇 |
2001年 | 6篇 |
2000年 | 2篇 |
1999年 | 2篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1996年 | 2篇 |
1991年 | 1篇 |
排序方式: 共有107条查询结果,搜索用时 15 毫秒
91.
92.
93.
94.
Abdoul Kane Mariana Mirabel Kamadore Touré Marie-Cécile Périer Samia Fazaa Muriel Tafflet Nicole Karam Ibrahim Zourak Dior Diagne Alassane Mbaye Moussa Kane Bouna Diack Xavier Jouven Eloi Marijon 《International journal of cardiology》2013
Background
Echocardiography is emerging as a screening tool for rheumatic heart disease (RHD) in endemic regions. The vast majority of surveys have been limited to children. We ought to appreciate the interest of including adolescents in their late teens in such school screening programmes.Methods
School-based echocardiography cross-sectional survey conducted in Dakar, Senegal (March 2010). A total of 2004 school attendees were randomly selected and enrolled in the study, among which 1116 were aged 5–15 years old (group 1), and 888 were 16–18 years old (group 2). Case detection rates and phenotype of RHD were compared according to age groups.Results
A total of 22 youngsters were suspected by on-site echocardiography, 12 in group 1 and 10 in group 2. Among the 12 RHD cases suspected on-site in group 1, 6 (50%) were eventually considered as confirmed RHD, compared to 9 out of 10 (90%) in group 2, giving prevalence rates of 5.4 (CI 95% 2.0–11.7) and 10.1 (CI 95% 4.6–19.2) per 1000 in group 1 and group 2, respectively. The proportion of marked/advanced lesions was 33% in group 1, and 89% in group 2 (p = 0.08). Mean concordance rates between the 3 reviewers were 40% for group 1, compared to 93% in group 2 (p = 0.05).Conclusions
Extension of screening to adolescents in their late teens should be considered with interest in the light of the higher prevalence of the disease and relative clarity of subclinical cardiac lesions that could be more easily detected in the field. 相似文献95.
96.
P. A. Bâ M. M. Diop S. A. Soumah B. Diop E. M. Mbaye B. Fall 《Journal Africain d'Hépato-Gastroentérologie》2013,7(1):50-52
Rectal foreign bodies are uncommon in our practice. In adult, foreign bodies are mostly inserted into the rectum for sexual gratification. We report the case of 49 years old man, who present to the emergency department with constipation following accidental insertion of a deodorant bottle in the rectum. Nonoperative treatment based on laxatives allow the expulsion of the foreign body. Through this case, we discuss diagnosis and therapeutic aspects of rectal foreign bodies. 相似文献
97.
BACKGROUND: In rural Africa, women and adolescent girls sustain a high burden of domestic and agricultural tasks. This could result in energy imbalance and impair their nutritional status. OBJECTIVE: The aim of the study was to investigate activity during the day and time spent in bed during the night for adult women and adolescent and preadolescent girls living in the same household. The hypothesis was that more prolonged physical inactivity and time spent in bed could be an efficient means for lowering energy expenditure and hence maintaining an adequate nutritional state. METHODS: Physical activity during the day was qualitatively recorded using 'spot observation' (Super 1989), and quantitatively using accelerometers. A total of 110 females--55 adult women, 45 adolescents and 10 preadolescents--were included in the study. Anthropometric measurements (weight, height and four subcutaneous skinfolds) served as indicators of nutritional status. RESULTS: Day-to-day reliability of accelerometry counts was acceptable (average intraclass correlation coefficient = 0.73). Differences in daytime activity varied according to age group. Adolescent and preadolescent girls had higher overall activities than adults (p < 0.01). Preadolescent girls went to bed earlier and for longer periods than adult women (p < 0.001). There existed significant relationships between time spent in bed and activity during the day in adult women but not in adolescent or preadolescent girls. A significant relationship between nutritional status and physical activity indices was observed in preadolescent and adolescent girls, but not in women. CONCLUSIONS: The findings partially support the hypothesis of some compensation of daytime activity by time spent in bed in adult women, but not in adolescent or preadolescent girls. 相似文献
98.
Nathalie Wurtz Bécaye Fall Aurélie Pascual Mansour Fall Eric Baret Cheikhou Camara Aminata Nakoulima Bakary Diatta Khadidiatou Ba Fall Pape Saliou Mbaye Yaya Diémé Raymond Bercion Boubacar Wade Bruno Pradines 《Antimicrobial agents and chemotherapy》2014,58(12):7032-7040
The involvement of Pfmdr1 (Plasmodium falciparum multidrug resistance 1) polymorphisms in antimalarial drug resistance is still debated. Here, we evaluate the association between polymorphisms in Pfmdr1 (N86Y, Y184F, S1034C, N1042D, and D1246Y) and Pfcrt (K76T) and in vitro responses to chloroquine (CQ), mefloquine (MQ), lumefantrine (LMF), quinine (QN), monodesethylamodiaquine (MDAQ), and dihydroartemisinin (DHA) in 174 Plasmodium falciparum isolates from Dakar, Senegal. The Pfmdr1 86Y mutation was identified in 14.9% of the samples, and the 184F mutation was identified in 71.8% of the isolates. No 1034C, 1042N, or 1246Y mutations were detected. The Pfmdr1 86Y mutation was significantly associated with increased susceptibility to MDAQ (P = 0.0023), LMF (P = 0.0001), DHA (P = 0.0387), and MQ (P = 0.00002). The N86Y mutation was not associated with CQ (P = 0.214) or QN (P = 0.287) responses. The Pfmdr1 184F mutation was not associated with various susceptibility responses to the 6 antimalarial drugs (P = 0.168 for CQ, 0.778 for MDAQ, 0.324 for LMF, 0.961 for DHA, 0.084 for QN, and 0.298 for MQ). The Pfmdr1 86Y-Y184 haplotype was significantly associated with increased susceptibility to MDAQ (P = 0.0136), LMF (P = 0.0019), and MQ (P = 0.0001). The additional Pfmdr1 86Y mutation increased significantly the in vitro susceptibility to MDAQ (P < 0.0001), LMF (P < 0.0001), MQ (P < 0.0001), and QN (P = 0.0026) in wild-type Pfcrt K76 parasites. The additional Pfmdr1 86Y mutation significantly increased the in vitro susceptibility to CQ (P = 0.0179) in Pfcrt 76T CQ-resistant parasites. 相似文献
99.
100.
This study was conducted in the three main hospitals of Dakar, the capital city of Senegal. Each case of 152 maternal deaths identified over a 12-month period was matched with two controls: a safe delivery in the same clinic, and a safe delivery in the same neighbourhood of residence. Controls were matched on age, birth order, place, and time of delivery. The leading causes of death were: puerperal sepsis and other infections (51 cases), haemorrhage (32 cases), eclampsia (29 cases), ruptured uterus (11 cases), and anaemia (7 cases). Results of the case-control study revealed the major risk factors associated with health system failures: medical equipment failure (odds ratio [OR] = 55.0), late referral (OR = 23.2), lack of antenatal visit (OR = 16.9), and lack of available personnel at time of admission (OR = 6.6). Various indicators of maternal status at time of admission (complications, blood pressure, temperature, oedema, haemoglobin level) and of health history prior to admission (previous complications, previous C-section, lack of treatment) were also strong predictors of survival. Lastly, socio-demographic factors also appeared as correlates of maternal mortality, in particular: first pregnancy (OR = 2.3), pregnancy of high birth order (OR = 1.9), rainy season (OR = 2.4), being unmarried (OR = 2.5), and low level of education (OR = 1.6). Implications for policy are discussed. 相似文献