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991.
Mahran Shoukier MD Tapan Kadia MD Marina Konopleva MD PhD Ahmad S. Alotaibi MD Mansour Alfayez MD Sanam Loghavi MD Keyur P. Patel MD PhD Rashmi Kanagal-Shamanna MD Jorge Cortes MD Bachar Samra MD Elias Jabbour MD Guillermo Garcia-Manero MD Koichi Takahashi MD PhD Sherry Pierce RN BS BA Nicholas J. Short MD Musa Yilmaz MD Koji Sasaki MD PhD Lucia Masarova MD Naveen Pemmaraju MD Gautam Borthakur MD Hagop M. Kantarjian MD Farhad Ravandi MD Courtney D. DiNardo MD Naval Daver MD 《Cancer》2021,127(3):381-390
992.
Abhishek Maiti MBBS Courtney D. DiNardo MD MSCE Wei Qiao PhD Tapan M. Kadia MD Elias J. Jabbour MD Caitlin R. Rausch PharmD Naval G. Daver MD Nicholas J. Short MD Gautam Borthakur MD Naveen Pemmaraju MD Musa Yilmaz MD Yesid Alvarado MD Kathryn S. Montalbano RN Allison Wade RN Rita E. Maduike RN Julio A. Guerrero RN Kenneth Vaughan RN Carol A. Bivins RN Sherry Pierce RN Jing Ning PhD Farhad Ravandi MD Hagop M. Kantarjian MD Marina Y. Konopleva MD PhD 《Cancer》2021,127(22):4213-4220
993.
Mehre Shrikant A. Dhara Ashis Kumar Garg Mandeep Kalra Naveen Khandelwal Niranjan Mukhopadhyay Sudipta 《Journal of digital imaging》2019,32(3):362-385
Journal of Digital Imaging - Lung cancer manifests itself in the form of lung nodules, the diagnosis of which is essential to plan the treatment. Automated retrieval of nodule cases will assist the... 相似文献
994.
Kumar R Srivastava P Kumari D Fakhr H Sridhara S Arora N Gaur SN Singh BP 《Immunobiology》2007,212(2):141-147
Sensitization to foods varies in different countries reflecting a possible interaction of genetic factors, cultural and dietary habits. Rice is a major food consumed world wide and needs evaluation for IgE mediated reactions. The present study was carried out to identify rice allergy in patients of rhinitis and asthma and identify the allergenic proteins in raw and cooked rice. Of 1200 patients screened using standard questionnaire, 165 presented with history of rice allergy. Of these, 20 (12.1%) patients demonstrated marked positive skin prick test (SPT) and 13 showed significantly raised specific IgE to rice compared to normal controls. Double blind placebo controlled food challenge (DBPCFC) confirmed rice allergy in 6/10 patients. Immunoblot with hypersensitive individual patients' sera showed 14-16, 33, 56 and 60 kDa proteins as major IgE-binding components in rice. Boiled rice retained four IgE reactive proteins of 16, 23, 33 and 53 kDa. In summary, IgE-mediated rice allergy affects 0.8% [(0.42-1.58) at 95% CI] of asthma and rhinitis cases. The subjects with severe SPT reactions (4 mm or above) and specific IgE, 6.9 ng/ml to rice demonstrated positive blinded food challenge with clinical symptoms. 相似文献
995.
996.
Shukla PK Upadhyay S Kumar B Thapliyal N Saxena SR Joshi D 《Indian journal of pathology & microbiology》2007,50(1):70-74
Haemoglobin-S has been reported in several studies on remote populations from various parts of India eg Maharashtra, Madhya Pradesh, Andhra Pradesh, Orissa, West Bengal, Rajasthan and Malaysian Indians. Uttaranchal also has got scattered areas with people living in remote-pockets due to its geophysical nature. There has been no previous report from this state about prevalence of Hb-S. In the present study on 38 individual eight were found to have Hb-S positivity by sickling test. In one of these electrophoretic confirmation was positive with demonstration of associated Beta thalassaemia. The group was a family of muslims in village Baghori near Haldwani. Due to technical, geographical and social restrictions further study could not be done. However, this study does establish the presence of Hb-S-Beta thalassaemia in Uttaranchal State for the first time. Follow up study in the affected area and elsewhere in the state might discover more of Hb-S positivity, other haemoglobinopathies and thalassaemias. 相似文献
997.
Allergenic proteins in extracts degrade rapidly and lose potency on storage. Hence, formulation of optimum conditions is required
to enhance shelf life of extracts for proper allergy diagnosis and immunotherapy. In the present study, allergenic potency
of P. americana proteins was evaluated after storage with ε-aminocaproic acid (EACA), sucrose, glycerol, pepstatin A, and aprotinin, individually
for 1, 3, 6, and 12 months at 4, 25, and 37°C. P. americana extract stored with EACA and sucrose individually retained potency comparable to proteins in standard extract (freeze-dried
extract, stored at−70°C) upto 6 months at 4°C. The extracts without preservatives or with glycerol, pepstatin A, aprotinin,
or stored at 37/25°C were severely degraded and lost potency by 3 months. A formulation containing a combination of EACA and
sucrose enhanced the shelf life of P. americana proteins upto 12 months at 4°C. Hence, EACA and sucrose together show better potential for stabilization of protease-rich
extracts. 相似文献
998.
Miguel-Angel Perales Emily K. Drake Naveen Pemmaraju William A. Wood 《Current hematologic malignancy reports》2016,11(6):449-455
Over 70,000 adolescent and young adults (AYA) aged 15 to 39 years are diagnosed with cancer each year in the US. The National Cancer Institute (NCI) has identified AYA cancer patients as a unique population. The most common cancers in this age group include tumors typically seen in pediatric patients such as acute lymphoblastic leukemia (ALL) and brain tumors, as well as cancers more typically seen in adult patients such as breast cancer and melanoma. In addition, some cancers have their highest incidence in AYA patients, such as Hodgkin Lymphoma, testicular cancer, and bone tumors. AYA patients face additional unique issues due to their age, not just questions about treatment choices due to lack of data but also questions about fertility, relationships, loss of autonomy, and interruptions in school/work with potentially significant financial complications. This age group also has very high rates of social media usage with up to 90 % of adults aged 18 to 29 using social networking sites. In this review, we will describe the use of social media in AYAs with cancer and highlight some of the online resources for AYAs. 相似文献
999.
Gebreegziabher Y McCullough PA Bubb C Loney-Hutchinson L Makaryus JN Anand N Divakaran V Akhrass P Alam A Gizycki Hv McFarlane SI 《Congestive heart failure (Greenwich, Conn.)》2008,14(3):117-120
The authors assessed the relationship between glycemia and length of hospital stay (LOS) in a prospective cohort study of patients with diabetes mellitus and heart failure (HF). Of 212 patients with acute HF exacerbation, 119 (56%) also had diabetes. The mean age of the cohort was 63+/-0.87 years, and the mean body mass index was 29.3 kg/m2. Diabetic patients had significantly longer LOS compared with the nondiabetics (5.0+/-0.29 vs 3.4+/-0.19; P<.001). In patients with diabetes, the mean glycated hemoglobin A1c was 8.3%, admission blood glucose (BG) was 169+/-7.7 mg/dL, and average BG was 196+/-8.1 mg/dL. After adjusting for age, sex, weight, hypertension, renal function, and anemia, LOS was significantly correlated with admission BG (r=0.31; P<.001) and average BG (r=0.34; P=.001). In patients with acute HF exacerbation, diabetes significantly prolonged LOS. Hyperglycemia correlated with LOS. 相似文献
1000.